Denis Kole, Ph.D. Email & Phone Number

Boston, MA, US

Global, Global, OO

Port Washington, New York, US

Bridging the gap between R&D and commercial manufacturing for gene and cell therapy processes. Helping accelerate cell and gene therapies' speed to patients through bench-scale process optimization, process simplification, and process scalability to commercial manufacturing scale.

Port Washington, New York, US

The Accelerator Process Development Services group offers design & optimization services for gene therapy, vaccine and monoclonal antibody production. Our team specializes in designing, optimizing and transferring scalable processes from pre-clinical to commercial manufacturing scale.

Port Washington, New York, US

Our exceptional team of SMEs provides expert support on technical training and implementation of continuous bioprocessing solutions at customer sites. We engage with customers and regulatory bodies such as the US-FDA to define regulatory expectations and concerns for implementation of integrated, continuous bioprocessing approaches.

Port Washington, New York, US

Integrated part of the Scientific Laboratory Services team supporting internal and external activities focused on implementation of Integrated, Continuous Bioprocessing Processes. Heavily operating in the areas of technology training, process support and new product development activities for downstream solutions.

North Chicago, Illinois, US

Part of an integrated team within the Abbvie Global Biologics group providing dedicated support to the Abbvie-Calico collaboration, leading research on aging and age-related diseases. A core project team member responsible for coordinating internal and external project team activities across functions. I led the efforts for the establishment of an in-vitro.

Worcester, Massachusetts, US

Responsible for the advancement of several projects with direct involvement in idea conception and development, securing funding, experimental design and hands on work at the bench. Development of a cell-derived extracellular matrix with antimicrobial properties. Role: Co-Principal InvestigatorNSF-STTR awardInvestigation of cell isolation methods and.

Worcester, Massachusetts, US

Dissertation: Role of Fibroblast Growth Factor 2 (FGF2) in Maintenance of Multipotency in Human Dermal Fibroblasts Treated with Xenopus Laevis Egg Extract Fractions

Managed a group laboratory technicians and was responsible for overseeing all technical operations related to recombinant protein expression in bacteria and yeast expression systems, from 50ml to 50L scale.

Responsible for planning, designing and executing protein purification and characterization processes for drug discovery targets. Additional responsibilities included training new team members and managing customer technical interactions.

Responsible for the execution of bench scale work supporting gene cloning and laboratory scale protein expression and purification activities.

Doctor Of Philosophy (Ph.D.), Biology And Biotechnology

Certificate In Graduate Business Study, Management And Entrepreneurship

Bachelor Of Arts - Ba, Biology, Chemistry Minor