The Train2Target project is focused on a new generation of innovative antibacterials treatment in order to counteract infections by multi-drug resistant pathogens. This will be achieved by exploiting the mechanisms that govern the growth of the outer membrane (OM) and a thin peptidoglycan (PG) layers and their coordination to highlight novel targets for antimicrobial discovery.I will research on scientific and non-scientific aspects related to the drug discovery process, including the following: • Dissecting at the molecular level the function of the core envelope machineries, i.e. Lpt and BAM complexes • Investigating how the activities of envelope machineries are orchestrated and coordinated with PG synthetic machineries elongasome and divisome to ensure appropriate growth of the envelope layers during the cell cycle • Developing innovative screening strategies/ technologies to identify molecules inhibiting envelope biogenesisActually, my project will be oriented on the study of the assembly and dynamics of the outer membrane protein inserting BAM machinery and its coordination with peptidoglycan (PG) synthetic machineries.

Cell Biology and Neuroscience LaboratoryThesis "Replicative incapability in terminally differentiated cells: Molecular Bases "

Laboratory of Astrobiology and Molecular Biology of Cyanobacteria from Extreme EnvironmentsThesis "Assessment of damages induced by space vacuum in a extremophile cyanobacteria, in preparation for the EXPOSE-R2 mission to the International Space Station"