Dmitrii Shcherbinin, Ph.D Email & Phone Number
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Dmitrii Shcherbinin, Ph.D is listed as Bioinformatician | Expert in Molecular Modeling | Experienced Lecturer and Educational Course Creator at AstraZeneca, a with 78605 employees, based in Gothenburg, Västra Götaland County, Sweden. AeroLeads shows a matched LinkedIn profile for Dmitrii Shcherbinin, Ph.D.
Dmitrii Shcherbinin, Ph.D previously worked as Senior Research Scientist at Pirogov Russian National Research Medical University, Institute Of Translational Medicine and Research Scientist at Institute Of Biomedical Chemistry. Dmitrii Shcherbinin, Ph.D holds Doctor Of Philosophy (Ph.D.), Bioengineering And Bioinformatics from Lomonosov Moscow State University (Msu).
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About Dmitrii Shcherbinin, Ph.D
I'm a seasoned Bioinformatician, passionate about exploring the intricacies of molecular structures, drug discovery, and life sciences in general. My career has been centered around academic and contract scientific research, as well as teaching.As a professional researcher, I specialize in a wide range of Structural Bioinformatics approaches such as Molecular Modeling, Molecular Dynamics, and Molecular Docking, along with experience in NGS and RNAseq analysis. My teaching roles, from instructing University courses for bachelor and master students to developing comprehensive educational programs, underline my dedication to knowledge-sharing and inspiring future scientists.My diverse experiences across academic and commercial projects, and the challenges encountered therein, have honed my soft skills in project management, planning, customer communication, collaborative leadership, and problem-solving, furthering my ability to translate scientific insights into practical applications.My goal is to keep contributing to the life sciences sector, utilizing my in-depth research and teaching experience, combined with my skills in management and customer relations. I'm driven by a passion for merging scientific methods with practical know-how, aiming to drive innovation and understanding in areas like drug discovery, biotechnology, medicine, and education
Dmitrii Shcherbinin, Ph.D's current company
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Dmitrii Shcherbinin, Ph.D work experience
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Senior Research Scientist
+ Engaged in advanced research exploring specificity and affinity of interactions within T-cell receptor (TCR) and major histocompatibility complex-peptide (pMHC) complexes.+ Modeled more than 1500 TCR-pMHC complexes structures,elucidated the physical and structural aspects of TCR dimerization and peptide recognition, including the assembly of triple TCR-pMHC complexes and the influence of CDR3 loop variability.+ Analyzed contacting amino acid properties using machine learning techniquesSkills and approaches: Molecular modeling (Rosetta, TCRmodel), scripting (Rosetta, pipelines for high-throughput molecular modeling), statistical analysis of contacting residues properties (R, RF, RFE)
Research Scientist
+ Devised a novel in silico aptamer construction approach targeting thrombin and Cytochrome P450 51A1 proteins, yielding several aptamers with verified affinity and selectivity, backed by experimental correlation with predicted binding energy.+ Explored the impact of single amino acid mutations on thermostability and drug resistance of beta-lactamases, identifying key structural pathways influencing enzyme stabilization.+ Mapped the antibody-ganglioside interactions through molecular modelling, advancing understanding of Fab fragments of antibodies and gangliosides interaction dynamics.Skills and approaches : Molecular dynamics (Amber, Gromacs), molecular docking (Dock6, Autodock, Vina, CABS-dock), binding energy calculation (MM-PBSA), building and analysis of residue interaction networks (RING, Cytoscape), parametrization of molecules, quantum mechanics calculations, scripting
System Administrator
Associate Professor
Developed and have been instructing a comprehensive semester program on'Introduction to Bioinformatics' and 'Basics of Molecular Biology'
Ceo
+ Successfully conducted an in-depth analysis of ligand-protein interactions as a part of adrug discovery project+ Constructed affine peptides for receptor molecules within the framework of a drug discovery project + Performed molecular modeling for the creation of accurate and detailed scientific illustrations
Research Scientist
+ Led comprehensive analysis of gene expression profiles in hematopoietic stem cells+ Conducted statistical analysis in R, ANOVA analysis, analysis of RNAseq data using DESeq, PCA analysis, enrichment analysis, gene network analysis.Skills and approaches : Statistical analysis in R, normalization, ANOVA analysis, analysis of RNAseq data using DESeq, PCA analysis, enrichment analysis, gene network analysis
Expert In Life Sciences
Colleagues at AstraZeneca
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Anita Rayborn, Mba, Ms
Colleague at AstrazenecaDetroit Metropolitan Area, United States
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Işıl Bor
Colleague at AstrazenecaLondon, England, United Kingdom
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Oliver Freeman
Colleague at AstrazenecaStockport, England, United Kingdom
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Vasileios Antonopoulos
Colleague at AstrazenecaGreece
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Karin Diem
Colleague at AstrazenecaAustria
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MP
Miriam Perez Rodarte
Colleague at AstrazenecaMexico City, Mexico
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Heba T.
Colleague at AstrazenecaJeddah, Makkah, Saudi Arabia
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MJ
Manas Jena
Colleague at AstrazenecaCuttack, Odisha, India
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Shubho Chakraborty
Colleague at AstrazenecaKolkata, West Bengal, India
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Christin Bauer
Colleague at AstrazenecaGreat Abington, England, United Kingdom
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Dmitrii Shcherbinin, Ph.D education
Frequently asked questions about Dmitrii Shcherbinin, Ph.D
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What company does Dmitrii Shcherbinin, Ph.D work for?
Dmitrii Shcherbinin, Ph.D works for AstraZeneca.
What is Dmitrii Shcherbinin, Ph.D's role at AstraZeneca?
Dmitrii Shcherbinin, Ph.D is listed as Bioinformatician | Expert in Molecular Modeling | Experienced Lecturer and Educational Course Creator at AstraZeneca.
Where is Dmitrii Shcherbinin, Ph.D based?
Dmitrii Shcherbinin, Ph.D is based in Gothenburg, Västra Götaland County, Sweden while working with AstraZeneca.
What companies has Dmitrii Shcherbinin, Ph.D worked for?
Dmitrii Shcherbinin, Ph.D has worked for Astrazeneca, Pirogov Russian National Research Medical University, Institute Of Translational Medicine, Institute Of Biomedical Chemistry, Moscow Polytechnic University, and Itbiotech.
Who are Dmitrii Shcherbinin, Ph.D's colleagues at AstraZeneca?
Dmitrii Shcherbinin, Ph.D's colleagues at AstraZeneca include Anita Rayborn, Mba, Ms, Işıl Bor, Oliver Freeman, Vasileios Antonopoulos, and Karin Diem.
How can I contact Dmitrii Shcherbinin, Ph.D?
You can use AeroLeads to view verified contact signals for Dmitrii Shcherbinin, Ph.D at AstraZeneca, including work email, phone, and LinkedIn data when available.
What schools did Dmitrii Shcherbinin, Ph.D attend?
Dmitrii Shcherbinin, Ph.D holds Doctor Of Philosophy (Ph.D.), Bioengineering And Bioinformatics from Lomonosov Moscow State University (Msu).
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