Eli Chapman Email and Phone Number
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Eli Chapman is a Associate Professor at University of Arizona College of Pharmacy. He possess expertise in molecular biology, protein purification, biochemistry, protein expression, protein chemistry and 10 more skills.
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Associate ProfessorUniversity Of Arizona College Of PharmacyTucson, Az, Us
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Associate ProfessorUniversity Of Arizona College Of Pharmacy Jul 2018 - PresentTucson, ArizonaDepartment of Pharmacology and Toxicology - Drug Discovery and Development
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Assistant Professor And Faculty Of The Kellogg School Of Science And TechnologyThe Scripps Research Institute Sep 2010 - Jul 2012Assistant Professor of Molecular Biology with extensive experience in recombinant DNA techniques, bacterial genetics, organic chemistry, protein expression, protein purification, and protein characterization.Courses Taught:Structural Biology Core Course• Protein folding in macromolecular machines• Protein unfolding in macromolecular machinesBiophysics Core Course• Chemical biology as a tool for biophysical studiesCell Biology Core Course• Subcellular localization of protein aggregates• Chemistry Journal Club -
Assistant Professor Of Molecular BiologyThe Scripps Research Institute Feb 2007 - Jul 2012• Developed a protocol to study protein localization in vivo using unnatural amino acid mutagenesis• Developed a bacterial strain rescued by a fluorescent copy of FtsZ• Studied GroEL localization and dynamics in vivo using fluorescent amino acid incorporation• Co-wrote an RO1 with Prof. Michael Burkart (UCSD) in response to an RFA to develop tools for imaging proteins in vivo• Initiated studies to label and study multiple proteins simultaneously in vivo using chemistry and semi-rational evolution of the CoA biosynthetic pathway
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Nrsa Post-Doctoral Fellow With Prof. Art HorwichThe Scripps Research Institute Jul 2004 - Feb 2007• Purchased equipment and set up a new lab for Prof. Horwich• Employed a combination of chemistry and genetics to engineer a GroEL variant sensitized to a small molecule• Used the GroEL-inhibitor pair to characterize GroEL’s ATP-binding requirements• Developed a fluorescent GroEL-GroES assay for high-throughput screening of the entire chaperonin reaction cycle• Screened a library of ~750,000 molecules for inhibition of GroEL• Used a series of biochemical and cell-based assays to further analyze inhibitors discovered• Synthesized panels of inhibitors based on scaffolds discovered during screening efforts
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Hhmi Postdoctoral Associate With Prof. Art HorwichYale University School Of Medicine Dec 2002 - Jul 2004• Used a combination of molecular biology techniques to generate a bacterial strain rescued by a temperature sensitive GroEL variant• Used the developed strain to study the physiological function of GroEL• Used multi-dimensional protein identification technology (MudPIT) to characterize the substrates of GroEL• Biochemically characterized a subset of proteins discovered proteomically• Developed a new in vivo model for a global GroEL action -
Graduate Student With Prof. Chi-Huey WongThe Scripps Research Institute Jun 1998 - Oct 2002• Cloned, expressed, and purified sulfotransferases for biochemical, synthetic, and medicinal chemistry studies• Developed a general colorimetric assay to study sulfotransferases• Used a recombinant sulfotransferase to synthesize sulfated carbohydrates• Developed a model of the sulfotransferase transition state using linear free-energy analysis • Developed inhibitors based on proposed transition state model• Developed a fluorescence-based high-throughput assay to screen a small-molecule library for sulfotransferase inhibitors• Screened a library of ~50,000 small molecules• Resynthesized and characterized hits from screening efforts
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Laboratory TechnicianUs Army May 1992 - May 2000• Collected and analyzed various biological specimens from patients• Deployed a mobile medical laboratory during field operations -
Graduate Student With Prof. James LeightonColumbia University Aug 1996 - Jun 1998• Developed the first example of a transition metal catalyzed silylformylation reaction on an alkene as an entry into 1,3-polyols -
Summer Research Fellow With Prof. Jon ThorsonMemorial Sloan-Kettering Cancer Center Jun 1996 - Aug 1996• Helped set up and establish a new lab for Prof. Thorson• Cloned, over-expressed, and purified glycosyltransferases for glycorandomization -
Undergraduate Researcher With Prof. Peter SchultzUc Berkeley Nov 1993 - Jun 1996• Synthesized unnatural amino acids for in vitro unnatural amino acid mutagenesis• Developed and employed in vitro unnatural amino acid mutagenesis to study protein stability and catalysis
Eli Chapman Skills
Eli Chapman Education Details
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Chemistry
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Columbia UniversityChemistry -
Chemistry
Frequently Asked Questions about Eli Chapman
What company does Eli Chapman work for?
Eli Chapman works for University Of Arizona College Of Pharmacy
What is Eli Chapman's role at the current company?
Eli Chapman's current role is Associate Professor.
What is Eli Chapman's email address?
Eli Chapman's email address is ec****@****pps.edu
What schools did Eli Chapman attend?
Eli Chapman attended The Scripps Research Institute, Columbia University, Uc Berkeley.
What skills is Eli Chapman known for?
Eli Chapman has skills like Molecular Biology, Protein Purification, Biochemistry, Protein Expression, Protein Chemistry, Cell Biology, Drug Discovery, Organic Chemistry, Assay Development, Laboratory, Genetics, Chemistry.
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Eli Chapman
Software Development Intern | Quality Assurance & Test Automation With PlaywrightTopeka, Ks -
Eli Chapman
New York, Ny4rga.com, tubemogul.com, gmail.com, celtra.com3 +151065XXXXX
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