Sean O'Brien work email
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Sean O'Brien personal email
Biotech executive with significant success in growing early stage and start-up value through program design and management underpinned by relationship building. A logical and skilled problem-solver who has hands on experience in influencing cross-functional teams to achieve corporate milestones. Key strengths are corporate strategy and management, driving consensus and building, negotiating and successfully managing alliances.Areas of Expertise: •Scientific Program Management • Translational Sciences • Strategy Implementation • Drug Discovery and Development •Business Development • Virtual Pharma • Intellectual Property •Contract Negotiation •Legal Review • CRO and Vendor Management • Scientific Collaborations •Due Diligence
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Co-Founder And CeoSisu PharmaSan Diego, Ca, Us
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Cofounder And CeoSisu Pharma May 2019 - PresentSan Diego, California, UsTargeting Cellular Stress to Treat Cancer and Neurodegenerative Disease
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Founder At Endless Frontier LabsEndless Frontier Labs Sep 2022 - Jun 2023New York, Ny, UsEndless Frontier Labs (EFL) is a New York-based mentorship program supporting promising startups across the globe by helping them grow their business, scale their teams, and advance human welfare through science and technology based-entrepreneurship. Startup founders work with EFL’s network of investors, scientists, and industry experts with support from NYU Stern MBA consultants to maximize the potential for growth. -
Vp Translational SciencesChaperone Therapeutics, Inc. Feb 2019 - Jun 2021Chaperone develops breakthrough therapies for disorders of protein misfolding -
Co-Founder And CeoG4 Oncology Jan 2018 - Dec 2019Small molecule oncology company targeting regulatory DNA motifs
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Co-Founder And Vp, Scientific And Corporate AffairsTrilogy Therapeutics Sep 2015 - Jan 2017Established business opportunity and strategy, business plan and co-founded companyRecruited KOLs to Advisory BoardScientific program review – identified areas required for value creation and established a plan to create complete partnering package post Phase I proof-of-conceptCoordinated compound supply chain to CMODesign and execution of in vivo proof-of-concept studies coordinating multiple CROsNegotiated Material Transfer Agreements, Memorandums of Understanding, Confidential Disclosure Agreements, Consulting Agreements, Master Service Agreements
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Vp, Corporate DevelopmentSenhwa Biosciences May 2013 - Sep 2015San Diego, California, UsIntegral part of team that took two non-clinical compounds with inactive programs into Phase I and Phase II studies, propelling the company to public listing and a $300MM valuation from $35MM investment in 18 monthsSet strategy - conceptualized and designed Phase II cancer study. Oversaw establishment of multicenter US/Korea/Taiwan trial with high caliber institutions in all countriesTook preclinical compound through toxicology studies to IND filing, including FDA interactions, toxicology studies and Clinical Protocol developmentInstigated and delivered $103MM + equity Licensing deal for a preclinical oncology program Negotiated and finalized Clinical Trial Agreements with 8 different institutions in 2014Developed partnerships with academic institutions - $9MM SU2C grant wonInstigated and oversaw Out-Licensing activities with small, medium and large pharma -
Vp, Research And Business DevelopmentCylene Pharmaceuticals Oct 2011 - Apr 2013Identified opportunity, negotiated and closed deal for acquisition of lead oncology programs Out-Licensed Cylene’s Phase II DNA-quadruplex interacting oncology programFiled IND with FDA: Planned and executed development from pre-IND to phase IIManaged regulatory and technical transfer for early phase clinical trials Oversaw R&D process for preclinical programsInstigated numerous BD conversations. Dealt with Term Sheets, diligence materials and financing discussionsManagement of all corporate legal negotiations and transactionsOversight of Corporate Diligence proceedings -
Director Of Research And Business DevelopmentCylene Pharmaceuticals Feb 2009 - Oct 2011Seek to identify and develop partnering and licensing opportunities in oncology. Influence current and future R&D efforts and focus them on maximizing their short and long-term value. Ensure that the Company’s direction and promotional activities are all supported by strong, well validated science.
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Director Drug Discovery Technologies & Project ManagementCylene Pharmaceuticals Jul 2007 - Dec 2008IND filing – coordinating cross-disciplinary teamsManagement of ADME-PK and IT departmentsKey member of anticancer technology platform development team
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Computational ScientistCylene Pharmaceuticals Aug 2005 - Jul 2007
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Computational ChemistPfizer Sep 2002 - Oct 2004New York, New York, Us -
Computational ChemistAccelrys Oct 2002 - Sep 2004San Diego, Ca, Us -
Computational ChemistUniversity Of Nottingham Nov 2000 - Oct 2002Nottingham, Gb
Sean O'Brien Skills
Sean O'Brien Education Details
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The University Of ManchesterQuantum Chemistry -
The University Of ManchesterChemistry With French
Frequently Asked Questions about Sean O'Brien
What company does Sean O'Brien work for?
Sean O'Brien works for Sisu Pharma
What is Sean O'Brien's role at the current company?
Sean O'Brien's current role is Co-founder and CEO.
What is Sean O'Brien's email address?
Sean O'Brien's email address is dr****@****o.co.uk
What schools did Sean O'Brien attend?
Sean O'Brien attended The University Of Manchester, The University Of Manchester.
What are some of Sean O'Brien's interests?
Sean O'Brien has interest in Science And Technology, Economic Empowerment.
What skills is Sean O'Brien known for?
Sean O'Brien has skills like Drug Discovery, Drug Development, Biotechnology, Oncology, Lifesciences, R&d, Life Sciences, Medicinal Chemistry, Biomarkers, Pharmaceutical Industry, Clinical Development, Chemistry.
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