Roles include: Downstream Data capture, recording, analysis and presentation of dataLeading on Downstream/Quantum QCD/FRMs Liasing with Terumo team to ensure Quantum functionality & optimisationImproving/maintaining yield with GMP solutions Leading on SOP/QCD/FRM for Upstream Processing changesTech Transfer to GMP manufacturing team

Involved in the process development team Orbsen Therapeutics. As well as expansive cell culture knowledge, my other roles include primary processing of human tissues in isolating, manufacturing and scale up of the ORBCEL™ product. This characterization involves differentiation assays, ELISAs, Mycoplasma testing, flow cytometry and lymphocyte proliferation assays. The process development team collaborates with Teurmo Quantum® which is an automated cell culture system to facilitate the large scale manufacture of ORBCEL™. Ongoing work includes optimizing the Standard Operating Procedure for Quantum expanded ORBCEL™ which will be tech transferred to UK partners when complete.The process development team also collaborates with Miltenyi Biotec in developing the MACSQuant Tyto Cell Sorter for ORBCEL™ -based therapeutic applications. Previous projects within Orbsen Therapeutics:Deputy Manager of the junior scientists involved in the development of ORBCEL-EV™. ORBCEL-EV™ are Extracellular Vesicles isolated from ORBCEL™ products. This job involved developing and optimizing the Current Standard Operating procedure for ORBCEL-EV™ and transferring the protocol to the junior scientists within Orbsen Therapeutics.Previous work included the FP7-funded project, MERLIN, which focuses on using highly purified ORBCEL™ as a therapy for liver disease. The MERLIN project investigated the molecular mechanisms of the ORBCEL™ in inflammatory diseases. I supplied the Merlin partners with technical support and ORBCEL™ product for the duration of the project..

Required placement as part of M.Sc in Regenerative Medicine course.The main focus of this placement was to test a number of pharmacological compounds for their effects on a specific component in mesenchymal stem cells isolated from human bone marrow.Main techniques learned while on placement included: Cell culture, QPCR, ELISA, RNA isolation, Western Blotting

Main roles included assisting lessons. One on one tuition with customers.Stable management: Grooming, feeding and exercising horses and ponies.Volunteering in the Special Olympics Equestrian Club