Ed Higgins Email & Phone Number

Philadelphia, Pennsylvania, United States

Boston, Massachusetts, United States

My role is to work with end-user scientists in Biotech and Pharma to provide unique solutions that streamline complex workflows enabling greater pursuit of their experimental goals. As a valued partner I support their efforts in making breakthrough discoveries combating complex diseases in the hopes of making the world happier and healthier.My position supports Biosciences Division portfolio which includes the Thermo Fisher, Applied Biosystems, Invitrogen, GIBCO, and PeproTech brands. The products I cover include reagents, instruments, and consumables from across the division’s six business units: Molecular Biology; Protein and Cell Analysis; Antibodies and Immunoassays; Synthetic Biology; Sample Preparation; and Cell Biology.

- Creates curated curriculums and immersive class experiences to prepare students for their standardized test (MCAT/DAT/OAT). - Provides individualized instruction and coaching in the biological sciences, physical sciences, and verbal content/critical thinking skillsets.- Awarded MCAT Teacher of the Year 2018 – selected by Kaplan management for outstanding MCAT tutoring for the year based on customer feedback

Translational Medicine ResearcherMy primary research interests involve mechanisms of the colorectal cancer (CRC) tumor microenvironment (TME), specifically, involving the development of an immunosuppressive TME. Newly developed targeted therapies, such as checkpoint inhibitors, have revolutionized the treatment of many late stage solid cancers winning the Nobel prize in 2018. However, most CRC does not respond to these treatments, my research focuses on why checkpoint inhibitors do not work in CRC and what other mechanisms CRC uses to establish an immunosuppressive TME. Our hypothesis is that dysregulation of tumor cysteine metabolism causes the aberrant upregulation of endogenous hydrogen sulfide (H2S) production and the excess H2S promotes/supports an immunosuppressive TME by limiting maturation of resident dendritic cells/macrophages thereby stopping T-cell activation. - Served under the direction of the principal investigator in understanding the mechanisms of intercellular communication between the cells in the colorectal tumor microenvironment - Contributed to the understanding of colorectal cancer immunosuppressive tumor microenvironment, and using new treatments combined with existing checkpoint inhibitors to convert immunosuppressed colorectal cancer cells into immunoreactive T-cell responders.- Collaborated with multidisciplinary translational teams to impact public health outcomes, achieved through resource-sharing, securing extramural funding, and disseminating research findings.- Prepared manuscripts, budgets, and grant applications in alignment with research projects and related support activities. - Presented poster abstracts for academic and industry feedback at the McLaughlin Symposium (2019) and Digestive Disease Week (2019 & 2020).

- Provided a top-tier, engaging customer experience by developing strong relationships with clients and creating optimal technology solutions suiting current needs.- Inventory Lead – selected for inventory lead of the computer and tablet section of best buy store where responsibilities included pricing and management of sales promotions.- Selected at store MVP Twice – (2011 and 2013) – recognized for providing excellent customer experience as well as outstanding team member.

Directed 12-member staff and led sales, business development, and procurement for all sales divisions – resellers and end users. Served on Board of Directors and helped establish strategic 3-year plan. Took on responsibilities of terminated VP of Sales. Managed daily sales activities, created sales forecasts and budgets, and led weekly staff meetings. Endorsed Six Sigma training.- In less than 2 years, generated $5M+ in additional sales revenues to achieve MasterWorks’s largest revenue year.- Added $2M per year in revenue through development of new HP Authorized Parts Reseller vendor contract.- Significantly expanded sales by presenting existing products and solutions to new customers, including executive presentations and facility tours.- Improved Internal Rate of Return 10%+ by spearheading first software upgrade since 2000.- Boosted sales by developing key performance indicators to drive accountability and gauge sales performance for calls, customer touches, quotes, and quote conversion.- Initiated changes to MW logo and website design.- Achieved costs savings by managing vendor relationships and expanding supplier base.- Created commission plan; coached sales reps on phone sales, closing tactics, and account-development strategies.- Formalized sales process and documented process flows using value stream mapping to eliminate process waste.

Stepped up when needed and volunteered to focus on accounting and finance due to company downturn and firing of controller. Supervised all accounting functions including payables, receivables, payroll, pricing, purchasing, and inventory control.- Initiated first MW yearly departmental budgets and instituted monthly budget and P&L reviews. Prepared monthly closing cycles, created cash flow forecasts, authorized checks, set pricing strategy, established monthly specials, and designed monthly sales-out reporting for HP review.- Played key role in successful plan that paid off $3M+ in debt in 2 years and brought MW out of workout in 18 months. Helped present MW to new banks and negotiated terms.- Generated $3M in 2006 by securing new HP vendor. Revenue grew to $5M in 2007 with an average of $4M in successive years.- Landed contract that brought in $8M+ in annual revenue as one of two HP remarketing distributors in 2006.- Procured $10M+ in inventory for MW sales and managed inventory, meeting aging and turn targets.- Volunteered to lead MW team that set Operating Level Agreements (OLAs) for procurement and sales to foster better sales, operations, and procurement communication.- Reduced monthly variable expenses 20%+ through cost-cutting measures during workout.

Oversaw all sales and purchasing operations, including sales coaching, goal setting, purchasing, inventory management, vendor qualification and quarterly reviews, and relationship management with HP.- Led MW to its second-highest sales year, reaching $19M in 2004.- Brought in new product lines to diversify MW sales channels and become one-stop shop for HP products.- Increased bottom line 10% through creation of vendor matrix to identify the most cost-efficient suppliers.

Developed and managed accounts that generated $2M in sales and accounted for 30% of the company’s revenues.- Consistently ranked in the top 3 among national sales force.- Achieved greater than 100% of quota for all years in position.- Won trip and recognition as #1 sales rep in 2000.

Doctor Of Philosophy - Phd, Oncology And Cancer Biology

Bachelor Of Science - Bs, Cell/Cellular And Molecular Biology

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