Els Van Mierlo Email & Phone Number

Den Haag, Zuid-Holland, Nederland

Leiden, Zuid-Holland, Nederland

Leiden, South Holland, Netherlands

Leading own research project in the ‘Front Of The Eye’ team. Goal is to design and test an antisense oligonucleotide for the possible treatment of inherited ocular diseases. is investigated.- Designing and coordinating in-vitro and in-vivo experiments- Responsible for execution and data analysis of a research project- Communication with departments to ensure the progress of the research project - Contributed writing to two successful patent applications- Reporting and… Show more Leading own research project in the ‘Front Of The Eye’ team. Goal is to design and test an antisense oligonucleotide for the possible treatment of inherited ocular diseases. is investigated.- Designing and coordinating in-vitro and in-vivo experiments- Responsible for execution and data analysis of a research project- Communication with departments to ensure the progress of the research project - Contributed writing to two successful patent applications- Reporting and presenting of scientific results to team and supervisor (director)Used techniques: digital droplet PCR, qPCR, Bioanalyzer, Human cell culture Show less

Leiden, Provincie Zuid-Holland, Nederland

Within the ‘Black Box’ team involved in projects where antisense oligonucleotide therapies were developed and researched at cellular level for therapeutic purposes. Responsible for setting up a technology to identify proteins bound to an mRNA of interest in the ‘Mode of Action’ team.- Designing and running a research project with guidance- Finding solutions when the execution of a research experiment is in danger- Providing data for patent applications- Reporting and presenting… Show more Within the ‘Black Box’ team involved in projects where antisense oligonucleotide therapies were developed and researched at cellular level for therapeutic purposes. Responsible for setting up a technology to identify proteins bound to an mRNA of interest in the ‘Mode of Action’ team.- Designing and running a research project with guidance- Finding solutions when the execution of a research experiment is in danger- Providing data for patent applications- Reporting and presenting of scientific results to team and supervisor (scientist)Used techniques: digital droplet PCR, Western Blotting, Pull down assays Show less

Mainly researcher in the 'Mode of Action' team where the molecular mechanism leading to a biological functional effect of a lead compound is investigated.- Devising experiments under the supervision of a scientist- Performing experiments independently- Critically analyze results- Documentation of experimentsUsed techniques: Next Generation Sequencing, Fluorescence Microscopy

Leiden

Teaching second year students how to work sterile and secure. Overseeing the lab and helping students to carry out their experiments. Grading of reports and working attitude.

Leiden

Research Internship at the Molecular Genetics Group at University Leiden on the subject: Function and localization of Fam96A and Fam96B. Fluorescence microscopy, IFA staining and Hoechst-3342 staining were used to analyse the cellular localization of both proteins during mitosis and to analyse cell death and mitotic tubulin structures upon Fam96A and Fam96B transfection in human cancer cell lines.

Leiden

Research internship at the Molecular Biotechnology group at the Leiden University on the subject: the design of a bimolecular fluorescence complementation assay. Several bacterial cloning techniques were used to create sets of plasmids which can be used for bimolecular fluorescence complementation assays.

Master Of Science (Msc), Life, Science & Technology, Graduated 'Cum Laude' (Average Above 8.5 Out Of 10)

Activities and Societies: Study Association LIFE I did a one year Master Research Internship at the Molecular Genetics Group at University.

Bachelor Of Science (Bsc), Life, Science & Technology, Graduated 'Cum Laude' (Average 8,5 Out Of 10)

Activities and Societies: Study Association LIFE, First years commitee at Study Association LIFE (2008 t/m 2009) I did my Bachelor.

Atheneum, N&T And N&G, Average 7,6 Out Of 10

Activities and Societies: Mentor student (assisting a mentor of a first year) I graduated in the profiles Nature & Technics and Nature &.