Dr. Sandip Gavade Email and Phone Number

• Three Patents filed for novel potential Anticancerous molecule, with particular emphasis on cancer stem cell (CSC) inhibitor development for preventing cancer relapse.• Two novel molecules identified through in-vitro screening have entered preclinical trials.• Received U.S Patent grants for novel anticancer molecule which has received IND approval by INDIAN FDA for phase I clinical trials.• One Anticancer molecule in in preclinical development of one potential anti-CSC lead molecule.• Drug discovery: Initiate project for Anticancer activity, Design molecules for Anti-cancer activity with novelty search.• Synthesis of maximum number of NCE’s for Anti-Cancer project.• Optimization of synthetic route for active compounds to improve yield and purity.• Purification and characterization of compounds by different spectroscopic methods.• Process development for specialty chemicals

• Synthesis of compounds in flow chemistry using flow equipment like vapour tech, Syrris pump, Syrris reactor, H-Cube, Phoenix reactor, Chemix pump, Hallmark pump etc. In flow chemistry handled reagents like n-BuLi, Grignard, Pd/C, Raney Ni, Jones reagent etc. Handled reactions like Homogenous reaction, Heterogeneous reaction, Jones oxidation, Reduction, Suzuki, Sonogashira, Grignard, Bromination, Nitration, Aldol condensation etc.• Synthesis of polymer, • Synthesis of Amplifier fluorescence polymer.• Synthesis of compounds for explosive detection.

Process development, reduce cost of product using selection of proper route, leading group

Lead group, assign work, deliver compounds in require time

Synthesis of organic compounds, design molecule for therapeutic area, Optimization and selection of synthetic route

Synthesis of organic Compounds