Emily Jackson-Holmes Email & Phone Number

Carlsbad, California, United States

Viral Delivery for Cell and Gene Therapy

Lifecycle management and new product development for the viral vector production portfolio, with a focus on AAV production

Carlsbad, California, United States

Viral vector production

Greater Atlanta Area

Co-founded a 501c3 non-profit organization that creates science camps to expose middle school students. to biomedical STEM topics and encourage interest in related careers. As an organization, taught 500+ students in 9 states, trained 60+ graduate student instructors, and partnered with 4+ organizations.Developed original curriculum and hands-on activities in biomedical STEM subjects.Established relationships with Atlanta-area teachers and organizations to promote camps.Managed recruitment, interviewing, and training of graduate and undergraduate student teachers.Collaborated on advertising and marketing efforts to acquire customers.

Greater Atlanta Area

Developed a microfluidic platform for studying CAR-T cell and tumor cell interactions.Led a 4-person team that wrote and received a $50K grant from the National Science Foundation Innovation Corps (I-Corps) program to evaluate the commercialization potential of a platform for assessing CAR-T cell function. Performed 128 industry customer and KOL interviews to assess unmet needs, assess product-market fit, and develop a business model.Engineered a bioreactor for long-term culture and imaging-based analysis of forebrain organoids. Collaborated with two labs to: (1) study forebrain organoid development; (2) study the role of microglia in neurodevelopmental disorders.

Atlanta, Ga

Advisors: Dr. Hang Lu and Dr. Todd McDevittDeveloped a microfluidic device for culture and phenotypic analysis of stem cell aggregates. Studied how microfluidic culture conditions modulate progenitor motor neuron differentiation of mESCs. Resulted in two publications.Developed a bioreactor for long-term culture and imaging-based analysis of forebrain organoids. Resulted in one patent application and one in-preparation publication.Managed 3 multidisciplinary and multi-university collaborative projects. Facilitated communication between labs, led meetings, set project goals and deadlines, and communicated project updates to funding bodies.

Advisor: Dr. Klavs Jensen• Performed experiments to study the mechanism of a novel microfluidic intracellular delivery system and inform system design changes• Characterized mechanism of intracellular delivery in established mammalian and primary cell lines

Dortmund, Germany

• Developed a microfluidic device for compartmentalized neuronal (co)-cultures• Improved protocols for in situ biomolecule patterning of the device• Proposed and tested a new design feature that improved cell loading and positioning in the device

• Collaborated with a team to improve performance of a continuous glucose monitoring system• Optimized a quantitative chemical assay from literature in order to measure concentrations of chemicals coated on the sensor components • Collaborated with a manufacturing team who used the assay to standardize the system coating process

Advisor: Dr. Narendra Maheshri• Engineered a system in which to study dynamics of gene transcription in Saccharomyces cerevisiae, specifically by precise temporal control of transcription factor activity• Created a synthetic, chimeric Pho4p transcription factor with a tetR DNA binding domain that bound only the target reporter and could be activated and deactivated quickly, allowing for dynamic studies of the system

• Collaborated with a team to improve performance of a continuous glucose monitoring system• Performed in vitro and in vivo experiments (in a porcine model) to analyze and improve system design and function• Proposed alternative anticoagulation methods for the system, resulting in a patent application

Doctor Of Philosophy - Phd, Chemical And Biomolecular Engineering

Activities and Societies: Association of Chemical Engineering Graduation Students (AChEGS); K-12 STEM outreach.

Bachelor Of Science (B.S.), Chemical Biological Engineering

Activities and Societies: Undergraduate Research Opportunities Program; MIT Wind Ensemble; Emerson Scholarship Program for private music.