Eleanor Eiffe Email & Phone Number

Sydney, New South Wales, Australia

Sydney, New South Wales, Australia

I use Python and React to build tools for standardising and analysing complex healthcare data. I specialise in translating AI solutions into the next generation of Evidentli products.

Sydney, New South Wales, Australia

• I joined the Cellular and Genetic Medicine Unit (CGMU) to manage a CRC-P funded drug development program conducted in collaboration with industry partner TroBio Therapeutics. I have planned, implemented, and managed a.
• Designed more than 400 novel tropomyosin-targeting compounds via in silico docking and de novo design with tropomyosin homology models;
• Identified ligands for tropomyosin isoforms via high throughput virtual screening of commercial compound libraries;
• Developed synthetic routes for novel compounds and managed the external chemistry team conducting compound synthesis;
• Established and developed relationships with CRC-P subcontractors providing chemistry, biology, and speciality software services;
• Collaborated with CGMU heads to develop a screening and lead selection strategy to identify compounds with the desired biological activity and favourable druglike properties; and

Sydney

• I joined this oncology drug development company to manage the hit-to-lead development phase of a novel cancer treatment technology. While drug discovery remained my primary focus, my role expanded to encompass.
• Designed small molecule libraries for drug discovery projects and managed the external team conducting chemical synthesis;
• Ensured the on-time delivery of high quality GMP API while on-site at a contract manufacturing organisation;
• Prepared Chemistry, Manufacturing and Controls sections of a successful IND submission and IND update to the US FDA;
• Prepared six patent applications and worked with patent attorneys to manage Kazia’s IP portfolio; and
• Presented at national and international medicinal chemistry conferences.

• I worked with both the School of Chemistry and the School of Physics at UNSW to help each school overhaul their systems for managing Health & Safety (HS) documentation. During this time, I:
• Ensured that both Schools passed their respective HS audits;
• Prepared, reviewed and established systems for the management of HS documents; and
• Implemented UNSW HS Policy, ensuring that the Schools complied with NSW law and the relevant Australian Standards.

• After submitting my thesis, I worked with my PhD supervisor as a part-time research associate. This role allowed me to build on the skills I developed during my PhD research via:
• Mentoring undergraduate, Honours and PhD students;
• Preparation of grant applications and research papers; and
• Synthesis and characterisation of novel small molecules

• During my PhD studies, I was employed on a short-term basis to assist with preparations for an external audit. This involved:
• Reviewing and updating documents to meet GMP standards;
• Processing and archiving the results of Quality Control analyses; and
• Timely analysis of raw materials, finished products, and product packaging following approved methods.

• I joined this pharmaceutical company as a research and development chemist in a lab-based role that encompassed:
• Design and synthesis of novel drug candidates;
• Process development and scale-up for lead compounds; and
• Training and mentoring of junior laboratory staff.

Doctor Of Philosophy (Ph.D.), Organic Chemistry

Project: The Synthesis of Novel, Biologically Active Isoflavone Analogues

Bachelor Of Science (Bsc) (Honours), Organic Chemistry

Project: Peptide-Appended Porphyrin Anti-Cancer Agents

Bachelor Of Technology (B.Tech.), Forensic And Analytical Chemistry