Emmanuel Debrand Email & Phone Number

Gerzat, Auvergne-Rhône-Alpes, Fr

Greater Clermont-Ferrand Area

Pirey, Bourgogne-Franche-Comté, France

Birmingham, United Kingdom

Debrand E, Lykoudi A, Bradshaw E, Allen SK. A Non-Invasive Droplet Digital PCR (ddPCR) Assay to Detect Paternal CFTR Mutations in the Cell-Free Fetal DNA (cffDNA) of Three Pregnancies at Risk of Cystic Fibrosis via Compound Heterozygosity. PLoS One. 2015 Nov 11;10(11):e0142729. doi: 10.1371/journal.pone.0142729. PMID: 26561302; PMCID: PMC4641687.

Birmingham, England, United Kingdom

Cyto- and molecular diagnosis of genetic defects (developmental disorders, hereditary cancers, cystic fibrosis, Duchenne Muscular Dystrophy etc.)

Birmingham, England, United Kingdom

Modernising Scientific Career Pilot Training Scheme in clinical GeneticsWork-based training in cyto- and molecular diagnosis of genetic defects.MSc in clinical sciences at University of Nottingham

Leicester, England, United Kingdom

Talin group led by Pr D. R. CritchleyRole of Talin 2 in mouse development, cell adhesion and motility.Debrand E, Conti FJ, Bate N, Spence L, Mazzeo D, Pritchard CA, Monkley SJ, Critchley DR. Mice carrying a complete deletion of the talin2 coding sequence are viable and fertile. Biochem Biophys Res Commun. 2012 Sep 21;426(2):190-5.Debrand, E., El Jai, Y., Spence, L., Bate, N., Praekelt, U., Pritchard, C.A., Monkley, S.J. and D.R. Critchley (2009) Talin 2 is a large and complex gene encoding multiple transcripts and protein isoforms. FEBS Journal, in press.

Cambridge, England, United Kingdom

Laboratory of Chromatin and Gene Expression, led by Dr P. FraserRole of intergenic transcription, chromatin remodelling and nuclear compartments in the regulation of the Beta-globin locus.Debrand E, Chakalova L, Miles J, Dai YF, Goyenechea B, Dye S, Osborne CS, Horton A, Harju-Baker S, Pink RC, Caley D, Carter DRF, Peterson KR, Fraser P. An intergenic non-coding RNA promoter required for histone modifications in the human β-globin chromatin domain. PLoS One. 2019 Aug 14.Chakalova, L., Debrand, E., Mitchell, J., Osborne, C. and P. Fraser (2005) Replication and transcription: shaping the landscape of the genome. Nature Review Genetics, 6: 669-677.Osborne, C.S., Chakalova, L., Brown, K.E., Carter, D., Horton, A., Debrand, E., Goyenechea, B., Mitchell, J.M., Lopez, S., Reik, W. and P. Fraser (2004) Active genes dynamically colocalize to shared sites of ongoing transcription. Nature Genetics 36: 1065-1071.Chakalova, L., Osborne, C.S., Carter, D., Debrand, E., Goyenechea, B., Horton, A., Miles, J. and P. Fraser (2004) Developmental Regulation of the β-Globin Gene Locus, In P. Jeanteur (Ed.), Progress in Molecular and Subcellular Biology, Epigenetics and Chromatin serie, Springer-Verlag Berlin, Heidelberg, Germany.

Paris, Île-De-France, France

Mouse Molecular Genetics Unit, led by Pr Philip Avner.Characterisation of the mouse X inactivation centre: functional analysis of the region 3' to the Xist gene by knock-out in Embryonic Stem Cells.Morey, C., Navarro, P., Debrand, E., Avner, P., Rougeulle, C. and P. Clerc The region 3' to Xist mediates X chromosome counting and H3 Lys-4 dimethylation within the Xist gene. EMBO J., 23: 594-604.

INSERM U316 team 4 “Genetics of autism” led by Pr C. Andrès, University of Tours Medical School, Tours, France.“Generation of molecular constructs for the in vivo over-expression of the Omgp (oligodendrocyte-myelin glycoprotein) gene, a candidate in autism.”

Paris, Île-De-France, France

Molecular Biology, Human Genetics and genome engineering.Tutorials and laboratory demonstrations in Genetics and Molecular Biology for second and third years undergraduate students in genetics.

Paris, Île-De-France, France

Doctorant, Institut Pasteur + Moniteur-normalien/ATER université Paris VI

Manager En Stratégie Et Développement De Projet Digital, Product Management, Rncp Niveau 7

Titre Professionnel Concepteur Designer Ui, Web Page, Digital/Multimedia And Information Resources Design, Titre Rncp Niveau 6 ✅

Front-end web design and development

Phd (Hons), Cellular And Molecular Genetics

Debrand, E., Chureau, C., Arnaud, D., Avner, P. and E. Heard (1999). Functional analysis of the DXPas34 locus: a 3’ regulator of Xist.

Bsc And Msc, Philosophy And History Of Science

both degrees with Honours

Master, Biology-Biochemistry-Genetics

degree with honours