Roy Lester Email & Phone Number

Milton Hill, England, United Kingdom

Milton Hill, Abingdon

Milton Hill, Abingdon

Working as a lead organic chemist in a new department within compound delivery, lube science. Synthesising oil additives while paying close attention to the safety and hazards of each reaction.

Welwyn Garden City, Hertfordshire, United Kingdom

• Key role in the successful design, generation and development of lead compounds which were acquired by a major US biotech for clinical development.• Significant contribution towards designing a highly efficient antibiotic drug candidate by understanding and utilising SAR of activity, LogP, tissue distribution and toxicity.• Interacted with a multidisciplinary team, that ensured clear communication, contributing to the forward development of the project.• Assisted with microbiological evaluation of data sets which helped maintain a constant flow of data used to profile compounds • Used resourceful and innovative methods to maintain equipment without funding for expensive repairs, which ensured deliveries and milestones were achieved.• Synthesis of small molecules to large cyclic peptide antibiotics (1500-2500 Da) incorporating a number of synthetic strategies including scale-up of selected targets.• Self-taught to become lead user for the preparative HPLC while encompassing the development of purification methodology to separate difficult diastereoisomers.• Deduced that calculated properties were not adequate with our targets and established a practical method with analytical HPLC to understand the physical properties better. • The analytical HPLC method led to the discovery of a yet unidentified impurity.

Milton Park, Didcot

• Synthesised a number of multistep drug targets with a quinazoline core.• Developed 4 methodologies for the fast and efficient synthesis of a drug target core.• Supervisory responsibility of junior colleague.• Contributed to designing and running synthetic strategy workshops.• Solely implemented a compound database and storage for over 500 compounds.• Designed a method to form a library of compounds in an efficient manner to QC standards.

Nottingham, United Kingdom

• Completed a number of methodology projects, based on catalytic nitrile activation and heterocycle formation.• Mentoring of 6 masters/summer students.• Contributed to the efficient running of the laboratory.

Stevenage, United Kingdom

I worked in the department of isotope labeling, in which I learnt a great deal about working in industry and synthetic practice. this included working with hazardous materials and expensive labeled reagents. During my time I devised and executed a novel synthetic route and accomplished the synthesis of 3 multistep drug compounds.

Doctor Of Philosophy - Phd, Organic Chemistry

Within my graduate research I developed a number of novel organic synthetic methodologies centered around catalytic nitrile activation..

Masters In Chemistry, Synthesis Of Compostable Plastic From Starch And Deep Eutectic Solvents

Worked under Prof. Andrew Abbot for my fourth year project. this included displaying and explaining the work to ages ranging from 5-70.

Gcse And A Levels