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The Clinton Health Access Initiative, Inc. (CHAI) is a global health organization committed to saving lives, reducing the burden of disease and strengthening integrated health systems in low- and middle-income countries where we work.More than 80 countries have access to CHAI-negotiated price reductions, vaccines, medical devices, and diagnostics. Current programs at CHAI include HIV/AIDS, Malaria, Tuberculosis, Hepatitis, Maternal, Newborn and Reproductive Health, Diarrhea and Pneumonia, Nutrition, Vaccines, Health Financing, Health Workforce, and Cancer.I joined CHAI in August 2020. For 24 years, I worked for GlaxoSmithKline, primarily in late phase inhaled product development and manufacturing. I led the CMC development, submission and approval of Advair HFA Inhalation Aerosol and a number of global products supporting life cycle maintenance of matured assets, such as Ventolin MDI. I am a colloid scientist by formal training and have been involved in a wide range of scientific and technical programs relating to understanding and controlling the behavior of particle-based products, including dry powders, liquid suspensions, emulsions and polymer solutions.In 2017, I took early retirement from GSK and started my own business providing experience-based consulting and educational services to clients involved in the development and manufacture of colloid-based products. Another aspect of my business drew upon a long track record in GSK of developing inexpensive analytical instruments to quantify critical quality attributes for which no existing methods were available. Most recently, I obtained a patent for measuring protein electrical charge in nanodispersions.My consulting experience has taught me skills I could not have learned in my earlier corporate position. It was fortuitous that I saw a post for my CHAI role and I realized the opportunity to use my experiences to help bring life saving medicines to those who lack the access that we take for granted.SKILLS• Complex project management including regulatory studies • Understanding and controlling robustness of pre- and post-market pharmaceutical products • Networking with internal and external partners • Deep interrogation and interpretation of complex datasets • Translating customer needs into tangible, measurable tasks • Creative problem solving, out-of-the-box thinking and innovation • Excellent technical and business communication • Expert physical chemist (doctorate)
All Is Grace Community Partnership Initiative
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Founder And PresidentAll Is Grace Community Partnership Initiative Oct 2024 - PresentI founded All is Grace Community Partnership Initiative, a nonprofit dedicated to empowering vulnerable communities in Zambia through education, skills training, and trauma healing. I lead the organization in securing resources, setting strategic goals, and developing sustainable programs that address generational challenges and foster holistic community growth.Key Responsibilities:Strategic Vision and Leadership: Established the mission and long-term vision of All is Grace to support resilience and community development, creating impactful programs in education, vocational training, and trauma healing.Fundraising and Financial Oversight: Drive fundraising efforts to sustain and expand initiatives, including grant applications and donor engagement. Manage budgets to ensure financial health as the organization pursues 501(c)(3) tax-exempt status.Program Development and Management: Oversee the All is Grace Community School and vocational training programs, which provide children with access to quality education and equip adults with skills for economic independence.Community and Stakeholder Engagement: Build partnerships with local leaders, stakeholders, and donors. Stay connected to the Zambian community to align programs with their evolving needs.Compliance and Administration: Handle nonprofit formation, legal compliance, and responsible fund management in both the U.S. and Zambia.Impact Communication: Share All is Grace’s story through digital platforms, presentations, and donor communications to engage and grow our supporter base.All is Grace’s mission is deeply personal, built on a commitment to provide opportunities for learning, healing, and resilience. Through this work, we aim to create a foundation for generational growth and lasting positive change. -
Product Development Senior Technical ManagerClinton Health Access Initiative, Inc. Aug 2020 - PresentBoston, Ma, UsCHAI is working with manufacturers of drug products to expand the product pipeline of low cost, high quality products. CHAI is also working with high-volume, early-adopter countries to overcome barriers that prevent adoption and scale-up, including regulatory hurdles and limited guidance on quality to build a healthy, competitive global market for these products, while negotiating with manufacturers to lower prices.I work across CHAI teams to develop strategies for overcoming key barriers related to product development, filing, approval, introduction and adoption. I am responsible for translating these strategies into actionable items, and managing relationships with manufacturers, partners, SRAs, NDRAs, Ministries of Health and other key stakeholders. -
OwnerEnlighten Scientific Llc Jan 2017 - PresentOwner of independent technical and scientific consultancy with expertise in colloid science, product development and manufacture, instrumentation, and experimental design and data analysis.https://enlightenscientific.com -
Global Product LeadGsk May 2016 - Mar 2017Brentford, Middlesex, Gb -
Acting Senior Scientific InvestigatorGsk Aug 2015 - May 2016Brentford, Middlesex, Gb• Key technical contributor to root cause investigation into major incidences of release testing OOS for key GSK inhaled asset that greatly threatened the ability of the company to meet market demand. Identified signification differences between device components that had not been identified previously. Shared findings and provided recommendations to GSK and external supplier technical teams. Provided clarity of my work and emphasized importance to incorporate some or all of my recommendations into ongoing investigations.• Co-developed and executed protocol to investigate sporadic OOS results for stability samples tested using an automated sample collection platform.• Contributed to the successful development and transfer (to manufacturing organization) of a more robust automated testing platform for an MDI asset. Created experimental design to determine the robustness of the method.• Recommended and led QFD-type process for device component redevelopment team in order to assist team and statisticians create a robust and efficient experimental design. • Contributed to oral suspension technical risk assessment in capacity as expert colloid scientist. -
Senior Scientific InvestigatorGsk Sep 2013 - Aug 2015Brentford, Middlesex, Gb• Global Process Robustness for key company inhaled asset core team member• Developed a robust manual dosing method for an MDI fitted with novel valve• Technical expert for global analytical team• Independent product expert for topical gel materials risk analysis• Product expert for topic gel deep dive diagnostic -
Senior Scientific InvestigatorGsk Nov 2010 - Sep 2013Brentford, Middlesex, Gb• Technical expert support for manufacturer of major GSK inhaled assets• Developed method to measure charge of spray impacting cascade impactor throat and showed choice of device components and formulation have significant effect.• Conceived, built and deployed rotary powder flow analyzer to aid definition of design space for pilot scale blending and dosating. Technique requires ~1g sample as compared to 25g or more for COTS equipment. Cost approx. $5K. Demonstrated that order of premixing can significantly affect blend uniformity. Presented at AIChE General Meeting in 2012.• Departmental Lead, dual combination SAR and PAR intranasal spray• Developed Monte Carlo simulation for particle ripening. Showed that laser diffraction analysis of acicular particles can be deconvoluted for more reliable interpretation.• Developed and conducted scientific workflow stream survey to build detailed database of coverage of skills and expertise required to meet departmental objectives. -
ManagerGsk Sep 2002 - Nov 2010Brentford, Middlesex, Gb• Leadership Team Member, global MDI product development• Leader, ADVAIR HFA MDI PPD team• Leader, Inhaled Delivery Sciences (US)• Lead user of statistical and data mining tools. Champion for use of Design For Manufacture (DFM), PAT/SPA and SixSigma principles.• Independently devised a unique apparatus that allows the surface charge of micronized API in liquid HFA to be measured. Demonstrated correlation between conditioning history of micronized albuterol sulfate and the surface charge in response to changing water content of propellant. -
Research Investigator/InvestigatorGsk Jul 1997 - Sep 2002Brentford, Middlesex, Gb• Core team member of development program for next generation of inhaler platforms o Project Team Leader for novel propellant MDI o Participated in external focus groups• Project Team Leader for novel MDI formulation development program -
Senior ScientistGsk Jul 1995 - Jul 1997Brentford, Middlesex, Gb• Led candidate selection and formulation development for safety assessment for a novel surfactant for HFA MDIs• Led pilot plant manufacturing campaigns for novel metered dose inhaler products -
ScientistGsk Jan 1993 - Jul 1995Brentford, Middlesex, Gb• Led external collaboration and demonstrated PoC of novel aerosol generator used with aqueous suspensions of various micronized drugs• Sourced new instruments for characterizing HFA suspension behavior and spray dynamics. Showed link between suspension aggregation state and dose uniformity. -
Technical ConsultantBrookhaven Instruments Jan 1993 - Jun 1993Holtsville, Ny, UsProvided technical advice to commercialize the light scattering technique I developed for my doctoral research. The Brookhaven ZetaPALS was the first such commercial instrument available. Three other manufacturers have subsequently developed similar instruments based upon my work. -
Research AssistantTexas A&M University Apr 1991 - Dec 1992College Station, Tx, Us -
Postdoctoral ResearcherShell Sep 1990 - Mar 1991London, England, Gb -
Postdoctoral ResearcherExxon Chemical Sep 1990 - Mar 1991
John Miller Skills
John Miller Education Details
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University Of BristolColloid Chemistry (Role Of Electrostatic Charge In Non-Polar Dispersions)
Frequently Asked Questions about John Miller
What company does John Miller work for?
John Miller works for All Is Grace Community Partnership Initiative
What is John Miller's role at the current company?
John Miller's current role is Founder, All Is Grace Community Partnership Initiative, Inc.Senior Technical Manager at Clinton Health Access Initiative, Inc..
What is John Miller's email address?
John Miller's email address is jm****@****ess.org
What schools did John Miller attend?
John Miller attended University Of Bristol.
What skills is John Miller known for?
John Miller has skills like Pharmaceutical Industry, Gmp, Hplc, Drug Development, Fda, Validation, Design Of Experiments, Regulatory Affairs, Medical Devices, Analytical Chemistry, Project Management, Colloids.
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