Dipen Soni Email & Phone Number

Toronto, On, Ca

Toronto, Ontario, Canada

Toronto, Canada Area

• Responsible for performing protein purification from start to end for five protein-based antigens using multiple techniques such as centrifugation, chromatography, and ultrafiltration in a cGMP environment, following standard operating procedures (SOPs);• Involved in Validation Mater Plan (VMP) project, for validation of new automated equipment in production environment, this involved going through steps such as IQ,OQ and PQ.• Led multiple projects in the department to increase efficiency using the Lean Six Sigma methodology / 5S;• Actively involved in the maintenance, authoring, and review of controlled documents such as standard operating procedures (SOPs);• Experienced creating and implementing effective change control requests (CCRs) and CAPAs using Phenix to streamline processes and improve safety in the department;• Supported deviation investigations via 6M approach for root cause analysis (RCA), interviewing individuals, and gathering evidence to determine the root cause and effective corrective and preventative actions (CAPAs);• Served as a Health, Safety and Environment (HSE) relay for the team, acting as a liaison for communicating information between HSE and production and participated in safety initiatives by escalating any potential hazards and helping to develop proposed solutions• As a qualified trainer on technical and non-technical processes, was responsible for organizing and conducting comprehensive training to the technical staff on process operations, facility cleaning procedures, cleanroom gowning in grade C and D areas, as well as the use of various corporate-based software;• Experienced with audits, having worked closely with the management team during regular inspections by FDA, Health Canada and other regulatory agencies;• Used SAP and SAP S4HANA ERP software extensivity in the production environment to perform batch characterization/releases, order new supplies up to $100,000, and creating new purchasing orders;

Toronto, Canada Area

•Execution of laboratory tests, including virus- and cell-based assays (e.g. viral propagation and titration)•Participation in special projects/ experiments/ continuous Improvement of existing tests, test transfer and validation.•Maintenance of completed laboratory records in specific electronic laboratory notebooks (LIMS), preparation of supportive document, and use of department databases.•Maintenance compliance of quality systems and laboratory including GMPs and HSE Guidelines.•Support for the design of studies, data interpretation, statistical evaluation and report writing as part of a team environment

London, Canada Area

• Focused on comparing genetic diversity genome wide after selection of fit phenotypes for wild-caught mice in natural environments compared to laboratory- housed inbred mice. In Addition, genome diversity genome wide was compared for breast cancer cells to lung metastasis cells in mice • The positive, negative or natural selection was calculated using diversity index at 493,270 single nucleotide polymorphisms(SNPs) loci in DNA, which was generated by mouse genotyping array• Participated in weekly meeting with professor and other research scientists from London Regional Cancer Research to further discuss on research project and resolve any issues• Poster and abstract on cancer research was presented at Windsor Region Cancer Conference. Also, attended London Regional Cancer Reserach Conference to gain further understanding of cancer research and bioinformatics• Attended computer classes to improve programming skills required for bioinformatics research

London, Canada Area

• Performed Enzyme-Linked Immunosorbent Assay (ELISA assay) and Nitric Oxide assay(NO) to determine the concentration of cytokine (TNFα, IL-IL-1β) production by macrophages• Carefully following aseptic procedures made macrophage cell culture and applied different treatments such as Lipopolysaccharide (LPS), Nanopure water, and different concentrations of Ginseng• Analyzed raw data using software such as Gen5 and Microsoft Excel to determine averages, to graph data and to determine significance of results• Participated in monthly meeting to gain further understanding of research project and resolving any issues regarding the lab • Completed general lab work such as polysaccharide extraction, labelling containers/tubes, performing serial dilutions, pipetting (multichannel and single), autoclaving and cleaning

London, Canada Area

• Trained to perform euthanization of mice and followed surgical procedures to dissect mice’s eyes and optic nerve for fixation and qualitative data were recoded by comparing control and mutant eyes• Practiced pipetting techniques using single and multichannel pipette and filled empty pipet boxes with tips for autoclaving• Washed and organized lab’s glass instruments with precaution and labelled tubes used for experiment• Participated in bimonthly meetings to understand the research and to complete lab trainings

London, Canada Area

• Received a training by Dr. Silber on how to perform a literature search on different types of articles, gaining access to paid papers from various sites and using the software (Mendeley) to save the work• Literature search on Moon was performed specifically considering for different types of craters and their impact• Worked as a team to solve any issue regarding the literature search such as gaining access to paid sources, troubleshooting the software and getting information required for citation

London, Canada Area

• Performed a basic health check for birds by observing their behaviour and interaction with other birds in their cage and carefully separating unhealthy birds to individual cages• Refilled the containers for food, water and rock in all the cages and washed the empty bird cages• Received a basic training to catch birds safely in case they escape from their cage

Toronto, Canada Area

• Worked with surgeons/nurses to prepare and observe the minor surgical process such as carpal tunnel, removal polydactyl from a baby, second degree burns, removal of various size of lumps, and removal of toe-nails• Acknowledged each patients personal need and patiently interacted with them by conversing and by serving food and fresh water, accordingly, relieving their emotional stress before surgery• Constantly listened to and followed nurse’s requests such as stocking the medical equipments used for surgery, followed the safety precaution and ensured the confidentiality • Operated in Emergency Department as first line of interaction with incoming patients and guiding them to proper locations

Bachelor Of Medical Sciences, Honors Specialization In Interdisciplinary Medical Sciences

Activities and Societies: Discovery Cafe, Foot Patrol, Research

96.3%

Activities and Societies: Robotic Club, Leadership Club, Eco- Club