Dru S. Legare Email & Phone Number

Boulder, Colorado, United States

Boulder, Colorado

Dallas, Texas

Correlative Sciences for clinical studies:o Perform bioinformatics analysis using NGS data obtained using both bulk and single-cell methods.o Research novel technologies to better assess minimal residual disease (MRD) in (acute myeloid leukemia) AML patients as part of correlative sciences.o Manage collaborations for correlative science study projects.o Coordinate logistics and manage companion diagnostic testing for global phase III clinical studies. QC and report companion diagnostic lab resultsClinical study management: o Communicate with clinical study site personnel (e.g., reconcile missing study data, answer questions, patient follow-up, etc.). o Contribute with writing/editing the clinical study-related documents (e.g., study protocol, investigator’s brochure, lab manual, FAQs, etc.).o Prepare presentations and project proposals for CEO and collaborator review.o Renegotiate contracts and increase the proficiency of workflows, which lead to overall budgetary savings.o Initiated the establishment of a quality system for the company by generating SOPs for all departments within the CRO.

Bryan/College Station, Texas Area

• Researched cutting edge technologies within diagnostic field, successfully developed new protocols and presented to management to be incorporated into future business endeavors.• Implemented 18 qPCR assays for molecular diagnostics within the first year in Research and Development at TVMDL.Developed a protocol to couple the use of a magnetic bead-based automated sample processing system with Luminex MagPix® assays.• Successfully led multiple labs in restructuring and streamlining workflows, testing, processes, document creation and management, and client communication. • Assessed and resolved numerous recurrent QC issues within lab environment and brought lab into QA compliance.• Provided QA/QC department with more efficient SOPs by revising and consolidating 80 individual assay SOPs into 4 consolidated SOP documents.• Initiated a collaborative project that transitioned my lab from paper-based record keeping to electronic record keeping which was implemented company wide.• Researched and complied data for reassessment of fee structure for diagnostic testing.

Austin, Texas Area

Project: Create a more efficient bioluminescent reporter for the detection of category A bacterial pathogens.

Albuquerque, New Mexico Area

Assisted Bioassay/Validation specialist with development of methods and assays for validation; performed qPCR assays for contract studies; recorded study data; performed quality control analysis for study data and reports; assisted in writing final study reports.

Albuquerque, New Mexico Area

Project: Successfully monitored the effect of SARS-CoV viral proteins on host proteins within signaling pathways in real-time using fluorescent imaging.Generated a library of fluorescently labeled viral proteins utilizing molecular cloning techniques.

Phd, Biochemistry & Molecular Biology

Bachelor Of Science (Bs), Biology/Biological Sciences, General