Enrique Ramos Email & Phone Number

El Paso, Tx, Us

El Paso, Tx, Us

My research focuses on addressing health disparities, particularly in Hispanic populations. With extensive expertise in bioinformatics, computational biology, genomics, and other omics, I lead investigations aimed at uncovering the molecular mechanisms driving aggressive cancers like triple-negative breast cancer (TNBC).

El Paso, Texas, Us

Cancer GenomicsThe emphasis of my current research is on expression analysis of long non-coding RNAs (lncRNAs) in estrogen-regulated signaling and its application as novel biomarkers and potential therapeutic targets in different types of cancer. Additionally, I am engaged in the integration of multi-omics data for cancer and neurological diseases, along with working on single-cell technologies.Cancer Genomics Researcher - lncRNA & Estrogen-Regulated Signaling SpecialistFeb 2019Role: Postdoctoral Research AssociateInstitution: Texas Tech University Health Sciences Center El PasoSupervisor: Shrikanth S. Gadad, Ph.D. M.Sc. – Assistant Professor, CPRIT ScholarResponsibilities:1. Led cutting-edge research initiatives focused on the expression analysis of long non-coding RNAs (lncRNAs) in the realm of cancer genomics.2. Investigated the roles and mechanisms of lncRNAs in estrogen-regulated signaling pathways and their implications in various cancer types.3. Identified and characterized novel biomarkers through rigorous lncRNA studies to advance early cancer detection and prognosis.4. Explored the potential of lncRNAs as therapeutic targets, setting the stage for innovative cancer treatments.5. Collaborated with interdisciplinary teams, ensuring seamless integration of genomics data with oncological research.6. Kept abreast of latest advancements in genomics and cancer research, incorporating new findings and technologies into ongoing studies.7. Published research findings in reputable scientific journals and presented at national and international conferences to share knowledge and gather expert feedback.8. Engaged in grant writing and fundraising activities to secure resources for continued research advancements.9. Supervised and mentored summer, undergraduate and graduate students.

Jupiter, Fl, Us

Research focused on data-driven projects with a focus in health, and longevity incorporating epigenetics, multi-omics data analysis integration, single-cell transcriptomics, and gut-biome. Conduct cutting-edge research using predictive modeling and machine learning to enhance longevity and optimize health, as well as analyzing large-scale biomedical databases using computational strategies.Data Scientist & Biomedical Researcher - Health & Longevity FocusMay 2022 – Oct 2023Role: Senior Scientist of BioinformaticsCompany: VoLo Foundation – VoLo Health InitiativeSupervisor: Daniel Vera, Ph.D. – Director of Research for VoLo FoundationResponsibilities:1. Spearheaded research initiatives in health and longevity with a concentration on data-centric methodologies.2. Pioneered studies incorporating epigenetics, multi-omics data analysis, single-cell transcriptomics, and gut microbiome dynamics.3. Developed and applied predictive modeling and machine learning algorithms to enhance human longevity and optimize overall health outcomes.4. Managed the comprehensive analysis of large-scale biomedical databases through advanced computational strategies and techniques.5. Collaborated with interdisciplinary teams to ensure accuracy and applicability of findings in the broader scope of biomedical research.6. Regularly reviewed and integrated latest advancements in the field to stay abreast with state-of-the-art methodologies.7. Translated complex research findings into actionable insights for medical professionals and stakeholders.

Houston, Texas, Us

Pediatric cancer genomics/ Precision medicineGenomic characterization of rare pediatric central nervous system diseases: malignant epithelioid glioneuronal tumor (MEGNT) and pilocytic astrocytoma with anaplasia (PAA). The main goal of these studies was to describe clinical, pathologic, and molecular features using an integrated genomic approach that included exome, transcriptome, targeted mutation panel sequencing and copy number arrays.Pediatric Cancer Genomics Researcher - Precision Medicine SpecialistAug 2015 – Jun 2017Role: Postdoctoral Research AssociateInstitution: Baylor College of MedicineSupervisor: Donald Williams Parsons, M.D., Ph.D. – Professor, Department of PediatricsResponsibilities:1. Pioneered genomic research initiatives focusing on rare pediatric central nervous system diseases, notably malignant epithelioid glioneuronal tumor (MEGNT) and pilocytic astrocytoma with anaplasia (PAA).2. Conducted comprehensive genomic characterizations to understand the clinical, pathological, and molecular landscapes of these rare pediatric conditions.3. Employed an integrated genomic approach, utilizing a combination of exome sequencing, transcriptome analysis, targeted mutation panel sequencing, and copy number arrays.4. Aimed to provide a deeper insight into the etiology and progression of these diseases, with the intention of paving the way for more effective and personalized treatment options.5. Collaborated closely with clinicians, pathologists, and bioinformaticians to ensure a holistic understanding of findings and their potential implications.6. Disseminated research findings through scientific journals, conferences, and seminars to further the knowledge base and foster collaborations in the field.7. Championed the cause of precision medicine in pediatric oncology, advocating for personalized therapeutic strategies based on individual genomic profiles.8. Ensured compliance with ethical standards and guidelines when handling sensitive data.

St. Louis, Mo, Us

Genetics/ Genomics/ Bioinformaticscontributed to the development and application of high-throughput methodological and computational tools that enable efficient and accurate identification of genome-wide rare sequence and epigenetic variants. The application of these algorithms to clinical cases identified potential disease-causing genes in complex phenotypes: fatal extreme microcephaly, congenital animalities of kidney or lower urinary tract and pedigree-specific variants influencing longevity. The latter portion of my graduate studies focused on additional types of epigenetic variation (DNA methylation) and the influence in complex phenotypes and biological processes.Genetics & Bioinformatics Researcher - Genomic Variants SpecialistAug 2008 – May 2015Role: Graduate Student – Ph.D. Molecular Genetics and GenomicsInstitution: Washington University in St. LouisSupervisor: Todd E. Druley, M.D., Ph.D. – Associate Professor, Chief Medical Officer at Mission BioResponsibilities:1. Played a pivotal role in the development and application of high-throughput computational tools and methodologies tailored for efficient genome-wide detection of rare sequence and epigenetic variants.2. Demonstrated expertise in integrating bioinformatics with genetics and genomics to offer innovative solutions for complex biological problems.3. Applied developed algorithms to clinical cases, leading to the identification of potential disease-causing genes in intricate phenotypes, notably fatal extreme microcephaly and congenital anomalies of the kidney or lower urinary tract.4. Undertook in-depth research into pedigree-specific variants, shedding light on their potential influence on longevity.5. During the advanced stages of my graduate studies, expanded research scope to encompass varied epigenetic variations, with a keen emphasis on DNA methylation.6. Explored the consequential influence of epigenetic variations on intricate phenotypes and broader biological processes.

El Paso, Tx, Us

Genetics/ Chemotherapeutics/ ParasitologyI worked with the protozoan parasite Trypanosoma cruzi the pathological agent for Chagas’ disease. The focus of my work was to screen different novel compounds against the parasite in cell culture and mouse model. This research led to the successful identification of an effective low toxicity chemotherapeutic agent and determine the mechanism of action.Research Scientist - Chemotherapeutics & Parasitology SpecialistMay 2005 – May 2008Role: Undergraduate Research AssistantInstitution: The University of Texas at El PasoSupervisor: Rosa A. Maldonado, Ph.D. – Associate ProfessorResponsibilities:1. Led comprehensive research on the protozoan parasite Trypanosoma cruzi, the causative agent of Chagas’ disease, a major public health concern.2. Designed and executed screening protocols to evaluate the efficacy of novel compounds against the parasite in both cell culture systems and mouse models.3. Successfully identified a promising low-toxicity chemotherapeutic agent with potent anti-Trypanosoma cruzi activity.4. Delved into the mechanistic study of the identified agent, elucidating its mode of action and potential therapeutic applications.5. Collaborated closely with a team of geneticists, chemists, and parasitologists to ensure rigorous evaluation and optimization of the identified compounds.6. Regularly updated stakeholders and fellow researchers on progress and findings, contributing to shared knowledge and collaborative advancements in the field.7. Ensured all research activities were compliant with ethical guidelines, maintaining the welfare of experimental animals and ensuring data integrity.8. Authored and contributed to scientific publications detailing the research findings, offering valuable insights for future chemotherapeutic developments in parasitology.9. Supervised and mentored undergraduate students.

Doctor Of Philosophy - Phd, Molecular Genetics And Genomics

Bachelor Of Science - Bs, Microbiology/ Chemistry