Emmanuel Vial Email & Phone Number

Zug, Ch

• Programs- Preclinical programs (Lead to IND submission)- Early and late-stage development programs (phase 1-3)• Main Missions- Lead cross functional teams of experts (Clinical, Regulatory, CMC, Medical Affairs, Marketing & Commercial)- Establish program strategy and long-term vision- Ensure program execution within timelines, budget and expected quality through alignment of global functions- Represent the programs internally and externally• Main achievements- Completed IND packages for 2 topical programs in Atopic Dermatitis- Led the design of a late stage asset global clinical development plan in a LCM indication (FDA-endorsed)- Successfully initiated a phase 3 study

Zug, Ch

• Missions - Led and managed global biology & pharmacology department and activities- Discovery Project Leader • Main activities in biology department- Biologics discovery (generation & engineering)- HTS, in vitro pharmacology & in vivo pharmacology (small molecules and biologics)- Externally focused (100% via collaborations & outsourcing to CROs)- Scientific assessment of external opportunities• Main achievements- Successfully led the transition of pharmacology and biology activities to a fully virtual R&D environment

Zug, Ch

• Missions - Led the in vivo pharmacology department (20+ collaborators)- Discovery Project Leader• Main activities in the pharmacology department- Pharmacodynamy unit for target-based in vivo models and PK/PD- Immunology/Inflammation unit for disease-oriented in vivo models- Aesthetic & corrective unit for the evaluation of injectable fillers• Main achievements- Developed >30 in vivo efficacy and PK/PD models - Participated in the nomination of more than 10 clinical candidates

Suresnes, Île-De-France, Fr

• Lead the Pharmacology department (5 collaborators)• Discovery Project Leader (drug combination, Alzheimer disease)

Suresnes, Fr

• Lead the in vivo pharmacology department (8 collaborators)• Discovery Project Leader (monoclonal antibody targeting the tumor metabolism)

Paris, France, Fr

• Lead an in vivo pharmacology team (3 collaborators)

Paris, Fr

Dr. Jacques Pouysségur’s laboratory • Study of cancer invasion in vivo • 2 publications as last author

London, Greater London, Gb

Pr. Chris Marshall’s laboratory • Role of Ras and Rho small GTPases in cancer progression • 2 publications as first author

Doctor Of Philosophy - Phd, Biology

Master Of Science - Ms, Molecular And Cellular Biology

Bachelor Of Science - Bs, Biology, Chemistry