Dr. Mandy Bachmann Email & Phone Number

Dresden, Sn, De

Dresden, Sachsen, Deutschland

Dresden, Sachsen, Deutschland

Dresden, Sachsen, Deutschland

Dresden, Sachsen

anvajo GmbH is a technology company that develops, manufactures, and sells innovative solutions for the analysis of liquids. Our compact universal platform for fluid analysis "fluidlab" is based on progressive technologies such as holographic microscopy, machine-learning-supported image analysis, mobile embedded hardware, function-integrated optics and meso- and microfluidic sample carriers.In the bioanalytics team we are responsible for the performance of several R&D projects e.g., urine sediment analysis, spectroscopy, label-free cell counting, blood cell analysis, assay development of blood and urine assays as well as validation and release testing. In addition, we are involved in the image data management for training of our CNN based machine learning models.

Dresden Area, Germany

In my position as Method Development and Genome Engineering Specialist in the Genome Engineering Facility at the MPI-CBG, I was focussing on:- Analysis of different Cas9 protein variants to increase HDR events- Analysis of off-target integration frequency of protein trap cassettes - Reverse genetics in mammalian cells using CRISPR/Cas9 mediated HDR - Development of a genome editing pipeline for protein tagging and gene knockouts in human cell lines using CRISPR/Cas9

Magdeburg, Germany

Characterization of influenza virus replication for the optimization of mammalian cell culture-based influenza vaccine production.

Melbourne, Australia

Development of rapid point of care test systems• proof of principle for a new test system• determination of suitable antibodies • stability and optimization tests • ELISA, lateral flow immunochromatography• cloning and protein expression in mammalian cells• test of clinical samples (PC2)

Dresden, Germany

Analysis of OXPHOS gene expression and mitochondrial biogenesis during differentiation of human mesenchymal stem cells.• gene expression analysis• protein expression analysis• tissue culture and stem cell differentiation

Dresden, Germany

Quantification of ATP/ADP and NADH/NAD+ - levels during human mesenchymal stem cell differentiation. • HPLC analysis to quantify ATP/AXP and NADH/NAD levels• Luminescence based assays to determine ATP concentrationsCloning of different bacterial and yeast protein expression constructs.• DNA work• protein work

Liverpool, United Kingdom

Epidemiological studies of Norovirus infections in children from Ethiopia and Yemen.• virus extraction and RNA isolation• realtime PCR• ELISA• data collection and analysis