Douglas Webber work email
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Douglas Webber personal email
I specialize in developing immunodiagnostic assays using various detection methods, such as ELISA, lateral flow, surface plasmon resonance, western blot, and cell staining. With this expertise, I can customize assays for specific needs, from high-throughput screening to therapeutic purposes.In my extensive research experience, I contributed to developing a monolayer for reliable surface plasmon resonance biosensor assays. I also designed calibrators and controls for environmental health testing in the feed and detergent industries.I was part of a team that developed a bioassay for screening hybridomas' ability to neutralize iNOS, with potential use in sepsis treatment. These projects demonstrate my versatility in applying assay development to diverse fields and applications.Driven by a passion for producing high-quality products, I continually push the limits of assay development to make a meaningful impact in areas with limited effective therapies or assays. My specialties include optimizing various assays, purifying antibodies under GMP, and cell culture, among others.
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Scientists IvGenalyte, Inc. Mar 2022 - PresentSan Diego, California, UsDeveloping clinical assays that can be regenerated , using biosensors. The system is the Maverick, which uses the plasmon resonance rings. I have been able to stabilize the the regeneration with the using backfill molecules. I am currently help develop assays for the 20 most commonly ordered clinical test to put on the Maverick assay system. -
Senior ScientistMagnabioanalytics Mar 2009 - Mar 2022Plan, develop and coordinate staff for production and final testing of lateral flow assay, implement quality assurance protocols for final production. Development of a new process to remove red blood cells for the liquid portion of the blood (plasma) without using a centrifuge. 1. Development a Blood Separation, using magnetic particles to cause agglutination of RBC.2. Luteinizing hormone (LH), Follicle stimulating hormone, lateral flow assay quality testing for CE stamp.3. Testing Thyroid stimulating hormone (TSH) for 510K approval process.4. Operate and maintain the AVDIA Centaur CP (auto-analyzer as a reference for lateral flow assays).
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Team Leader / Senior ScientistResearch & Diagnostic Antibodies Jul 2005 - Dec 20081. Therapeutic antibody development a. Chimeric antibody development, production, scale-up, and purification. b. Developing and testing new animal model for SIR/Sepsis conditions without using cecal ligation and puncture methodology 2. Co-Development of sandwich ELISA for clinical use a. Plasma of septic patients. b. Initial Quality Control and reliability studies 3. Developed lateral flow test for potential point of care (POC) device. a. Conjugation of antibodies to paramagnetic and latex particles b. Feasibility testing 5. Co-authored SOP documentation for products (EIA and dipstick assay).6. Co-authored patents 7. Hybridoma cell culturea. Produce serum free hybrids.b. Scale-up of hybrids using a 5 liter bioreactorc. purification of monoclonals using protein A chromatography in GLP environment.8. Initial quality control of EIA assay -
ConsultantDsx Therapeutics May 2003 - Jun 2005
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Post-Doctoral FellowUcla 2001 - 2005Los Angeles, Ca, UsAs Postdoctoral fellow, I was responsible for running the research project on effects of carbon monoxide development of hearing, writing grants, and writing and editing all primary publications. I was also responsible for helping running the biochemistry laboratory for medical school.1. Found increase in nitric oxide synthase (NOS) in the caudate- putamen after different mild CO exposure paradigms (pre-natal, pre and post-natal, or post-natal) in development. 2. Examined the auditory deficits that occur with exposure to CO during development. 3. Found a potential mechanism for CO exposure causing oxidative stress using the Fenton Reaction during development. -
Graduate StudentTulane Medical Center 1996 - 2001
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Assay TechnicianResearch & Diagnostic Antibodies Oct 1992 - Jun 1996Developed and produced monoclonal and/or polyclonal antibodies for stock and custom products (peptide synthesis, conjugation, and screening, assay development).
Douglas Webber Skills
Douglas Webber Education Details
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Tulane UniversityNeuroscience -
San Francisco State UniversityCell & Molecular Biology
Frequently Asked Questions about Douglas Webber
What company does Douglas Webber work for?
Douglas Webber works for Genalyte, Inc.
What is Douglas Webber's role at the current company?
Douglas Webber's current role is Genalyte.
What is Douglas Webber's email address?
Douglas Webber's email address is dw****@****mni.net
What schools did Douglas Webber attend?
Douglas Webber attended Tulane University, San Francisco State University.
What skills is Douglas Webber known for?
Douglas Webber has skills like Immunoassays, Antibody Development, Elisa, Western Blotting, Confocal Microscopy, Fluorescence, Cryostat, Surgery, Lifesciences, Biochemistry, Biotechnology, Neuroscience.
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