Hard-working, self-driven Chemist experienced in organic and inorganic synthesis, including developing new cancer drugs, reviewing existing compounds and polymer synthesis for biomimetic research. Adept at recording results and analysis. Specialise in synthesis, literary research and isolation of defined chemical targets.
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Associate ScientistAstrazenecaFalls Church, Va, Us -
Process Development AssociateNovavax Nov 2024 - PresentGaithersburg, Maryland, United States -
Associate ResearcherVandstrom Jul 2024 - Nov 2024Gaithersburg, Maryland, United StatesLed the synthesis and analysis of complex experimental findings, contributing to the advancement of biotechnological research and development initiatives, and significantly advancing the field of material science.Managed large-scale plasmid expression through fermentation, handling volumes up to 450 L using BL21-DE3 bacterial cells, while ensuring compliance with stringent biosafety standards.Employed chromatography, spectroscopy, and protein assays (including SDS-PAGE and Western Blot) to identify fundamental product properties crucial for research and development.Developed a Python script for the automated analysis of data from stopped-flow light scattering instruments, reducing manual processing time and increasing accuracy.Improved visualizations for dynamic light scattering (DLS) measurements, providing clearer and more insightful data presentations.Analyzed data from fermentation runs to develop Python-based solutions that optimize bioprocessing methods, improving yield and efficiency.Assisted in the creation of a Python script for analyzing scientific data from a fluorescence imager, enhancing result visualization and enabling precise quantification of data from pixel intensities.Conducted advanced microscopy techniques, including negative stain and cryo-EM, for nanoparticle classification and 3D reconstruction using specialized software on a Linux HPC system, supporting detailed classification and understanding of nanoparticle behavior. -
Laboratory Technician IiVandstrom Mar 2023 - Aug 2024Gaithersburg, Maryland, United StatesConduct polymer/ organic synthesis and purification per company Standard Operating Procedure (SOP), including small-molecule, amphiphilic polymer and membrane additive synthesis. Perform in-depth characterisation using various analytical techniques and responsible for documentation of experiments, data and results using lab notebooks, reports and presentations. Conducted material characterisation using chromatography and spectroscopy and analysed said data using Python and OriginLab. Per the SOP, protein expression was independently carried out using in-house fermentation methods and purification for downstream biochemical/ biophysical analysis and performed scale-up activities associated with protein and exosome production. Work collaboratively with other lab members to perform and analyse additional experiments outside the protein chemistry and engineering scope. Participate in good lab practice (GLP) and follow company policy and Occupational Safety and Hazards Administration (OSHA) regulations. -
Polymer Lab Technician IVandstrom, Inc. Jul 2022 - Mar 2023Gaithersburg, Maryland, United StatesConduct polymer/ organic synthesis, including small molecule and amphiphilic polymers and membrane additive synthesis. Performed in-depth characterisation using various chromatography and spectroscopy techniques, conducted robust data analysis on experiments, and documented technical progress/ results. Maintained instruments and troubleshooted in the case of instrument failure. -
Research AssistantVirginia Commonwealth University Jan 2020 - Mar 2022Richmond, Virginia, United StatesConducted literary investigation of chemical journals regarding the project on hand. Analysed existing platinum and cobalt formulas for bioactivity against various viruses and cancers and worked to develop less cytotoxic alternatives to current metallodrugs. Collected data on drug interaction with the target molecule. Synthesised the molecule from commercial starting materials and conducted various forms of spectroscopic analysis. Prepared biological assays with a mimetic of target and in vitro studies. Assisted the Principal Investigator by providing required reports. Adhered to proper academic and lab safety procedures.
Eduardo Pacheco Education Details
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Data Science -
Biochemistry, Biophysics And Molecular Biology
Frequently Asked Questions about Eduardo Pacheco
What company does Eduardo Pacheco work for?
Eduardo Pacheco works for Astrazeneca
What is Eduardo Pacheco's role at the current company?
Eduardo Pacheco's current role is Associate Scientist.
What schools did Eduardo Pacheco attend?
Eduardo Pacheco attended University Of Michigan, Virginia Commonwealth University.
Who are Eduardo Pacheco's colleagues?
Eduardo Pacheco's colleagues are Alberto Ramirez, Tasnim Sultana, Elena Fuchs, Colleen Sico, Lucie Bartůňková, Jana Sachova, Jasmin Telo.
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Eduardo Pacheco
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