Dr. Michele Schaefer Email & Phone Number

Elkridge, Md, Us

Elkridge, Md, Us

Venlo, Limburg, Nl

Support QuantiFERON and QIAreach portfoliosIntellectual property support and defenseInnovation New product developmentLine management

Venlo, Limburg, Nl

Baltimore, Md, Us

Examined the effect of disrupting PDZ interactions to unravel early anesthetic exposure-produced cognitive dysfunction. Utilizing biochemistry, behavior, physiology, cellular and molecular biology this project evaluated the long-term impact of inhaled anesthetics on cognition and the role of disrupting synaptic PDZ interactions in the developing brain.Co-wrote NIGM RO1 and assisted PI in overseeing progress and reports.Trained students and staff on neuroscience team

Laurel, Maryland, Us

Examined inflammation in blast-induced neurotrauma using novel imaging methods, molecular biology, behavior, physiology, and pathology.Managed US ARMY DoD grant “The Importance of Neurogenic Inflammation in Blast-Induced Neurotrauma”Managed subcontractors, trained students, and staff.Immunology: Development and optimization of approaches for rapid vaccinationForensic: Development and optimization of methods for resolving complex DNA mixturesCommunity: Volunteer reviewer of engineering projects. Volunteer on the Institutional Biosafety Committee. Mentor to dozens of high school interns

Laurel, Maryland, Us

Examined inflammation in blast-induced neurotrauma using novel imaging methods, molecular biology, behavior, physiology, and pathology. Trained students and staff.

Bethesda, Md, Us

Developed and studied an in vivo mouse olfactory model of traumatic brain injury and repairPerformed penetrating traumatic brain injury and measured cellular, molecular, and behavioral changes

Baltimore, Md, Us

Generated a MUP4 null mutant (KO) mouse and applied molecular, physiological, and behavioral approaches to understand the role of this nasal major urinary proteins in olfactory sensitivityCo-wrote R21 proposal which was funded and all deliverables were met.

Baltimore, Md, Us

Utilized both established and novel chemical analytical tools to detect MHC-determined chemosignals in mouse samplesCo-wrote Defense Advanced Research Projects Agency (DARPA) technical proposal which was funded and all deliverables met.

Denver, Co, Us

Generated an expression library of olfactory receptors responsive to urine odorFunctionally expressed olfactory receptors using adenoviral system in mice and cellsInvestigated functional olfactory receptor response using calcium imaging, fluorescence, and electrophysiologyPost-genomic Fellowship Award 2001Invited speaker at The Wellcome Trust Sanger Institute Annual Meeting, England 2001

Denver, Co, Us

Investigated neural mechanisms of olfactory discrimination of odortypes in mice Acquired and analyzed complex spatial neuronal activity patterns in the olfactory bulb in response to odortypes (e.g. MHC) expressed in urineDefined the variability of position of a neural processing unit (i.e. glomerulus) within the olfactory bulbAwarded Pre-Doctoral National Research Service Award, National Institutes of HealthDon Tucker Award for Best Presentation, AChemS Annual Meeting 2000

Generated an adenylyl cyclase type 8 null mutant mouseDeveloped in situ hybridization techniques and rapid PCR screens, phage cloning, animal surgery, ELISAs, radioimmunoassays, animal colony maintenance, and genotyping

Performed extensive analytical PCR assays (e.g. for imprinting, methylation, and/or polymorphisms) in a variety of studies on cancers and precancers

B.A./M.A., Biology/Biotechnology

Ph.D., Neuroscience