Dror Sever Email & Phone Number

Denmark

Key skills, tasks, and responsibilities:* Data and Information Scientist, working with multiple scientific and clinical databases, text mining platforms, and search engines.* Author of state-of-the-art Literature Search Protocols, Clinical Literature Reviews and Reports for Clinical Evaluation Reports (CER), for the entire Novo Nordisk medical device.

Copenhagen Area, Capital Region, Denmark

• The main aim of my research is to study the cellular and molecular responses of pancreatic progenitor cells at different time points following cellular ablation. During the last two years, I mentored a MD-PhD student.
• Regulation of calcium signaling, cellular maturation and function of β-cells by non-canonical Wnt signaling.
• Using in silico modeling, and whole mount pancreatic sample 3D Image analysis, we demonstrated that the process of pancreatic network development can be deconstructed into two simple rules. An early stage of the.
• The in vivo role of the neuronal transcription factor REST in endocrine differentiation during pancreas development.The main achievements from my training in DanStem are:
• Further developed as an expert within the field of translational diabetes research.
• Involved in successful scientific collaborations.

Copenhagen Area, Capital Region, Denmark

The aim of my research was to study pancreas development and regeneration in-vivo, in order to identify novel regulatory pathways involved in pancreatic progenitor expansion and differentiation. The overall goal of the study was to improve in-vitro pancreas-progenitor differentiation protocol, by activating these pathways. Hard scientific skills: - IHC &.

The Hebrew University, Hadassah Ein Karem Campus

• Cell Physiology course description: Physiology of excitable tissues, nerve, muscle, contractility and synaptic transmission.
• Systems Physiology course description: The physiology of a number of systems in the healthy human body, and specifically emphasizing the integration between them: the cardiovascular, the respiratory, thermoregulation.

Faculty Of Medicine, The Hebrew University, Jerusalem, Israel.

• My Ph.D. research aim was to generate beta-cells exhibiting resistance to autoimmune destruction or with prolonged islet graft survival at various stages of Type 1 diabetes onset. My hypothesis was that inhibiting the.
• The involvement of the cell-surface glycoprotein, and mesenchymal marker CD44 in the autoimmune process, at different time points during the onset of type 1 diabetes.
• Using an pancreatic islet transplantation model, we demonstrated that inhibition of the proinflammatory transcription factor NF-kB, has a protective effect on allogeneic pancreatic islet graft survival.
• Involvement of thioredoxin-interacting protein (TXNIP) in glucocorticoid-mediated beta cell death.

Jerusalem, Israel

Contributed to successfully complete safety and pharmacodynamics phase I of an oral insulin pill.

Jerusalem, Israel

Laboratory Practice in Biochemistry for 2nd year biology students.

Hadassah University Hospital, Ein Karem Jerusalem

Phd Candidate, Biochemistry And Endocrinolgy

Master Of Science (Msc), Medical Scientist And Endocrinology, 94.72

Bachelor Of Medical Science (Ba.Med), Medicine, 90.3

Computer Engineering