Emil Joseph, Ph.D. Email & Phone Number

Houston, Tx, Us

Indianapolis, Us

Formulation development, manufacturing, scale up and technology transfer of nanaoparticulate systems and other diverse/complex formulations for the delivery of Small molecules/Macromolecules/Nucleic acids/Peptides/Proteins for various therapeutic areas using numerous technologies such as microfluidics, homogenization/sonication Participate in development of research strategies and troubleshooting for delivery of Small molecules/Macromolecules/Nucleic acids/Peptides/ProteinsLeading oral dosage form development- tablets (conventional, sustained release, enteric coated, mini tablets), capsules (gelatin, enteric), liquid orals (solutions, emulsions)Compendial dissolution testing development and execution with USP apparatus (Type II, Type III) Polymer synthesis and scale up with optimization of reaction rate, reaction control, heat removal and mixingMethod development, validation and analytical testing of developed/manufactured formulations using techniques such as DLS, HPLC, UPLC, GC, UV, GPC, LC MS, and cell based assaysWrite/review/approve reports, protocols, SOPsAnalyze data from tests and present results to internal team and partnersSupervises technical staff along with work assignment and performance evaluation Train junior level staff and guide the work on development teamPlan, design, and execute protocols; record, interpret and report results for complex studiesAdvance the quality system of company and lead development of testing procedures and creation of SOPsEnsure lab documentation that conforms with company quality systems and partner expectations

⬥ Lead technical team for formulation development, analytical methods and assay development of pharmaceutical, nutraceutical, biological and extended release formulations ⬥ Identifying/developing new technologies to accelerate the biopharmaceutical development process for ongoing projects of company ⬥ Highly involved in decision making, market search, formulating strategies and business development of company

⬥ Formulation development, analytical methods and assay development of biological, neutraceutical and pharmaceutical products⬥ Drug product development based on Si RNA, peptide/protein and biological molecules ⬥ Coined the idea and lead the team which developed and optimized Multivitamin gummy bears with brand name Yummy Grow™ using locally available ingredients (currently in process of commercialization)⬥ Key personnel in commercializing pharmaceutical products for the company like Calvitadent™ (Calcium -Vitamin D formulation), Chlordent Fresh™ (Chlorhexedine IP mouthwash with mint flavour) etc⬥ Managed the team which developed and optimized novel nanoformulation for CNS disease⬥ Key personnel in obtaining official Start up India and Kerala State start up mission approval for the company

Omaha, Nebraska, Us

⬥ Worked closely with CEO on formulation, analysis, process development and scale up of biopharmaceutical product for treating spinal cord injury ⬥ Scaled up nanomedicine in cGMP facility⬥ Written manufacturing and quality control documents as per FDA specifications⬥ Worked closely with Protransit product developmental team to identify and eliminate any sources of variability that can cause lot failures⬥Developed and validated HPLC based analytical methods⬥Performed cell culture studies and kit based assays

Jhunjhunu, Rajasthan, In

Analytical and bioanalytical method development, Preformulation studies, Process optimization, Process scale-up, Stability studies as per US FDA and ICH guidelines, Process validation and technology transfer, Pharmacokinetic and biodistribution studies, In vivo efficacy studies in animal models, Quality by Design (QbD)/Design of Experiments (DoE) based formulation development (Immediate release, modified/sustained release, Novel drug delivery systems), Targeted drug delivery systems

Generic formulation development (IR and CR oral dosage forms, i.v formulations of cephalosporins) for regulated markets

Worked on nanoparticulate systems for cancer chemotherapy and designed formulations for cell culture studies (developed and optimized dextran nanoparticles using emulsification-ultrasonication technique for anti-cancer drug and tested in MCF-7 cell lines).

Doctor Of Philosophy (Ph.D.), Pharmaceutics: Drug Delivery, Pharmacokinetics And In Vivo Study

M.Pharm, Pharmaceutics

B.Pharm, Pharmacy

Pre Degree, 1St Group (Science)

Secondary School Leaving Certificate