David Feder Email & Phone Number

• As member of the biophysics group within the Biotherapeutics Discovery Department, perform in-depth biophysical analysis of various proteins, including AUC, UPLC/HPLC and DLS.
• Fluorescently labeled various proteins and performed AU-FDS experiments in buffer and in serum testing antigen/antibody complex formation and size.
• Possess a fundamental understanding of protein structure function relationship.
• Drove high priority enzyme kinetic study involving the development of enzymatic assays to test kinetics of a target enzyme and the antibodies that act as inhibitors.
• Used GE AKTA system to purify various antibodies using methods in chromatography.
• Enzymatically generated Fab fragments and purified them via chromatography, which were used in various aspects of biotherapeutics research, including crystallography and binding studies.

Brooklyn, NY

• Expressed recombinant proteins on fermenter scale
• Gained Experience in various methods of protein purification
• Proficient in methods of protein analysis and quantification, such as SDS-PAGE and colorimetric assays
• Proficient in multiple techniques of protein immobilization.
• Experienced in polymer synthesis and performing extensive characterization of polymer products using various methods of chromatography and spectroscopy
• Conducted in-depth studies comparing activity, selectivity and thermostability of novel and commercially available enzyme catalysts for chemical transformations

• Guided Graduate students in laboratory techniques and research methodologies

Phd, Biomedical Engineering (Materials)

Dissertation: Humicola insolens cutinase; a novel catalyst for polymer synthesis reactions Thesis adviser: Professor Richard A. Gross.

Ms, Systems Engineering