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Divya Murthy, Phd Email & Phone Number
Assistant Professor at Department of Pathology and Laboratory Medicine
at
Brown University
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Role
Assistant Professor at Department of Pathology and Laboratory Medicine
Location
Providence, Rhode Island, United States
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Divya Murthy, Phd is listed as Assistant Professor at Department of Pathology and Laboratory Medicine at Brown University, based in Providence, Rhode Island, United States. AeroLeads shows a matched LinkedIn profile for Divya Murthy, Phd.
Divya Murthy, Phd previously worked as Staff Research Associate at Baylor College Of Medicine and Research Instructor at University Of Nebraska Medical Center. Divya Murthy, Phd holds Doctor Of Philosophy - Phd, Biotechnology from Institute Of Genomics And Integrative Biology (Csir).
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Brown University
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About Divya Murthy, Phd
As a Staff Research Associate at Baylor College of Medicine, I apply my PhD in Biotechnology and 7+ years of postdoctoral research experience in cancer biology to investigate the role of metabolites on the survival and aggressiveness of pancreatic cancer. My mission is to advance the understanding of tumor microenvironment-mediated metabolic reprogramming and identify novel therapeutic targets and biomarkers for this deadly disease.I have a strong background in molecular and cellular biology, proteomics, and metabolomics, with multiple peer-reviewed publications in diverse scientific journals. I am proficient in various techniques such as LC-MS/MS, RNA-Seq, CRISPR-Cas9, and Reverse Phase Protein Arrays. I am also skilled in scientific writing, communication, and collaboration, having authored and co-authored several manuscripts and worked with multidisciplinary teams. I am passionate about applying my knowledge and expertise to contribute to the field of cancer research and improve patient outcomes.
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8 roles
Divya Murthy, Phd work experience
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Assistant Professor At Department Of Pathology And Laboratory Medicine
Current
Sep 2024 - Present
Staff Research Associate
Mar 2022 - Aug 2024
Research Instructor
Apr 2020 - Feb 2022
Postdoctoral Research Associate
- Tumor microenvironment-mediated metabolic reprogramming in pancreatic cancer. I work on understanding the role of metabolites on the survival and aggressiveness of pancreatic cancer. My work deals with:
- Identification of metabolites by Liquid Chromatography based metabolomics (LC-MS/MS).
- Identification of genes that potentially promote an aggressive cancer phenotype in pancreatic cancer using Chromatin Immunoprecipitation and RNA-Seq
- Proteome analysis using mass spectrometry.
- Developing CRISPR-Cas9-based knockout models.Technical Skill set:
- Phospho-proteomic studies in pancreatic cancer cells using Reverse Phase Protein Arrays
Apr 2016 - Mar 2020
Graduate Student
- Understanding the melanosome and mitochondria dynamics during pigmentation.
- Delineated the role of autophagic machinery in melanosome biogenesis and degradation.
- Characterized a non-canonical role of autophagic protein MAP1LC3B in mediating movement of melanosomes during melanogenesis.
- Identified the motor protein (kinesin) that mediate translocation of melanosomes in melanocytes.
- Explored the melanosome-mitochondria crosstalk during melanogenesis using a compendium of tools and techniques including mass spectrometry, mammalian cell culture, and extensive confocal based microscopy.
- Utilized organotypic culture derived from human subjects for isolation of melanocytes to validate cell line-based findings.Technical Skill set:
Jul 2009 - Oct 2015
Collaborative Project
- Elucidating the role of PLEKHM2 in melanosome trafficking on cytoskeletal tracks in melanocytes.
- Collaborated on a research project to elucidate the role of the adaptor protein, PLEKHM2 (SKIP), in mediating movement of melanosomes within melanocyte.
- Performed exogenous overexpression and confocal-based experiments to study subcellular localization of PLEKHM2 on melanosomes.
- Extensively employed microscopy to analyze subcellular organelles and structures, and live cell imaging to understand organelle dynamics and kinetics.https://www.biorxiv.org/content/10.1101/2021.03.11.434917v1
Mar 2014 - May 2014
Master Student
- Cytokine expression profiling in Caco-2 and RAW 264.7 cell lines exposed to Lactobacilli isolates to evaluate their probiotic effect.
- The project aimed at understanding the modulation in the cytokine profiles of pro- and anti-inflammatory cytokines in Caco-2 colon carcinoma cell lines and RAW 264.7 macrophage cell lines stimulated with various.
- Isolated various Lactobacilli strain from different sources, stimulation of Caco-2 and RAW 264.7 cell lines with the Lactobacilli isolates.
- Performed bacterial adhesion assays and semi-quantitative PCR-based cytokine profiling.The project yielded interesting findings. I observed significant immunomodulation on stimulation with various Lactobacilli isolates.
- Mammalian cell culture, semi-quantitative PCR, bacterial adhesion assays.
Jul 2007 - Apr 2009
4 education records
Divya Murthy, Phd education
Doctor Of Philosophy - Phd, Biotechnology
Master'S Degree, Biotechnology
Bachelor'S Degree, Biochemistry
Higher Secondary Education, Cbse
St. Marks Sr Sec Public School, New Delhi
FAQ
Frequently asked questions about Divya Murthy, Phd
Quick answers generated from the profile data available on this page.
What company does Divya Murthy, Phd work for?
Divya Murthy, Phd works for Brown University.
What is Divya Murthy, Phd's role at Brown University?
Divya Murthy, Phd is listed as Assistant Professor at Department of Pathology and Laboratory Medicine at Brown University.
Where is Divya Murthy, Phd based?
Divya Murthy, Phd is based in Providence, Rhode Island, United States while working with Brown University.
What companies has Divya Murthy, Phd worked for?
Divya Murthy, Phd has worked for Brown University, Baylor College Of Medicine, University Of Nebraska Medical Center, Institute Of Genomics And Integrative Biology (Csir), and Goethe University Frankfurt.
How can I contact Divya Murthy, Phd?
You can use AeroLeads to view verified contact signals for Divya Murthy, Phd at Brown University, including work email, phone, and LinkedIn data when available.
What schools did Divya Murthy, Phd attend?
Divya Murthy, Phd holds Doctor Of Philosophy - Phd, Biotechnology from Institute Of Genomics And Integrative Biology (Csir).
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