Drew Tack Email & Phone Number

Seattle, Wa, Us

Seattle, Washington, United States

Vancouver, Washington, United States

Led a project to address significant challenges hindering the clinical potential of a protein therapeutic. Designed and coordinated the execution of our strategic workplan; set goals, establish timelines, and assess risk, communicate results and status. risks. Regularly engaged with stakeholders to ensure project was meeting scientific and business goals. Spearheaded a strain engineering initiative to improve productivity of a microbial strain. Employed a data-driven strategy within a… Show more Led a project to address significant challenges hindering the clinical potential of a protein therapeutic. Designed and coordinated the execution of our strategic workplan; set goals, establish timelines, and assess risk, communicate results and status. risks. Regularly engaged with stakeholders to ensure project was meeting scientific and business goals. Spearheaded a strain engineering initiative to improve productivity of a microbial strain. Employed a data-driven strategy within a tight timeframe, developed a plan to strategically modify the host genome and establish a complementary upstream growth process. Increased stain efficiency to greater than 90% and productivity improved up to 300%.Beyond my leadership duties, I remain active in experimental work. In pursuit of a novel enzymatic activity, I've identified a variant from public genome databases which I engineered for increased activity and substrate specificity. Show less

Gaithersburg, Md

As a member of the Cellular Engineering group, I collaborated with a multi-disciplinary team to pioneer groundbreaking methodologies for engineering transcription factors with precisely defined functional parameters. I developed a method implementing a combination of long-read and short-read next-gen sequencing to measure the activity of nearly 10^5 sensors across 24 different growth conditions simultaneously. This effort marked an early demonstration of precision engineering in biology… Show more As a member of the Cellular Engineering group, I collaborated with a multi-disciplinary team to pioneer groundbreaking methodologies for engineering transcription factors with precisely defined functional parameters. I developed a method implementing a combination of long-read and short-read next-gen sequencing to measure the activity of nearly 10^5 sensors across 24 different growth conditions simultaneously. This effort marked an early demonstration of precision engineering in biology, showcasing quantified accuracies of engineering efforts. Additionally, using this approach, we identified several novel phenotypes, some of which had not been described prior to this work, that provided insight into sequence-structure-function relationships underlying these phenotypes.In partnership with a multidisciplinary team, we ensured the data from this work met the quality requirements for machine learning efforts. This approach laid the foundation for the emergence of novel machine learning techniques in protein engineering for genetic sensors, as well as more generalizable understanding of protein landscapes. Show less

Austin, Texas, United States

Ph.D., Biochemistry

Bs, Chemistry