Management of Company-Sponsored Clinical Trials at the Site Level:• Phase III studies Oncology • Phase III studies Hemato-Oncology • Phase III studies Immunology-Inflammation• Phase IV study Hemato-Oncology Key Responsibilities:• Performing Initiation, Monitoring and Closeout visits (remote and on-site) per monitoring plan• Supporting study start-up activities• Providing protocol and related study training to assigned site staff• Supporting site to… Show more Management of Company-Sponsored Clinical Trials at the Site Level:• Phase III studies Oncology • Phase III studies Hemato-Oncology • Phase III studies Immunology-Inflammation• Phase IV study Hemato-Oncology Key Responsibilities:• Performing Initiation, Monitoring and Closeout visits (remote and on-site) per monitoring plan• Supporting study start-up activities• Providing protocol and related study training to assigned site staff• Supporting site to enhance patient recruitment and retention• Ensuring management and resolution of site issues• Managing site performance by tracking recruitment, eCRF completion and query resolution• Ensuring CTMS, eTMF and eCRF accuracy• Reviewing and approving site payments• Mentoring, training and performing co-visits with juniors CRA Show less

Ph.D. projects:• Study of the anti-leukemic role of Natural Killer (NK) cells in the context of haploidentical hematopoietic stem cell transplantation• Study of the impact of the KIR and HLA genotypes on the ADCC responses of the KIR NK cell populations induced by RituximabMain activities and achievements:• Management and accomplishment of research projects • Development and optimization of experimental methods that led to the identification of NK cell populations with… Show more Ph.D. projects:• Study of the anti-leukemic role of Natural Killer (NK) cells in the context of haploidentical hematopoietic stem cell transplantation• Study of the impact of the KIR and HLA genotypes on the ADCC responses of the KIR NK cell populations induced by RituximabMain activities and achievements:• Management and accomplishment of research projects • Development and optimization of experimental methods that led to the identification of NK cell populations with high anti-leukemia potential• Strategic planning, organization and execution of experimental procedures• Collection, processing and critical analysis of scientific data• Extensive review of the scientific literature on NK cell biology, immunology/immuno-oncology and hematology/onco-hematology• Management of 2 trainees: 1 Italian master's degree student for 6 months and 1 master's degree for 2 months.Scientific communications:• Technical writing: Contribution to the writing of scientific papers (4 publications)• Attendance in national scientific congresses: Exhibition of 2 posters at the annual meeting of the French Society for Immunology in 2019; 1 oral communication and exhibition of 2 posters at the Scientific Days 2019 organized by the Doctoral School of Health Biology of Nantes University.• Presentation of scientific data during internal and external team meetings Technical approaches used:• Cell biology: Leukemia Cell line cultures; Isolation of PBMC and human primary leukemia cells• Molecular biology: DNA extraction, gel electrophoresis, PCR–Sequence Specific Primer (genotyping)• Immunological cell-based assays: Degranulation, ADCC, Cytotoxicity, Cell stimulation...• Advanced Antibody Panel Design for Multiparametric Flow Cytometry/FACS• Bioinformatics: FlowJo, Diva, GraphPaD Prism, Genesis Show less

Research project: « Study of molecular interactions participating in the anti-leukemic role of Natural Killer (NK) cells in the context of haploidentical hematopoietic stem cell transplantation»Main activities and achievements:• Management and execution of a research project leading to the Industrial Agreementfor Training through Research grant for the doctorate (3 years)• Design, planning, organization and execution of experimental procedures• Data collection… Show more Research project: « Study of molecular interactions participating in the anti-leukemic role of Natural Killer (NK) cells in the context of haploidentical hematopoietic stem cell transplantation»Main activities and achievements:• Management and execution of a research project leading to the Industrial Agreementfor Training through Research grant for the doctorate (3 years)• Design, planning, organization and execution of experimental procedures• Data collection, processing and critical analysis• Coordination with team members to ensure the smooth progress of the project• In-depth review of the scientific literature on NK cell biology, immunology / immuno-oncology and hematology / onco-hematologyScientific communications:• Presentation of scientific data during internal meetings• Writing a master’s degree research dissertation• Oral presentation of master’s degree research results in English in front of expert jury Show less

Research project: "Central regulation of energy homeostasis by the nuclear receptor FXR: implication of neurogenesis"• Set-up and optimization of an Immunostaining method for mouse brain sections• Image analysis by fluorescence microscopy and confocal microscopyScientific communications:• Writing a master's research dissertation• Oral presentation of research results in front of an expert juryTechnical skills :• Scientific knowledge: type 2 diabetes… Show more Research project: "Central regulation of energy homeostasis by the nuclear receptor FXR: implication of neurogenesis"• Set-up and optimization of an Immunostaining method for mouse brain sections• Image analysis by fluorescence microscopy and confocal microscopyScientific communications:• Writing a master's research dissertation• Oral presentation of research results in front of an expert juryTechnical skills :• Scientific knowledge: type 2 diabetes, obesity, energy metabolism• Immunohistochemistry, immunofluorescence• Animal experimentation Show less

Research project: « Study of the spectrum of antiviral activity of a biological sample »• Planning and execution of experimental procedures• Bibliographic research on the Human B4 Coxsakievirus and type 1 diabetesScientific communications:• Writing an internship report• Oral presentation of internal research resultsTechnical skills :• Scientific knowledge: Virology, Enterovirus, type 1 diabetes• Cell biology: culture of established lines, viral… Show more Research project: « Study of the spectrum of antiviral activity of a biological sample »• Planning and execution of experimental procedures• Bibliographic research on the Human B4 Coxsakievirus and type 1 diabetesScientific communications:• Writing an internship report• Oral presentation of internal research resultsTechnical skills :• Scientific knowledge: Virology, Enterovirus, type 1 diabetes• Cell biology: culture of established lines, viral infection of cells• Virology: study of the cytopathogenic effect of viruses by seroneutralization tests Show less