Dr. Simone Thair

Dr. Simone Thair Email and Phone Number

Senior Data Scientist @ Stanford University
Stanford, CA, US
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Stanford, California, United States, United States
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About Dr. Simone Thair

Selected PublicationsThair S*, He Y*, et. al. Transcriptomic similarities and differences in host response between SARS-CoV-2 and other viral infections. iScience Epub [ahead of print] 2020 Dec 14. iScience 24, 101947, January 22, 2021*co-first authorRam-Mohan N., Thair S, et. al. Integrative profiling of early host chromatin accessibility responses in human neutrophils with sensitive pathogen detection. bioRxiv 2020.04.28.066829; doi: https://doi.org/10.1101/2020.04.28.066829Blauwkamp TA*, Thair S*, et. al. Analytical and clinical validation of a microbial cell-free DNA sequencing test for infectious disease. Nat Microbiol. 2019 Apr;4(4):663-674. Epub 2019 Feb 11. PMID: 30742071.*co-first authorThair SA, et al. Tumor Necrosis Factor Alpha Induced Protein 2 (TNFAIP2) Inhibits Early TNFa induced NF-kB Signaling and Decreases Survival in Septic Shock Patients. Epub ahead of print 9Sept2015. J Innate Immun Thair S, Russell JA. Noncanonical Nuclear Factor Kappa B (NF-κB) Signaling and Potential for Therapeutics in Sepsis. Curr Infect Dis Rep. 2013 Oct;15(5):364-71.Thair SA and Russell JA. Sepsis in transit: from clinical to molecular classification. Crit Care. 2012 Nov 14; 16(6):173Thair SA, Walley KR, Nakada TA, McConechy M, Boyd JH, Wellman H, Russell JA. A Single Nucleotide Polymorphism in NF-κB Inducing Kinase is Associated with Mortality in Septic Shock. J Immunol. 2010 Feb 15; 186(4):2321-8. Walley KR, Thain KR, Russell JA, Reilly MP, Meyer NJ, Ferguson JF, Christie JD, Nakada TA, Fjell CD, Thair SA, Cirstea MS, Boyd JH. PCSK9 is a critical regulator of the innate immune response and septic shock outcome. Science Transl Med. 2014 Oct 15;6(258):258Fjell C, Hsu JL, Boyd J, Thair S, Walley KR, Russell J. Cytokines and signaling molecules predict clinical outcomes in sepsis. PLoS ONE. 2013 Nov 14;8(11)Russell JA, Fjell C, Hsu JL, Lee T, Boyd J, Thair S, Singer J, Patterson AJ, Walley KR. Vasopressin compared with norepinephrine augments the decline of plasma cytokine levels in septic shock. Am J Respir Crit Care Med. 2013 Aug 1;188(3):356-64. Nakada TA, Russell JA, Boyd JH, McLaughlin L, Nakada E, Thair SA, Hirasawa H, Oda S, Walley KR. Association of Angiotensin II Type 1 Receptor-Associated Protein Gene Polymorphism with Increased Mortality in Septic Shock. Crit Care Med. 2011 Jul; 39(7):1641-8ALL PUBS: http://www.ncbi.nlm.nih.gov/pubmed/?term=simone+thairALL PREPRINTS: search medRxiv and/ or bioRxiv + Simone Thair

Dr. Simone Thair's Current Company Details
Stanford University

Stanford University

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Senior Data Scientist
Stanford, CA, US
Dr. Simone Thair Work Experience Details
  • Stanford University
    Senior Data Scientist
    Stanford University
    Stanford, Ca, Us
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  • Stanford University
    Senior Data Scientist
    Stanford University Sep 2022 - Present
    Stanford, California, United States
    Senior Data Scientist Khatri Lab
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  • Harvard University
    Affiliate Research Fellow
    Harvard University Mar 2019 - Present
    Boston Children'S Hospital
    Bioinformatics of Pediatric Critical Illness in Severe Influenza
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  • Freelance
    Senior Computational Biologist
    Freelance Feb 2022 - Oct 2022
  • Inflammatix, Inc.
    Senior Computational Biologist
    Inflammatix, Inc. Oct 2019 - Feb 2022
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  • Stanford University
    Postdoctoral Fellow
    Stanford University Nov 2014 - Oct 2019
    Stanford, Ca
    To investigate transcriptomic and epigenetic profiling of critical illnesses for potential biomarker discovery in order to develop assays for disease diagnosis and prognosis, as well as screen for targeted therapies and understand their mechanisms of action using analytical and clinical studies
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  • The University Of British Columbia
    Ubc Medicine Pbl/ Cbl (Problem Based Or Case Based Learning) Tutor
    The University Of British Columbia Jan 2014 - Nov 2014
    Responsible for understanding medical physiology/ pathology/ etiology and specifics of weekly patient cases in order to guide UBC medical students in a problem based learning course design through the patient case(s) and ensure all medical case based learning objects are covered.
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  • Clinical Chemistry St. Paul'S Hospital
    Clinical Researcher
    Clinical Chemistry St. Paul'S Hospital Jun 2014 - Oct 2014
    Vancouver, Bc
    Developing a novel method for rapid detection of urinary tract infections with mass spectrometry that will eliminate the need for culturing bacteria.
  • Infinity Cohort Systems
    Owner/ Consultant
    Infinity Cohort Systems Jan 2012 - Oct 2014
    Vancouver, Canada
    Consultant/ Owner Infinity Cohort Systems. Vancouver, B.C. I have developed a system for biobanking clinical samples for academic cohorts. I customize &implement the system of equipment, documents & SOPs, train the staff, provide support, provide basic data audits & analysis of subsequent results.
  • St. Paul'S Hospital Intensive Care Unit
    Clincial Trial And Academic Study Research Co-Ordinator
    St. Paul'S Hospital Intensive Care Unit Sep 2013 - Jul 2014
    Vancouver, Canada Area
    Clinical Skills• Attend rounds, read and asses ICU patient charts• Determine inclusion and/ or exclusion for clinical trials.• Obtain informed consent. • Information resource for enrolled patients and/ or family.• Perform all study related procedures including ECGs.• Collect data for case report forms.
  • University Of British Columbia
    Phd, Experimental Medicine
    University Of British Columbia Sep 2008 - Sep 2013
    Department Of Medicine
    My project looked at the influence of polymorphisms of key genes in the NF-kB signaling pathway and how they influence mortality in septic shock.Thair SA. (2013) The Discovery of Functional Single Nucleotide Polymorphisms and Novel Gene Mechanisms that May Explain Mortality and Organ Dysfunction in Septic Shock Patients. (Doctoral Dissertation). https://circle.ubc.ca/
  • Ubc James Hogg Research Centre
    Lab Manager For Dr. Keith Walley
    Ubc James Hogg Research Centre Sep 2008 - Aug 2013
    Vancouver, Canada
    Technical Skills• Survival Analysis Statistics• Statistical Analysis of Clinical Phenotypic and Genotypic Data (Basic)• Basic Bioinformatics• Tissue Culture• DNA/ RNA/ protein extraction and purification• PCR, qPCR, allele specific expression (ASE), genotyping• Cloning and site directed mutagenesis (SDM)• Transfection and assay of cloned constructs • EMSA, Western, Southern and Northern Blot.• Co-immunoprecipitation and interpretation of mass spectrometry results• ELISALab/ Project Management Skills• Hiring and training of co-op students and technicians.• Mentoring and supervision of co-op students. • Training post-doctoral and clinical fellows as needed. • Project management, anticipation of needs, technical support, experimental design, reagent and equipment ordering, data analysis and preparation for publication. • Point person for national collaborations including co-ordination of preparing samples en mass for shipment for collaborations and management of subsequent return of data. • Data quality control and aligning phenotypic and genotypic data for patients. Clinical Cohort Management SkillsSPHICU Genetics of SIRS and VASST (4 cohorts total > 4000 patients)Molecular Signature of Sepsis (1 cohort > 250 patients)• Organize and bank blood and plasma samples. • Organize and maintain all consent documentation and files for randomization of patient information. • Liaise with/ organize blood samples received from co-operating hospitals • Hire and train university co-op students to assist with the organizing and banking portion of this project and supervise their work.
  • Ubc James Hogg Research Centre
    T3 Technician
    Ubc James Hogg Research Centre Jan 2007 - Aug 2008
    Vancouver, Canada

Dr. Simone Thair Skills

R Clinical Research Biotechnology Molecular Biology Project Management Project Planning Lifesciences Western Blotting Cell Biology Genetics Biochemistry Cell Culture Scientific Writing Pcr Elisa Qpcr Bioinformatics Protein Chemistry Dna Life Sciences

Dr. Simone Thair Education Details

Frequently Asked Questions about Dr. Simone Thair

What company does Dr. Simone Thair work for?

Dr. Simone Thair works for Stanford University

What is Dr. Simone Thair's role at the current company?

Dr. Simone Thair's current role is Senior Data Scientist.

What is Dr. Simone Thair's email address?

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What is Dr. Simone Thair's direct phone number?

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What schools did Dr. Simone Thair attend?

Dr. Simone Thair attended Stanford University, The University Of British Columbia, Britsh Columbia Institute Of Technology, The University Of British Columbia.

What are some of Dr. Simone Thair's interests?

Dr. Simone Thair has interest in Social Services, Environment, Health.

What skills is Dr. Simone Thair known for?

Dr. Simone Thair has skills like R, Clinical Research, Biotechnology, Molecular Biology, Project Management, Project Planning, Lifesciences, Western Blotting, Cell Biology, Genetics, Biochemistry, Cell Culture.

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