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As a Senior Scientist with extensive experience in preclinical and translational research within the biomedical and pharmaceutical sectors, I have developed a strong foundation in organizational, project management, and execution skills throughout my career. My expertise encompasses a broad range of preclinical drug discovery research, including the development of innovative strategies and technologies for target identification, validation, and assay development. I am now poised to take on higher-level roles that come with additional responsibilities, where I can apply my decade-long experience to drive research initiatives, mentor emerging scientists, and contribute to the strategic growth of the organization.
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Scientist, DiscoveryOligomerix, Inc Oct 2022 - PresentWhite Plains, New York, UsAs a Scientist at Oligomerix, Inc., I utilize my excellent laboratory skills and a strong background in neurobiochemistry and neuropharmacology to jump start and lead a small preclinical in vivo research team in an incubator lab located at Albert Einstein College of Medicine, Bronx, NY. The primary duties involve designing and executing invivo experiments for projects focused on validating and characterizing the preventive and therapeutic effect of selected drug candidates in various mice models of Alzheimer’s disease and related tauopathies. In addition, I routinely engage in internal and external collaborative efforts to move forward the ongoing projects and in process acquire an extensive experience in various aspects of preclinical drug discovery and development.
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Postdoctoral AssociateOligomerix, Inc Jan 2020 - Oct 2022White Plains, New York, UsAt Oligomerix, I lead and assisted several preclinical in vivo projects that are targeted towards characterizing and validating small molecules and biomarkers specific for tau fragments to accelerate our efforts in developing a small molecule inhibitor of tau self-association, an initial step of tau aggregation cascade that progresses to devastating neurodegeneration.Present job responsibilities:Designed and executed preclinical research plans integrating both disease and pathway approaches to support the company's small molecule program. Identified and utilized relevant invitro and invivo models to develop methods evaluating the biomarkers and mechanism of action of company’s lead drug candidates. Proposed and executed biomarker strategies for target engagement, and pharmacodynamic endpoints of the company's lead drug candidate. Oversaw and worked closely with research associates to manage the execution of their assigned research task.Performed detailed research data analyses and reporting of study readouts both internally and at scientific conferences.
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Doctoral CandidateRush University Sep 2014 - Nov 2019Chicago, Il, UsDeveloped and characterized transgenic animal models of Alzheimer's disease (AD) that help discern the neuro-protective role of nuclear receptor protein in AD based dementia.Conducted preclinical studies to evaluate motor functions in a mouse model of Parkinson's disease developed using cre lox system.Identified and repurposed the known FDA approved drugs as potential therapeutic candidate for treating cognitive impairment using transgenic animal models of AD. Acquired extensive experience in mouse genetics, in vivo rodent models, rodent organ dissections & molecular biology and SOFTWARES such as - Noldus software, PRISM graph pad, Genomatix software suite for transcription factor binding analysis, MS office (Word, excel, powerpoint) and Adobe Photoshop -
Cellular And Molecular Biology TutorHudson County Community College Jan 2013 - Aug 2014Nj, UsTutoring Services at Hudson County Community College is a centrally organized program which coordinates free, drop-in, peer tutoring in many subject areas and centers on main campus. All tutoring is free to currently enrolled Lane students and provides one-on-one assistance in most academic subjects.My role as Cellular and Molecular Biology Tutor was to serve students enrolled in credit courses related to cell biology,human anatomy and physiology I & II, nutritional sciences and chemistry, by providing supportive learning environments, instilling confidence, encouraging independence as learners, and providing individual peer tutorial assistance and academic support. -
Laboratory TechnicianSt John'S University Oct 2011 - Aug 2012Queens, Ny, UsPrepared recombinant plasmid DNA for target identification research and carried out experiments in yeast molecular biology. Mastered hands on experience in techniques that include, but are not limited to: gel electrophoresis, real time PCR, RT-PCR, immunoblotting, confocal microscopy, and transformation of bacterial and yeast cells. -
Research Intern In Obesity, Muscle And Metabolic GroupRegeneron Pharmaceuticals Sep 2010 - Aug 2011Tarrytown, New York, UsDuring my tenure at Regeneron Bio Pharmaceuticals Inc, Tarry town NY assisted the Staff Scientist to investigate the role and activity of potential targets against metabolic disorders like Diabetes, hyperlipidemia and cardio vascular diseases.Identified and validated new targets for Obesity and Metabolic Disease group.Implemented and populated a repository for molecular biology reagents that include, plasmid clones, maxipreps and glycerol stocks of DNA clones and sequencing primers.Expedite the tracking for every reagent by creating excel based database which also contained relevant information for each of the reagent. Manufactured plasmid clones and viral clones and optimized the screening of positive clones through restriction digestion analysis and DNA sequencing.Amplified cloned plasmid DNA through bacterial transformation and performed high throughput DNA isolation using Vacuum manifold protocol and 96well format DNA isolation. Analyzed protein expression and activity of the clones, through immunochemical assays like SDS PAGE and western blotting.Characterized antibodies and used them in developing functional cell based assays to screen activity and localization for new targets. -
Quality Control And Research AssociateHamax Pharmaceutical, Vadodara, Gujarat, India Mar 2008 - Nov 2008Worked in Research, Development and Quality Assurance Department, performed pre clinical, Pre-formulation and Dissolution studies. Underwent extensive training on various aspects of Quality Compliance, Regulatory and Clinical Practices (FDA, ICH) required to produce an effective, safe, compliant and ready- to- market product. Assisted in preparing and reviewing, quality plans (GMP, GLP),validation protocol (SOP) and auditing procedures.
Dhruv Patel, Ph.D. Skills
Dhruv Patel, Ph.D. Education Details
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Rush UniversityBiochemistry (Neuro Track) -
Hudson County Community CollegeAssociate'S Degree In Management (Few Credits Remaining)
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St. John'S UniversityMaster'S Degree In Biological And Pharmaceutical Biotechnology
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Rajiv Gandhi University Of Health SciencesBachelor'S Degree In Pharmaceutical Sciences
Frequently Asked Questions about Dhruv Patel, Ph.D.
What company does Dhruv Patel, Ph.D. work for?
Dhruv Patel, Ph.D. works for Oligomerix, Inc
What is Dhruv Patel, Ph.D.'s role at the current company?
Dhruv Patel, Ph.D.'s current role is Scientist at Oligomerix Inc., NY USA.
What is Dhruv Patel, Ph.D.'s email address?
Dhruv Patel, Ph.D.'s email address is dh****@****ush.edu
What is Dhruv Patel, Ph.D.'s direct phone number?
Dhruv Patel, Ph.D.'s direct phone number is +131294*****
What schools did Dhruv Patel, Ph.D. attend?
Dhruv Patel, Ph.D. attended Rush University, Hudson County Community College, St. John's University, Rajiv Gandhi University Of Health Sciences.
What are some of Dhruv Patel, Ph.D.'s interests?
Dhruv Patel, Ph.D. has interest in Science And Technology, Education, Disaster And Humanitarian Relief.
What skills is Dhruv Patel, Ph.D. known for?
Dhruv Patel, Ph.D. has skills like Western Blotting, Sds Page, Elisa, Pcr, Protein Chemistry, Tissue Culture, Protein Purification, Molecular Biology, Primer Design, Cell Biology, Protein Expression, Bacterial Transformation.
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