Ehsan Alvandi, Phd Email & Phone Number

Sydney, New South Wales, Australia

• Conducted advanced molecular experiments in Personalised Immunotherapy Platform (PIP) to stratify the patients and treatments based on the mutational burden (genomic) and gene expression profile (transcriptomic) of the tumour• Performed the most advanced next-gen sequencing platform (Genexus System) in the Oncomine Clinical Research Grant project to tackle the overdiagnosis and underdiagnosis of melanoma • Techniques: Illumina NGS, Tissue Microarray (TMA) and Single-cell RNA sequencing (scRNA-seq)• Trained PhD students

School Of Medicine, Western Sydney University, Nsw, Australia

• Led the problem-solving and critical thinking sessions, provided training and personalised guidance and mentorship to enhance practical abilities and decision-making among students

School Of Medicine, Western Sydney University, Nsw, Australia

Completed four distinct projects concurrently on cancer and diabetes spanning cell and molecular biology, animal models, and clinical data analytics. PhD Program, awarded the Best Paper (2023), Best Presenter (2022), WSU library fund for publication (2022), and postgraduate research scholarship (2019):• Conducted complex in vitro experiments using primary cell models of human pancreatic islets and colon cell lines under varying conditions and exposures to study the Type 2 Diabetes progression• Employed high-throughput advanced molecular genetic techniques using OpenArray panels, ddPCR, and real-time qPCR on various tissues and cells• Utilised machine learning approaches on RNA sequencing data to compare transcriptome signatures• Prepared animal ethics application, executed a mouse model study on three interventions, measured physiological and molecular parameters, and conducted behavioral tests for neuromuscular changes• Processed, standardised, and consolidated real-world datasets into a comprehensive database for 3609 patients over 26 years. Conducted extensive data analyses on Early-onset Colorectal Cancer in collaboration with NSW Concord Hospital Colorectal Surgical Unit and Westmead Hospital• Provided mentorship to the students and young researchersAchievements:• Designed a custom transcript panel to study the gene expression profiles in pancreatic islets• Elevated EOCRC awareness, advocating for a reduction in Australia's National Bowel Cancer Screening age through local and international conferences and publications• Awarded both Best Presenter and Best Paper in establishing short-chain fatty acids as a promising colorectal cancer prevention biomarker through a comprehensive meta-analysis

School Of Science, Western Sydney University, Nsw, Australia

• Provided mentorship to the students to perform the lab experiments and data analyses• Evaluated assignments and reports; provided feedback and troubleshooting

Perth, Western Australia, Australia

Project: Developing Machine Learning Models to Predict the Risk of Hospital-Acquired Complications (HACs) including processing the real-world hospital databases, conducted statistical analyses, and developing the ML models

School Of Nutritional Science And Dietetics (Snsd)

Teacher at postgraduate level, Supervisor of 50+ MSc/PhD research projects, Mentor of 100+ postgraduate students, and Manager of the Cellular and Molecular Laboratory[TUMS is internationally acclaimed as the leading institute for medical research in Iran. SNSD is the top school in the country focusing on nutrition in education and research.]• Planned the step-by-step procedure of molecular experiments specific for each research project based on the project aims• Characterised genes/sequences and designed qPCR primers/probes using genome databases (NCBI GenBank, AceView, Ensembl, GeneCards, and SNPedia) and software (Chromas and SnapGene)• Performed the set-up and execution of molecular genetics techniques including quantitative real-time PCR, PCR-RFLP, and DNA sequencing preparation• Designed and implemented training programs and workshops, focusing on safety procedures, experimental protocols, primer/probe design, data analysis, and report preparation• Assessed the quality control of experiments/analyses and offered troubleshooting solutions• Developed, optimised, and evaluated protocols and new techniques, calibrated the equipment, managed the supplies, oversaw the day-to-day lab activities, and prepared reportsAchievements:• Managed to save hundreds of dollars per institute’s project by optimising the experiments to consume the resources with highest efficiency, which also helped offering competitive prices and absorbing $20,000 from other institutes to perform their experiments in our laboratory• Strategically negotiated with suppliers for 25% cost saving in buying new equipment for the lab• Developed a cost-effective alternative to TaqMan probes in real-time qPCR, also inspired other labs • Contributed as co-author in more than 20 articles from the research projects conducted in the lab• Earned Employee of the Year award in 2015

Tehran, Tehran, Iran

[The leading pharmaceutical company in Iran]• Coordinated group meetings with specialists, and managed the exhibition booths in two conferences

Tehran, Tehran, Iran

[Pars Tash Azma was then the exclusive distributor of BAG GmbH company HLA-typing products in Iran]• Played a pivotal role in establishing the company and its product brand by leading the training sessions and workshops introducing a new molecular (immunogenetic) method for organ transplantation HLA-typing, evolved into providing service and support to 80% of potential customers nationwide• Authorised signatory of the ministry of health, and commerce paperwork for importing new supply• Liaised with the technical team of the source company for updates and troubleshooting adviceAchievements:• Selected & represented the company to attend two workshops at the source company in Germany• Helped design a new serology plate (Histo Tray Disease) for the local market in Iran• Enhanced the product worksheet for better user-friendliness and compatibility with the software[My tenure in this role: Apr 2006 - May 2007 (part-time), Jun 2007 - Jan 2010 (full-time)]

Tehran, Tehran Province, Iran

My MSc thesis project at TUMS School of Medicine, Medical Genetics Department that turned into a nationwide clinical study [TUMS is internationally acclaimed as the leading institute for medical research in Iran.]• Coordinated a nation-wide clinical study in collaboration with the endocrinology departments of multiple hospitals, pathologists, thyroid surgeons, and other research institutes• Planned and executed patient recruitment, screening and informed consent process, data collection, genetic counselling, and patient follow-up while addressing ethical considerations related to the hereditary diseases• Executed all the experimental phases from DNA isolation to PCR and DNA sequencing analyses• Generated patient reports and referral to specialists and provided in-depth explanations to patients• Enlisted family members of identified hereditary patients to undergo a similar process aimed at identifying carriers of the mutationAchievements:• Developed the detailed step-by-step protocol for managing the hereditary Medullary Thyroid Cancer including detecting the germ-line mutations in the patients and tracking them in their family members/offspring to refer them for prophylactic thyroidectomy• Presented the findings in the official journal of American Thyroid Association and at two conferences • Selected as the representative of young researchers for a live TV science program on the national broadcasting channel• Achieved the 1st rank among 854 candidates in the National MSc Entrance Exam, 2003

Tehran, Tehran Province, Iran

[Volunteered before and throughout the first year of my MSc studies] [School of Public Health and School of Medicine]• Contributed to two Breast Cancer research projects, employing molecular genetics techniques and delivering results to the chief investigator

Doctor Of Philosophy - Phd, Medicine

Achievements: • Best paper: Western Sydney University School of Medicine 2023 best HDR paper • Best presenter: Western Sydney University.

Master'S Degree, Human/Medical Genetics

Achievements: • Ranked 1st among 854 candidates in the National MSc Entrance Exam (2003) • Selected as the representative of young.

Bachelor'S Degree, Biology/Biological Sciences, General