Denis Malyshev Email & Phone Number

California, United States

San Diego, California, United States

eGlint is pioneering an innovative platform for rapid biomarker quantification. By providing clinicians with real-time cytokine readouts, eGlint addresses a crucial need in critical care settings, where timely interventions can significantly impact patient outcomes. Our platform offers unparalleled speed, accuracy, and cost-effectiveness, revolutionizing.

San Diego, California, United States

Technical and business consulting within the biotech and pharmaceutical sector provides specialized support and expertise to early and mid-stage companies. These services are designed to assist with the intricacies of fundraising, platform and product development, operational support, market strategy formulation, and integrating the voice of customers and.

Greater San Diego Area

San Diego

Acquired by PacBio for $600M plus milestones. I led the team that developed the most accurate sequencing biochemistry.

La Jolla

• Acquired by Sanofi for $2.5BNASDAQ ticker: THOR
• Enabled core platform technology for incorporation of multiple unnatural amino acids into proteins using an expanded genetic alphabet.
• Assisted in raising VC and non-dilutive funding.
• Established the laboratory space and developed the capabilities to implement the research program.
• Initiated and managed several collaborations with multiple global CROs.

Greater St. Louis Area

• Scientific and Market Life Science Advising (scimals.com) is a non-profit organization that provides pro bono scientific and market due diligence for early stage life science investors and entrepreneurs.
• Carried out market analyses on the pharmaceutical and cosmeceutical industries and wrote market reports for VC and angel investors evaluating an investment opportunity into a startup companies.
• Interviewed physicians to collect the information about market adoption of new drugs and cosmeceuticals.

La Jolla, CA

• Advisor: Floyd E. Romesberg, PhD
• Constructed a semi-synthetic organism that is capable of replicating unnatural genomic information thus establishing a six-letter expanded genetic alphabet of life.
• Demonstrated functional equivalence of an unnatural base pair to natural counterparts in PCR by studying sequence bias in the unnatural DNA libraries via bioinformatic analysis of deep sequencing data.
• Developed several applications that use an expanded genetic alphabet such as PCR, site-specific nucleic acid labeling with small and macromolecules, in vitro selection of DNA enzymes.
• Led the structural studies of DNA polymerase and DNA with an unnatural base pair that provided a clue to how natural and unnatural base pairs are replicated.

Moscow, Russian Federation

• Advisor: Valentin P. Ananikov, PhD
• Demonstrated that easily accessible nickel chloride is an efficient catalyst for the addition reaction of thiols and selenols to alkynes instead of the expensive and toxic phosphine complexes of palladium and platinum.
• Studied in detail the mechanism of the addition reaction and utilized the data to develop a robust, scalable and cost-effective catalytic system for the synthesis of vinyl sulfides and selenides. These compounds are.

Greater Chicago Area

• Advisor: Professor Vladimir Gevorgyan
• Developed and optimized Sila-Baylis-Hillman reaction with silylcyclopropenes.

Greater Chicago Area

• Advisor: Professor Rustem F. Ismagilov
• Initiated catalytic oxidation of methane in a microfluidic system.
• Synthesized a histidine-tag receptor for membrane protein crystallization trials.

Moscow, Russian Federation

Analyzed and wrote a report on the clean coal technologies for the Russian Ministry of Energy.

Glasgow, United Kingdom

• Advisor: Professor Pavel Kočovský
• Designed and developed a vanadium catalyzed asymmetric epoxidation of allylic alcohols.
• Participated in the development of the organocatalytic aldol reaction catalyzed by natural amino alcohols.

Greater New Orleans Area

• Advisor: Professor Steven P. Nolan
• Developed an efficient catalytic system based on transition metal carbene complexes for thiol addition to alkynes.
• Carried out mechanistic studies by NMR monitoring and isolated active catalytic species.
• Initiated efforts toward a Pd-catalyzed ketone arylation reaction under mild conditions.

Doctor Of Philosophy (Phd), Chemical Biology

University Diploma With Honors (M.S. Equivalent), Chemistry

High School Diploma With Honors, Chemistry