Synthesis of novel DDR2 and casein kinase inhibitors.

Extensive knowledge of medicinal and synthetic organic chemistry deployed for multi-step chemical manipulation of complex steroid and heterocyclic molecules.Skilled in the execution of (anhydrous) reactions at a range of scales (<5 mg to 500g) and the handling of high-risk chemical reagents.Competent in structural elucidation of complex organic structures using 2D NMR techniques. Proficient in aseptic technique, PC2 protocol and development of complex cellular… Show more Extensive knowledge of medicinal and synthetic organic chemistry deployed for multi-step chemical manipulation of complex steroid and heterocyclic molecules.Skilled in the execution of (anhydrous) reactions at a range of scales (<5 mg to 500g) and the handling of high-risk chemical reagents.Competent in structural elucidation of complex organic structures using 2D NMR techniques. Proficient in aseptic technique, PC2 protocol and development of complex cellular bioassays.Skilled in the analysis and purification of complex stereoisomers, including use of HPLC, normal and reversed phase (manual and automated) chromatography and crystallisation. Experience in analytical, inorganic, physical and biological chemistry. Show less