David Gagne Email and Phone Number
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My technical ability is one of my greatest assets, as I can grasp new procedures quickly and perform them with accuracy. I pride myself in creating reliable and repeatable data with a sense of urgency. I am known to be an excellent team member who is always there for support and working to improve communication. I have the desire to work in the vivarium, at the bench, or wherever I can make the most positive impact for the company.• Extensive experience as a Preclinical Researcher working in the Biotech/Pharmaceutical industry. • Strong technical abilities and knowledge working with a variety of research models and samples analysis utilizing a wide range of lab equipment. • Team player who excels at building trusting relationships across teams and who thrives in environments requiring ability to effectively prioritize and multitask concurrent projects.• Exceptional communicator who can convey information verbally and in writing.• Analytical thinker with the capability to refine and streamline processes to produce reliable and reproducible data, with a sense of urgency. • A professional whose honesty and integrity provide effective leadership and relationships with both colleagues and external collaborators. • Dependable, responsible contributor, committed to excellence and success. • Energetic performer consistently cited for having a sunny disposition, and upbeat, positive attitude• Major contributor in the design, construction, and management of a 3000 sqft Vivarium, followed by an additional 3000 sqft expansion 2 years later. • Generated protocols, data, and summaries for scientific publications, scientific meetings, and Investigational New Drug (IND) submissions. • Generated In Vivo data that helped support progressing two Novel Compound Entities (NCE’s) into human clinical trials and even approved to market (Labalvi). • Assisted Team in successfully obtaining Association for Assessment and Accreditation of Laboratory Animal Care (AAALAC) accreditation for Vivarium.• Served as IACUC representative, Company Values Team Leader, Public Awareness Leader, Activities Committee member, Alkermes in Action Team Leader, and many other volunteer roles where I thought I could help build a stronger teams outside of my own.
Neosome Life Sciences
View- Website:
- neosomels.com
- Employees:
- 5
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Study DirectorNeosome Life Sciences Jan 2024 - PresentBillerica, Massachusetts, United States -
ScientistAlkermes Jul 2022 - Aug 2023Wlatham, Ma• Developed techniques and procedures, write protocols, and execute studies both in the Vivarium and at the lab bench.• Trained team members and execute studies utilizing Automated In Vivo Sampling Systems, Electrolyte and Blood Gas Analyzers, EchoMRI Body Composition Analyzer, and WES/JESS for “blot free” Western Blots.• Ran POC studies in iPSC derived Human Neurons and various cell lines • Managed sample collections from ongoing studies and final takedowns (necropsy). • Developed sample preparation techniques to detect a variety of proteins from various tissues and brain regions. • Measured targeted proteins or “biomarkers” by Western Blot utilizing multiple protocols including JESS a “blot free” WB and more traditional gels with and the “iBlot” transfer system. • Processed tissue samples to isolate RNA and cDNA and run qPCR.• Administered drugs to rats via subcutaneous, intraperitoneal, intravenous, and oral gavage. • Ran rat Pharmacokinetic assays collecting blood samples via sublingual, submandibular. • Collected and analyzed data, generate statistics, construct graphs, and write reports.• Operated relative equipment such as the Odyssey Western Blot Scanner, Incucyte live cell imager, Opera Phenix Plus confocal imager, InvivO 300 Hypoxia Workstation, Nanostring nCounter Pro gene expression Analysis System, KingFisher Apex automated RNA purification system.• Active member of Talent, Engagement, and Innovation (TEI) “Rotations” Team developed to locate and offer internal on the job training opportunities for R&D employees in departments within Alkermes• EHS Safety leader CPR and AED trained. -
Scientist IAlkermes Jul 2016 - Aug 2022Waltham, Ma -
Senior Research AssociateAlkermes Jan 2013 - Jun 2016Waltham, Ma -
Senior Associate ScientistSirtris Pharmaceuticals, A Gsk Company Nov 2005 - Jun 2011• Scheduled and coordinated all in-house animal studies. • Wrote, reviewed, and served as Principal Investigator (PI) on all IACUC protocols.• Conducted pharmacokinetic, drug tolerance, and chronic dosing studies.• Prepared compound formulations, administered via subcutaneous, intraperitoneal, intravenous, oral gavage, and ICV.• Collected blood via tail, retro orbital, cardiac puncture.• Ran Insulin ELISA’s, Free Fatty Acid assay’s, Clinical Chemistry for various markers.• Maintained Vivarium; mouse orders, sentinel program, supplies, tissue bank• Presented analyzed data, generated statistics, constructed graphs and Power Point presentations.• Served as point person for multiple offsite collaborations and contractors. • Assisted in locating, evaluating, and securing Vivarium space. • Designated and equipped Animal Holding and Procedure rooms.• Managed team of 6 Research Assistants • Mouse Models of metabolic disorders, Cisplatin induced Kidney Injury, LPS induced TNFα release. -
Senior Research AssociateEnvivo Pharmaceuticals Dec 2003 - Nov 2005• Neurodegenerative Mouse Models R6/2 HD, Quinolinic Acid, 3-NP Striatal lesion HD.• Administered drugs to mice via subcutaneous, intraperitoneal, intravenous, oral gavage, and ICV.• Performed Stereotaxic Surgery; Intracerebroventricular (ICV) and Intrastriatal injections.• Conducted RotaRod behavioral studies, PK/PD, tolerance and chronic dosing studies.• Prepared compound formulations for ongoing studies.• Maintained Vivarium; mouse orders, Sentinel program, supplies, lab supplies and equipment.• Prepared mouse tissues and performed BCA Protein and HDAC activity assays. • Wrote IACUC protocols.• Assisted in locating, evaluating and securing Vivarium space. • Designated and equipped Animal Holding and Procedure rooms.• Trained and directed three Research Assistants on lab bench techniques and surgical procedures. -
Research AssociateAls-Tdi Oct 2002 - Dec 2003• Neurodegenerative Mouse Models research SOD1 ALS mouse model.• Performed Chronic dosing studies monitoring disease progression via multiple routes of administration.• Performed Stereotaxic Surgery; placement of ICV cannula for continuous delivery of drug via mini-pump.• Collected mouse tissues and blood plasma for outsourcing; spinal cord, whole brain.• Performed ELISA and Western Blots.• Served as IACUC representative.• Managed shipping and receiving of biological waste and cataloged MSD Sheets for drug and chemical library.• Assisted with moving Company to new location.• Trained staff on communication of company mission statements to the public. -
Research AssistantEukarion Inc. May 2000 - Aug 2002• Conducted experiments and surgeries on balb/c and hrs/jhr (hairless) Mice, and Sprague Dawley Rats.• Administered drugs to mice and rats and collected blood via tail vein and cardiac stick.• Assisted in Rat Stroke Model experiments; pre and post-surgery procedures.• Maintained Vivarium; ordering animals and material, animal husbandry. • Trained research professionals from BU and UMASS in surgical procedures for subcutaneous ALZET pump implantation.• Maintained several cell lines and performed cell membrane permeability screening and fluorescent labeling of cells.• ELISA, BCA Protein Assay, TCA Precipitation of radio-labeled Ab.• Operated Microplate reader, Spectrometer, and Scintillation counter.
David Gagne Skills
David Gagne Education Details
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Engineering -
Biotechnology
Frequently Asked Questions about David Gagne
What company does David Gagne work for?
David Gagne works for Neosome Life Sciences
What is David Gagne's role at the current company?
David Gagne's current role is Study Director at NeoSome Life Sciences.
What is David Gagne's email address?
David Gagne's email address is pu****@****hoo.com
What schools did David Gagne attend?
David Gagne attended University Of Massachusetts Lowell, Middlesex Community College.
What are some of David Gagne's interests?
David Gagne has interest in Football, Exercise, Sweepstakes, Nascar, Home Improvement, Reading, Gourmet Cooking, Sports, Watching Auto Racing, Watching Basketball.
What skills is David Gagne known for?
David Gagne has skills like In Vivo, Biotechnology, Pharmacology, In Vitro, Elisa, Drug Discovery, Western Blotting, Animal Models, Cell Culture, Research, Tissue Culture, Toxicology.
Who are David Gagne's colleagues?
David Gagne's colleagues are Laxman Desai, Joanne Miller, Stephanie Fedorchak, Sara Little, Margaret O'connor.
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