David Silberstein, Ph.D. Email & Phone Number

San Carlos, California, United States

Novato, California

- Led downstream process characterization efforts for a unit operation of an AAV gene therapy product.- Investigated new chromatography resin modalities to expand gene therapy purification platform.- Designed and executed a study that doubled the capacity of a gene therapy purification step.- Provided expertise in tech transfer from process development group to manufacturing pilot plant.- Coordinated lab work for an accelerated AAV gene therapy in a downstream process development context.- Contributed to the implementation of a 5S system in downstream process development labs.

Vacaville, Ca

- Designed and transferred purification process for a DNA error correction enzyme.- Developed new assays for DNA error correction effectiveness.

Focused on production, purification, and techno-economic analysis of alpha-1 antitrypsin produced in a transient transfection plant model.

Los Angeles, California

Validation Specialist for Neutrogena Corporation, Cleaning Validation Group (October 2013 - August 2014)• Developed and executed successful Kettle Sanitization Validation project• Assisted in development of documents including Validation Protocols and SOPs for Kettle Cleaning Validation project• Assisted in execution of Kettle Cleaning Validation projectValidation Specialist for Baxter Bioscience (September 2012 - October 2013)• Assisted in validation of critical systems and building automation system during facility upgrades• Drafted validation protocols and final reports for critical systems, building automation system, and facilities• Assisted in validation of Clean-In-Place skid expansions for high-volume manufacturing facilities• Coordinated improvements to facility GMP

Greater Los Angeles Area

Provided tutoring services for middle school and high school mathematics and chemistry students. Responsibilities included planning individual lessons and coordinating scheduling with students.

University Of California, Los Angeles

Sales associate at UCLA textbook store. In charge of restocking and helping customers find their books.

Doctor Of Philosophy (Ph.D.), Chemical Engineering

Bachelor Of Science (B.S.), Chemical And Biomolecular Engineering

Activities and Societies: American Institute of Chemical Engineers, Tau Beta Pi