A part of the local Internal Applications Team responsible for building, programming, and testing fully integrated robotic work cells for clients using Green Button Go Scheduler, Orchestrator, and other solutions from Biosero's suite of software. Oversee the process from concept through to factory acceptance and site acceptance tests.-Assist in supporting customers/clients local to San Diego.-Cross functionally work with Pre-sales team to deliver solutions to many large and small biotech clients, the Integrations team to physically build out a workcell, and the field applications team to deploy and deliver the final delivery unit, on site.-Work in a client-facing position to ensure clear lines of communication and successful delivery of expected lab automation solutions-Serve at a subject matter expert on delivering lab automation solutions to clients not well-versed in lab automation tools/solutions.-Experience in deploying large scale end-to-end automation solutions with Biosero's Orchestration Suite-Experience in deploying automated mobile robots (AMRs)-Experience in scripting languages C#, Javascript, and Python for use within lab automation setting.

Specialize in technical aspects, programming, and building of automated laboratory workflows vital the company’s business model. Build, expand, and maintain hardware and software involved in site-wide laboratory automation. Work closely with all scientific departments in providing automated solutions to bench scientists. Act as Subject Matter Expert in automation equipment and downstream purification. Maintain a highly competitive and innovative high-throughput lab automation lab.Relevant work experience:Beckman Biomek iSeries (i5/i7)/Biomek 5Tecan Freedom Evo/EvoWareGreen Button Go Scheduling SoftwareProgramming in C/C++/C#, Javascript, Python3D Printing, FDM and SLS, Fusion 360, Solidworks

Responsible for discovery and early-stage development of downstream purification processes. Performance of down-scaled protein purification to optimize downstream operations at bench top AKTA scale. Performance of consistency runs at difference scales, benchtop AKTA Pure/Avant, to AKTA Pilot and AKTA Bioprocess/Ready. Development/optimization of protein purification processes ranging from midstream harvest of bacterial lysates, column chromatography (affinity, CEX, AEX, HIC, Mixed-mode), UFDF/TFF and final formulation. Responsible for consistent 5S of laboratory space to maintain productivity. Involved in company-wide Activities Committee to build and maintain company culture.Accomplishments:- Successful filing of NDA and drug approval, (teriparatide injection, generic of Forteo)- Brought a product package far enough for IND filing- Developed early stage HTP platform purification process for Drug Discovery

Temp-to-hire contract in Downstream Development. Responsible for assisting late-stage process characterization. Design and performance of DOE studies required for filing NDA with the FDA. Writing development reports to be filed with NDA package. Make sure processes and procedures are FDA audit ready. Responsible for consistent 5S organization of lab space.

Project lead for the downstream research and development and the GMP production of several clientele’s biologics. Manage a small group of lab technicians in experiments from laboratory scale all the way to production scale. Specialize in production of material for TOX , Viral Clearance Validation, IND, and Phase I Clinical Studies. Proficient in programming FPLCs for hands-off automated purification of biologics (AKTA Avant, AKTA Pilot, AKTA Ready). Specialize in protein chemistry and bioconjugation. Attend regular meetings with clients and provide project status updates in a timely fashion. Manage, procure, and train team members on new laboratory equipment. Implement new technologies for faster and more efficient bioprocessing. Write and modify SOPs for GMP compliance.Relevent Skills:• Aseptic and sterile technique, biosafety cabinet (BSC) work• Agilent HPLC, SEC-HPLC• FPLC (GE AKTA Avant/Pilot/Ready, Bio-Rad NGC)• Size exclusion (SEC), HIC, affinity, ion exchange chromatography• Viral Filtration using Millipore, Sartorius, or Pall filters• Harvest and Clarification of tissue cultures• Ultrafiltration/diafiltration (UF/DF), Tangential Flow Filtration (TFF)• SDS-PAGE, Agarose Electrophoresis, IEF, CE-SDS, cIEF• Flow cytometry (FACS)• UV/Vis spectroscopy, Beers law• Fluorometry• Bioconjugation, protein labeling techniques, protein engineering• ELISA/immunoassays• Microsoft Word, Excel and Excel Macros (Visual basic programming)• Programming in C and Arduino. Experience with Arduino and circuit boards.• Buffer prep• Good Documentation Practices, Good Manufacturing Practices (GDP/GMP)• Familiar with ISO 9001 environment

Responsible for managing a group of four scientists and assigning work to meet the needs and goals of the R&D team on time. Develop new technologies and applications for the company's core reagent business. Involved in the manufacturing, optimization, and preparation of new product inventory for release to public for use in DX setting, flow cytometry, immunohistochemistry, and biomedical immunoassays. Assist with the transfer of new products to manufacturing. Help write and revise SOPs and batch records for transfer to manufacturing department. Assist the Customs group with technical expertise. GMP and GDP trained under ISO9001. Correspond and assist scientists with their flow, IHC, or immunoassay experiments.Achievements include: • Releasing hundreds of new products to market • Successful launch of PE-eFluor610 color format • Increasing productivity by optimizing reactions • Increasing productivity by optimizing data recording and sample submitting procedures

Responsible for independently conjugating dyes to antibodies under SOP guidelines, writing and updating SOPs, ordering lab supplies. Involved in fragmentation and conjugation of antibodies as well as some process chemistry.Accomplishments include:• Implementing a high-throughput method of manufacturing• Streamlining documentation process by automating data collection in Excel with Visual Basic

Responsible for editing, adding, deleting, and combining entries within the Transportation Classification Database (TCDB) on http://www.tcdb.org/. TCDB is a database of membrane transport proteins run by Dr. Milton Saier's Bioinformatic's Group. New entries needed to be added as well as old entries changed or deleted as inconsistencies were found within the database. Spent a small amount of time doing some bioinformatics research involving homology the CRAC and ORAI1. Learned to work with BLAST alignments, ClustalX, and did some research on HMMR alignment programs.Accomplishments include:• Finding bugs in the TCDB system• Finding and fixing mistyped entries in TCDB• Adding and/or editing new entries into TCDB

Assisted with projects involving adult mesenchymal stem cells and differentiation of endothelial cells. Silinized glass microscope slides to chemically bind polyacrylamide gels to the surfaces of the glass for cell culture. Projects consisted of setting up chemical and physical environments for cell culturing in order to push towards the differentiation of endothelial cells. Some work with MATLAB in tracking particle movement within cells.Accomplishments include:• Fine tuning and optimizing the process of etching and silinizing glass.• In collaboration with a colleague, found optimal procedure to stamp samples of proteins in rows on gels on the nano-level.