Eric Boyden Email & Phone Number

Woburn, Massachusetts, United States

Responsible for scientific strategy and leading R&D projects, including:• Development and launch of LoopCapTM chemistry for targeted short-read NGS of both DNA and RNA using molecular inversion probes (MIPs)• Modifications to LoopCap chemistry to enable efficient and uniform viral RNA capture for pathogen surveillance (used by LabCorp for SARS-CoV-2 surveillance)• Refinements to LoopCap chemistry to enable use of as little as 1 ng of input DNA (cell-free or FFPE) for somatic assays or a 1-day workflow for germline assays• Long-target LoopCap for sequencing via PacBio and Oxford Nanopore platforms• Improvements to the MIP design and NGS data analysis informatics pipelinesLead or contributing author on numerous posters presented at scientific conferences including AGBT, ASHG, and AMPSupervisor of R&D Scientist

Cambridge, Ma

• Lead member of a collaborative Research & Development team responsible for the development and technical validation of clinical genetic assays, as well as basic biology and technology research• Proficiencies include molecular biology, bioinformatics, liquid handling automation, project leadership, supervision of scientists & research associates, technical writing, and training of clinical laboratory staff• Led the development of the first commercial NGS-based spinal muscular atrophy (SMA) carrier screening assay• Developed liquid-handling automation for a NGS-based pre-implantation genetic screening (PGS) assay• Led the development of a hybridization capture-based medical exome screening assay• Led the development of a molecular inversion probe (MIP) capture-based expanded carrier screening assay• Lead inventor on 3 patents• Lead or contributing author on numerous posters presented at the annual American Society of Human Genetics conference• Supervisor of Senior R&D Scientist & two Senior Research Associates

Greater Boston Area

• Led the discovery of KIF22 as the causative gene in spondyloepimetaphyseal dysplasia with multiple dislocations (leptodactylic-type) via linkage analysis and whole-exome sequencing• Led the discovery of PTPN11 as the causative gene in metachondromatosis via linkage analysis and targeted NGS• Trained others in Illumina and Life Technologies SOLiD NGS data analysis, NGS library preparation and capture array design, and high-density SNP chip-based linkage analysis• Mentored a graduate student and two summer post-baccalaureate researchers

Greater Boston Area

Greater Boston Area

Teaching fellow for two sections of the undergraduate laboratory course LS1B: Genetics, Genomics, and Evolution

Doctor Of Philosophy (Phd), Genetics

Discovered and characterized the highly polymorphic and multi-allelic Nalp1 family of murine genes, which control sensitivity to anthrax.

Bachelor Of Science (Bs), Cell/Cellular And Molecular Biology

Summa cum laude w/Honors and Minor in Mathematics