Joseph A. Bauer, Ph.D. Email & Phone Number

Akron, Oh, Us

North Canton, Ohio, Us

As the Founder, President, and Director of Laboratory Services at Nitric Oxide Services, LLC, I have led our company in becoming a full-service resource dedicated to helping companies commercialize their pharmaceutical and medical device products. We offer comprehensive consulting services, study planning for both pre-clinical and clinical phases, FDA submission guidance, and technology transfer solutions. Our client base ranges from Fortune 250 companies to emerging biotech startups.My expertise is in the design and implementation of custom projects that harness nitric oxide delivery systems, evaluating nutraceuticals involved in one carbon metabolism, and helping to commercialize medical devices. These projects consistently exceed client expectations, leading to numerous regulatory and patent filings.Additionally, I oversee the design and execution of comprehensive pharmacokinetic and pharmacodynamic studies conducted with full Institutional Animal Care and Use Committee (IACUC) approvals. My leadership in these critical studies has directly contributed to successful Investigational New Drug (IND) filings, demonstrating our commitment to advancing scientific inquiry and supporting client goals in the biotechnology sector.For more information, please visit http://www.nitricoxidelab.com

Sugar Land, Us

I function as a Senior Editor with cancer drug discovery and development as my area of expertise. Although I edit a wide variety of manuscripts involving biochemistry.http://www.medjaden.com/mbsen/ch/index.aspx

Akron, Ohio, Us

As the Founder and Treasurer of the Bauer Research Foundation, Inc., I represent the organization in civic and professional activities both locally and nationally. I am dedicated to advancing our mission of strengthening the human-animal bond by promoting equitable therapies and medical treatments in comparative medicine, particularly in cancer treatment. Our work benefits both companion animals and their human guardians, ensuring that both receive the best possible care. For more information, please visit https://www.bauerresearch.org/.

As CEO and Director of Translational Medicine & Diagnostics at BNOAT Oncology, Inc., I successfully procured a Small Business Innovation Research (SBIR) contract with the National Cancer Institute (NCI), spearheading advancements in cancer research and drug development. I led the scale manufacture of our lead drug asset, adhering strictly to current Good Manufacturing Practice (cGMP) standards to ensure high-quality production. My leadership extended to the development of a stability-indicating analytical method that accurately assesses the lead drug substance, enhancing our analytical capabilities and ensuring regulatory compliance.In the early stages of drug development for our lead API, an oncology drug, I played a crucial role in identifying, managing, and collaborating with Contract Research Organizations (CROs), Contract Manufacturing Organizations (CMOs), and medical institutions. These partnerships were vital for advancing our research and development efforts, ensuring the efficient and compliant progress of our drug development pipeline.I also identified cancer-specific protein biomarkers and developed quantitative immunohistochemical protocols, which have been instrumental in advancing our diagnostic precision. Leading the pre-Investigational New Drug (pre-IND) application submission, I provided critical Phase I and II FDA guidance, setting the groundwork for successful clinical trials and regulatory approval processes. Through my comprehensive approach and strategic leadership, BNOAT Oncology, Inc. has been well-positioned for success in the competitive landscape of oncology drug development.

Cleveland, Ohio, Us

As an independent researcher at the Taussig Cancer Center, I specialized in drug design and the development of novel drugs with a focus on targeted cancer drug delivery. My responsibilities included supervising lab activities, managing financial accounts and budgets, and increasing public awareness through community outreach and scientific meetings. I secured over $300,000 in project funding from philanthropic sources and designed and oversaw the renovation of a drug synthesis lab capable of producing GLP-quality Active Pharmaceutical Ingredients.I implemented a chemotherapy evaluation model using client-owned animals, based on the National Cancer Institute's Comparative Oncology Clinical Trial Consortium. My research garnered international media attention and was featured in US News and World Report, Forbes, Web MD, MSNBC Health and Medicine, the American Chemical Society, and various local news outlets.Additionally, I helped establish an income-generating resident training program for oncology pharmaceutical sales representatives and served on the Cancer Center’s Research Project Council, responsible for awarding internal research grants. I also participated in Six Sigma training and its implementation to enhance overall quality and improve outcomes for World Class Service and World Class Care initiatives.

Cleveland, Ohio, Us

During my tenure as a Research Associate Staff at the Taussig Cancer Center, I was one of the youngest scientists to be promoted to the professional staff. My areas of specialization included signal transduction pathways and apoptosis, cobalamin chemistry, molecular biology, and the biochemistry of nitric oxide. Collaborating with many leaders in the scientific oncology community, I strengthened the focus and presentation of my research.I actively pursued grant funding and worked with several intra-institutional and national research laboratories. My research was published in high-profile international scientific journals, and I gave numerous presentations tailored to various audiences. Collaborating with mid-size drug development companies, I advanced my work from the bench top to the bedside, gaining familiarity with FDA requirements for obtaining an IND.Notably, I was the only cancer researcher in the USA to be awarded the RAID (2006) from the Developmental Therapeutics Program (DTP) of the NCI.

Cleveland, Ohio, Us

As a postdoctoral fellow in the Immunology Department at the Lerner Research Institute, I honed and practiced a wide array of molecular biology techniques both in vitro and in vivo. These techniques included Western Blot, ribonuclease protection assay (RPA), electrophoretic mobility shift assay (EMSA), flow cytometry, tissue culture, and cell staining.I applied these techniques to my research project, which focused on the role of interferons in T-cell signaling mechanisms, with a particular emphasis on the JAK/STAT signaling pathway. This experience provided me with a solid foundation in molecular immunology and advanced my expertise in cutting-edge research methodologies.