Understanding the molecular mechanisms leading to a change in the location of a nuclear protein and its involvement in tumorigenesis, as well as its potential use as a therapeutic target

Assessing the impact of post-transcriptional modifications and tumorigenesis on ribosome export through the nuclear pore complex

Lymphocyte typing by FACS to assess lymphocyte subpopulations in contexts such as HIV therapy efficiency monitoring, CAR-T cells therapy, leukemias, lymphomas, grafts.

Characterization of externalized vimentin expression in head and neck cancer cell lines; Evaluation of the effect of specific antibodies on tumor growth in vitro

Judith Campisi's Lab:Senescence and SASP studies on fibroblasts; Characterization of a new biomarker for senolysis and its involvement in intracellular signaling; Discovery and evaluation of the senolytic potential of different molecules;Cell culture, proliferation assay, dose response assay, Western Blot, BCA assay, qPCR, SA beta gal staining, Immunofluorescence

Lymphocyte typing by FACS to assess lymphocyte subpopulations in contexts such as HIV therapy efficiency monitoring, CAR-T cells therapy, leukemias, lymphomas, grafts.

RNA extraction, comparative transcriptomics using Nanostring Technology on trophoblastic tumors to identify possible explanations for the differences regarding the response to chemotherapy

Routine biochemistry analyses on automaton

Home lessons of mathematics, physics and chemistry, biology, mid school level

Ultracentrifugation, liquid fraction separation and dosage to investigate dyslipidemiasGlycated hemoglobin dosage by HPLC

Dosages using automatons after preanalytic treatment if necessary, on blood, urines, amniotic liquid and other fluids; polyacrylamide gel electrophoresis ; quantitative and qualitative cytology ; blood and other fluids smear and staining; Reagents and consumables supply management

Private lessons of mathematics, mid school level