- Principal Investigator on NIH U24 Project "DataJoint Pipelines for Neurophysiology."- Led research and development of scientific computing frameworks and platforms.- Led business development efforts to define technological approaches, products and services to address the needs of scientific communities.- Developed partnerships with technology providers, standards and advocacy groups, and academic partners.- Defined and executed the company's intellectual property policy. - Generated grant proposals and defining new projects.- Developed communications about the company's products and services. Publishing white papers, scientific papers, articles, and educational materials.

* Co-founded Vathes LLC (which became DataJoint in 2021). Established the company governance and operations, vision and mission. * Proposed and led the implementation of the SBIR Phase I project to validate the commercialization potential of the DataJoint software framework and accompanying services for neuroscience research. Negotiated with research teams to define contracts and statements of work. * Wrote proposals and built teams for shared computational pipelines for neuroscience data analysis.

Contributed to NSF grant proposal and to project planning. Defined the Machine Learning framework for real-time surgical imaging and navigation: https://doi.org/10.1117/12.2293766. Developed motion correction algorithms. Consulted on x-ray dose calculations.

Studied functional connectivity in cortical microcircuits. Developed statistical methods for inferring the functional connectivity from recordings of neural population activity.

Managed a project to develop a wearable epileptic seizure detector. Developed a novel epilpetic seizure detector algorithm. Developed a myolectric control scheme for upper limb prosthetics.Co-authored federal research grant proposalsMediated collaborations with academic and government research partners.

Led a team of engineers in simulation and design requirement specification, verification, and validation of surgical x-ray imaging and navigation systems. This included GE OEC 9900 Elite, GE OEC 2800, GE OEC 6800.My primary focus was on automated x-ray dose management and image quality performance, image processing, image reconstruction, and workflow for varied use profiles: cardiac catheterization, electrophysiology, vascular, and orthopedic applications.Led the simulation, design specification, and design validation of an FPGA-based image processor for real-time surgical imaging. These processors and associated applications have been deployed into production and are used in hundreds of operating rooms around the world. Designed and optimized feedback-controlled x-ray exposure management subsystems, x-ray spectral filters, and adaptive x-ray beam modulation devices.Produced six patented inventions, awarded the “Best GE Healthcare Surgery Patent” award in 2004.

Developed MS Windows drivers for a 2D barcode reader to enable Internet hyperlinks in printed media. The drivers provided communication between the device (barcode reader) and Internet applications on the host.

Developed public safety software applications: distributed database access, street navigation algorithms.