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David L. Email & Phone Number

Senior Director, Analytical Development, Kezar at Exelixis
Location: Pleasanton, California, United States 12 work roles 3 schools
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Current company
Exelixis
Role
Senior Director, Analytical Development, Kezar
Location
Pleasanton, California, United States
Company size
51 employees

Who is David L.? Overview

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David L. is listed as Senior Director, Analytical Development, Kezar at Exelixis, a company with 51 employees, based in Pleasanton, California, United States. AeroLeads shows a matched LinkedIn profile for David L..

David L. previously worked as Sr. Director, Analytical Chemistry at Exelixis and Senior Director, Analytical Developent at Kezar Life Sciences. David L. holds Ph.D, Organic Chemistry from Washington University In St. Louis.

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Exelixis

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Profile bio

About David L.

Senior Director and Department Head of Analytical Development at Kezar Life Sciences.Director and Department Head, Analytical Development, responsible for departmental strategic planning, departmental budgeting, communication with executives, resource and people management, project management, CDMO management, and regulatory filings; also responsible for all aspects of analytical development and analytical controls of four active clinical programs of oncology of NurixGilead Analytical Operations (AO) Lead for two NASH programs representing AO in the PDM Subteam and responsible for all analytical needs in the programs including method development, method validation, or method transfer, specifications, release testing, and stability studies of drug substance and drug product, OOT/OOS investigations, CMO/CRO management, and regulatory filing authoringAward-winning chemist with a solid background and in-depth knowledge of analytical development, organic chemistry, bioconjugation, surface chemistry, solid-state characterization (XRPD, DSC, TGA, FTIR, Raman, etc.), fluorescence, chemiluminescence, bioluminescence, and nanotechnologiesStrategic thinker with excellent communication skills and people skills Track record of scientific achievements as evidenced by over 50 publications and patents.

Current workplace

David L.'s current company

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Exelixis
Exelixis
Senior Director, Analytical Development, Kezar
South San Francisco, CA
Website
exelixis.com
Employees
51
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12 roles · 28 years

David L. work experience

A career timeline built from the work history available for this profile.

Sr. Director, Analytical Chemistry

Current
Exelixis

Alameda, California, US

Oversee analytical development of multiple oncology programs including antibody-drug conjugates (ADC) and small molecule anticancer drugs.

Mar 2024 - Present

Senior Director, Analytical Developent

Current
Kezar Life Sciences

South San Francisco, California, US

Kezar, winner of “The Best Place to Work in Bay Area”! Head of Analytical Development responsible for all aspects of analytical control of Kezar clinical programs and pre-clinical programs including KZR-616 for Injection (selective immunoproteasome inhibitor), KZR-261 (protein secretion inhibition, immuno-oncology), and KZR-540 (potent small molecule PD-1.

Mar 2023 - Present

Director, Analytical Development

Nurix Therapeutics

San Francisco, CA, US

Director, Analytical Development of CMC, Nurix, a biopharmaceutical leader in protein modulation for oncology: In charge of analytical controls of 4 clinical programs (NX-2127, NX5948, NX-1607, and NX-0255) from API to drug product to regulatory filings; Also responsible for departmental strategic planning, CDMO management, resources, and budget.

Apr 2021 - Mar 2023

Senior Scientist I

Gilead Sciences

Foster City, CA, US

Analytical Operations (AO) Lead for GS-8662, a second generation acetyl-CoA carboxylase inhibitor, ACCi.Analytical Operations (AO) Lead for Firsocostat (GS-0976, acetyl-CoA carboxylase inhibitor, ACCi), a key component of Gilead NASH franchise managing all analytical aspects of the project ranging from drug substance to drug product: Phase 3 method.

Nov 2018 - Mar 2021

Research Scientist Ii

Gilead Sciences

Foster City, CA, US

Analytical Operations (AO) Lead for ACCi (Acetyl-CoA Carboxylase inhibitor) arm of Gilead NASH Project including single agent and combos; Member of Analytical Core Team (ACT), Analytical Operations Department of Gilead Pharmaceutical Development & Manufacturing (PDM); Method development/validation/transfer, stability studies, OOS/OOT investigations, phase.

May 2016 - Nov 2018

Analytical Chemist

Gilead Sciences

Foster City, CA, US

Joined the most exciting pharmaceutical company in the world just for its amazing science, technology and products; Developed various analytical methods for in-process control (IPC) of API manufacturing and Fate & Purge studies.

Mar 2015 - May 2016

Co-Founder And Chief Scientific Officer

Heliosense Biotechnologies, Inc.

Co-Founded Heliosense Biotechnologies, Inc. Raised millions of RMBs from government agencies and private investors. In charge of company-wide R&D efforts as well as product development. Led the development of products including chemiluminescent immunoassay kits for diagnostics and affinity-based bioseparation products for biopharmaceutical industry

Apr 2011 - Mar 2015

Senior Researcher

Intel Corporation

In charge of sequencing chemical reagents for the Next Generation Sequencing (NGS) Project of Intel Labs. Co-Invented a series of nucleotide analogues including reversible terminators and terminally redox-labeled nucleoside oliophosphates (dNXP, X = 4 or 5) critical to Intel's NGS Project. Other projects involved include ultrasensitive detection of protein.

Dec 2005 - Apr 2011

Staff Scientist

Promega Biosciences

Madison, WI, US

Co-inventor for a powerful luminogenic detection technology that has been widely used in pharmaceutical companies to assay important enzymes such as cytochrome P450s. It was based upon a dual-enzyme detection system that makes use of luminogenic compounds (luciferin derivatives). The target enzyme acts on luminogenic compounds releasing luciferin, which in.

May 2003 - Dec 2005

Staff Scientist

Quantum Dot Corporation

US

Surface-modification, bioconjugation of quantum dots and their application in bio-medicine and life sciences; Had the honor to work with Professor Moungi Bawendi who was our scientific advisor and has won 2023 Nobel Prize in Chemistry.

Jan 2001 - Apr 2003

Postdoctoral Fellow

Washington University In St. Louis

St. Louis, MO, US

Diblock copolymers, polymeric nanomaterials, bioconjugations and their biological applications

1999 - 2000 ~1 yr
Team & coworkers

Colleagues at Exelixis

Other employees you can reach at exelixis.com. View company contacts for 51 employees →

SP Surender Patlori Surender Patlori Colleague at Exelixis Fremont, California, United States, United States View → RE Reyhaneh E. Reyhaneh E. Colleague at Exelixis San Francisco Bay Area, United States View → AY Andersen Yun Andersen Yun Colleague at Exelixis South San Francisco, California, United States, United States View → RK Rohit Kumar Rohit Kumar Colleague at Exelixis Newark, California, United States, United States View → SS Sharmila Sharmila Sharmila Sharmila Colleague at Exelixis San Francisco, California, United States, United States View → BD Beverly D. Abbott Beverly D. Abbott Colleague at Exelixis Greater Houston, United States, United States View → PD Pallavi D Pallavi D Colleague at Exelixis Atlanta, Georgia, United States, United States View → DG Dorian Grey Dorian Grey Colleague at Exelixis Ukraine, Ukraine View → MC Mi Chen, Phd Mi Chen, Phd Colleague at Exelixis San Francisco Bay Area, United States, United States View → JE Jean-Rene Ella-Menye Jean-Rene Ella-Menye Colleague at Exelixis Sacramento, California, United States, United States View →
3 education records

David L. education

Ph.D, Organic Chemistry

Washington University In St. Louis

Master Of Science (Ms), Organic Chemistry

Chinese Academy Of Sciences

Bs, Organic Chemistry

Peking University
FAQ

Frequently asked questions about David L.

Quick answers generated from the profile data available on this page.

What company does David L. work for?

David L. works for Exelixis.

What is David L.'s role at Exelixis?

David L. is listed as Senior Director, Analytical Development, Kezar at Exelixis.

Where is David L. based?

David L. is based in Pleasanton, California, United States while working with Exelixis.

What companies has David L. worked for?

David L. has worked for Exelixis, Kezar Life Sciences, Nurix Therapeutics, Gilead Sciences, and Heliosense Biotechnologies, Inc..

Who are David L.'s colleagues at Exelixis?

David L.'s colleagues at Exelixis include Surender Patlori, Reyhaneh E., Andersen Yun, Rohit Kumar, and Sharmila Sharmila.

How can I contact David L.?

You can use AeroLeads to view verified contact signals for David L. at Exelixis, including work email, phone, and LinkedIn data when available.

What schools did David L. attend?

David L. holds Ph.D, Organic Chemistry from Washington University In St. Louis.

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