Daniel Speidel Email and Phone Number
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I am a senior management executive and biomedical scientist with 20 years experience in life sciences. Currently, I am Managing Director of Breakpoint Therapeutics GmbH, a VC-funded spin-off company of Evotec that I co-founded. Breakpoint is dedicated to the discovery and development of anti-cancer drugs that target the DNA Damage Response in cancer cells. At Breakpoint, I'm responsible for all corporate matters and operations.Before joining Breakpoint Therapeutics I worked at Evotec with the main aim to facilitate formation of a spin-off company in the area of DNA Damage Responses. This spin-off company is Breakpoint Therapeutics.Prior to Evotec I was an academic researcher, senior lecturer and research group leader in Germany and Australia. My research interests have focused on (1) understanding cellular DNA damage responses at the molecular and genetic level, (2) the discovery of molecular drug targets and new medicines, and (3) the identification and validation of new biomarkers that can predict the success of cancer therapy. A former management consultant with McKinsey & Company, I have also advised several research-related organisations and other institutions on matters of strategic importance and helped my clients grow, change and further develop their unique, individual strengths.I have served on many high-profile boards and committees, including research institute governing boards, grant review and selection panels, conference organising committees, editorial boards of international scientific journals, and the advisory boards of research and music organisations.Advisory, governing & editorial board memberships have included: - Cure Cancer Australia Foundation - Tour de Cure Australia - Cancer Australia - ResearchGATE - German Scholars Organization - Frontiers in Oncology - Mammalian Genome - Heinrich-Pette-Institute - Landesmusikrat Niedersachsen
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Managing DirectorBreakpoint Therapeutics Gmbh Jul 2019 - PresentHamburg, Hh, DeBreakpoint Therapeutics is a spin-off of Evotec SE dedicated to the discovery of anti-cancer drugs that target the DNA Damage Response (#DDR) in cancer cells. The new company will advance drug discovery programs initiated internally at Evotec and develop first-in-class oncology drugs that interfere with DNA-repair and replication stress tolerance pathways. Our aim is to develop drugs that succeed and complement PARP-inhibitors and facilitate the cure of therapy-resistant cancers.Breakpoint Therapeutics is backed by a consortium of renowned life science investors: Medicxi, Taiho Ventures, Evotec and BVF Partners.www.breakpointtx.com -
Independent Management Consultant And Advisor-- 2000 - PresentI have advised a number of organisations, mainly in the medicine/biotech/research and not-for-profit sectors, and helped with specific tasks. My former clients include also two market-leading global players. Topics have included strategy, business development, growth/merger/acquisitions, recruiting and event management.
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Vice President, Initiative Leader OncologyEvotec May 2018 - Jun 2019Hamburg, DeMy main task was to establish an Evotec Innovate project as a virtual spin out company. This included development and implementation of a commercial and scientific strategy. In addition, I established partnerships with co-investors/VCs and academic experts to help us succeed. In June 2019, these activities led to formation of Breakpoint Therapeutics GmbH - the spin-off company of Evotec that I was entrusted to lead as Managing Director. -
Conjoint Senior LecturerUniversity Of Sydney Feb 2011 - Jun 2018The University Of Sydney, New South Wales, Au- Supervision of postgraduate research students -
Senior Research Scientist/ Group LeaderChildren'S Medical Research Institute Jun 2007 - May 2018Westmead, Nsw, AuExperimental cancer research.My research explored how normal and cancer cells respond to radiation and chemotherapeutic agents. The overall aims were to understand better the molecular basis of tumour suppression and improve cancer therapy. My activities included:- Management and supervision of independent cancer research program and team - Budget responsibility - Dissemination of results through peer reviewed publications and presentations at international conferences and invited seminars- Acquisition of funding through grant applications in competitive funding schemes- Collaboration with leading clinical oncologists - Expert assessment and evaluation of scientific research proposals (grants & fellowship applications) and manuscripts for leading international research organisations/ journals- Co-organisation of national cancer research conferences- Editor of international cancer research journals- Mentor of students, postdoctoral fellows and junior research staffTopics: cancer, therapy response, personalised medicine, DNA damage responses, p53, mechanisms of tumour suppression and therapy response, biomarkers predicting cancer therapy resistance, radiation biology -
Postdoctoral Research FellowHeinrich Pette Institute For Experimental Virology And Immunology At The University Of Hamburg Aug 2004 - Jun 2007Hamburg, DeExperimental cancer research in the laboratories of Prof. Dr. Wolfgang Deppert (Dept. of Tumor Virology) and Dr. Carol Stocking (Molecular Pathology Group). My research elucidated the function of the tumour suppressor gene p53 and identified the Gadd45beta gene as a novel regulator associated with therapy resistance in blood cancer. -
Doctoral StudentHeinrich-Pette-Institut 2000 - 2004Hamburg, DeExperimental cancer research in the laboratory of Professor Wolfgang Deppert (Dept. of Tumor Virology).My research focused on the tumour suppressor protein p53 and the question as to how p53 promotes cell death or survival of cells that were treated with DNA damaging agents.My publication in the journal Oncogene, describing the results of my PhD thesis, was awarded the renowned Konjetzny Award for Cancer Research. -
ConsultantMckinsey & Company 2000 - 2001UsI analysed the recruitment and selection processes for new hires at McKinsey and recommended substantial changes. All of my major recommendations have been implemented and changed the strategy by which the German Office of McKinsey recruits new consultants - up to now. -
ConsultantMice & More 2000 - 2000I advised the managing partners of this newly founded biotech start-up on matters of strategic relevance. In particular, I evaluated the strategic fit and benefits of a plan to establish a new oncological business unit and thereby expand the company. Following my recommendation, the management of Mice & More decided to not pursue this expansion.
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Consultant/Summer FellowMckinsey & Company 1999 - 1999UsStrategic business consulting.I worked on a growth study for a client in the processing industry and helped to prepare a successful acquisition.
Daniel Speidel Skills
Daniel Speidel Education Details
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Leibniz Universität HannoverCancer Research -
Leibniz Universität HannoverBiochemistry -
Leibniz Kolleg TübingenStudium Generale
Frequently Asked Questions about Daniel Speidel
What company does Daniel Speidel work for?
Daniel Speidel works for Breakpoint Therapeutics Gmbh
What is Daniel Speidel's role at the current company?
Daniel Speidel's current role is Managing Director & Co-Founder at Breakpoint Therapeutics GmbH.
What is Daniel Speidel's email address?
Daniel Speidel's email address is da****@****.edu.au
What schools did Daniel Speidel attend?
Daniel Speidel attended Leibniz Universität Hannover, Leibniz Universität Hannover, Leibniz Kolleg Tübingen.
What are some of Daniel Speidel's interests?
Daniel Speidel has interest in Science And Technology, Social Services.
What skills is Daniel Speidel known for?
Daniel Speidel has skills like Cancer Research, Cell Biology, Cell, Cell Culture, Apoptosis, Laboratory, Cancer, Molecular Biology, Dna, Western Blotting, Life Sciences, Cell Cycle Analysis.
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