Eng Piew (Louis) Kok Email & Phone Number

Singapore

- Developing web-based application that utilizes large language models (LLM) to automate the generation of medical reports.- Developing a web-based application to help medical students practice and enhance their clinical skills through interactive learning and simulation tools.- Creating WhatsApp chat applications to help patients assess their health conditions and decide whether to visit a general practitioner or the emergency department.- Collaborating with clinical departments to identify, plan, and develop AI use cases, enhancing workflow efficiencies and diagnostic accuracy.- Leading Artificial intelligent (AI) use case development in close coordination with clinicians, ensuring alignment of AI-driven solutions with clinical needs and priorities.- Engaged in collaborative technical knowledge sharing across hospitals within the National University Health System.- Conducting training to internal staff on the use of Artificial intelligences and best practices in healthcare.

Singapore

- Designed and developed end-to-end bioinformatics analytic solutions for shotgun sequence analysis of metagenome, including taxonomic and functional annotation.- Built CI/CD pipelines for software development, automation, and deployment, enabling faster and more efficient development cycles.- Developed deep learning models for classification of microbiome data, achieving high accuracy in identifying microbial communities.- Conducted analysis of HIV molecular transmission networks and built analytic applications for HIV data analytics, providing insights into the epidemiology of HIV.- Analyzed SAR-CoV-2 WGS data for variation, clade, and lineage detection, contributing to our understanding of the evolution and spread of the virus.- Planned and designed qPCR panels for diagnostics of various infectious diseases, enabling rapid and accurate diagnosis of these diseases.- Collaborated with assay scientists to plan R&D experiments for the development of NGS-based molecular diagnostic kits, contributing to the development of innovative and effective diagnostic tools.- Provided expert bioinformatics support to stakeholders, including scientists, clinicians, and other healthcare professionals, ensuring that they have the information and tools they need to make informed decisions.

Singapore

- Designed and developed end-to-end bioinformatics analytic solutions for amplicon sequence analysis of clinical human microbiome, enabling rapid and accurate detection of medically important pathogens and antimicrobial resistant genes.- Established and curated microbial and antimicrobial gene databases, ensuring high-quality and up-to-date data for bioinformatics analysis.- Established and curated microbial and antimicrobial gene databases, ensuring high-quality and up-to-date data for bioinformatics analysis.- Built CI/CD pipelines for software development, automation, and deployment, enabling more efficient and effective development cycles.- Conducted computational analysis of SAR-CoV-2 WGS data for clade and lineage detection, contributing to our understanding of the evolution and spread of the virus.- Collaborated with assay scientists to plan R&D experiments for the development of NGS-based molecular diagnostic kits, contributing to the development of innovative and effective diagnostic tools.- Provided expert bioinformatics support to stakeholders, including scientists, clinicians, and other healthcare professionals, ensuring that they have the information and tools they need to make informed decisions.

Singapore

- Designed and implemented a deep learning-based method for the detection of modified bases from Oxford Nanopore direct RNA sequencing data, achieving high accuracy in identifying modifications.- Designed and implemented a bioinformatics workflow for detecting RNA editing events using Illumina data.- Performed MACS analysis of Illumina ChIP-Seq data.- Supervised undergraduate final year projects, providing guidance and support to students in their research and development.- Served as an instructor for Team:NTU-Singapore, iGEM 2018, teaching and mentoring students in synthetic biology and bioinformatics.

Kuala Lumpur, Malaysia

- Provided technical leadership and mentorship to junior scientists, overseeing their research and development activities and ensuring the timely and accurate completion of projects.- Designed and developed custom bioinformatics pipelines tailored to scientists' specific research needs, utilizing a range of computational tools and software to analyze Sanger and Next Generation Sequencing (NGS) data (including Illumina and Roche 454).- Planned and executed bioinformatics analyses to support research, diagnostics, and commercialization efforts in biotechnology and medicine, leveraging expertise in bioinformatics and genomics to deliver high-quality results.- Conducted bioinformatics training sessions for researchers and staff, developing and delivering content on the latest techniques and best practices in bioinformatics analysis to promote effective data-driven decision making.- Managed data center and HPCC facilities at the operational unit, including Linux administration, optimization of high-performance computing resources, and development and maintenance of bioinformatics pipelines to ensure reliable and reproducible results.

Kuala Lumpur, Malaysia

- Provided technical leadership and mentorship to junior scientists, overseeing their research and development activities and ensuring the timely and accurate completion of projects in diverse research areas such as metagenomics, bacterial genomics, fungal genomics, oil palm genomics, genotyping, and systems biology.- Developed bioinformatics pipelines tailored to the scientists’ requirements to process Sanger and Next Generation Sequencing (NGS) data, including Illumina and Roche 454 data, for research, diagnostics, and commercialization applications.- Implemented and optimized bioinformatics analyses for diverse projects, including the development of novel computational methods for genome assembly, annotation, and comparative genomics.- Provided bioinformatics training to researchers, developed and maintained Linux-based computing environments, and managed data center and high-performance computing (HPCC) facilities to support the scientific workflow and data analysis.

Kuala Lumpur, Malaysia

- Designed and implemented custom bioinformatics pipelines to analyze Sanger and Next Generation Sequencing (NGS) data, including Illumina and Roche 454 data, to support research efforts in microbial genomics, metagenomics, and systems biology.- Provided bioinformatics training to researchers, developed and maintained Linux-based computing environments, and managed data center and high-performance computing (HPCC) facilities to support the scientific workflow and data analysis.

Kuala Lumpur, Malaysia

- Provided support to senior researchers in the planning and implementation of research and development activities in microbiology, metagenomics, molecular biology, field experimental trials, and bioinformatics.- Conducted microbiological culture, DNA extraction, PCR and gel electrophoresis, molecular cloning, biochemical tests and basica bioinformatics analysis such as BLAST, phylogenetic tree construction and multiple sequence alignment in the laboratory.

Petaling Jaya, Selangor, Malaysia

- Conducted clinical laboratory diagnosis for patients and general health screening for walk-in clients.- Executed diagnostic tests such as ELISA, serology, bacterial culture and sensitivity tests, and identification of bacterial species through biochemical approaches.

Saskatoon, Saskatchewan, Canada

- Provided assistance in the research on bioherbicides by developing a liquid fermentation system to improve the growth and bioherbicidal properties of Phoma macrostoma, a bio-control fungus, for effective weed control of common dandelion (Taraxacum officinale).

Winnipeg, Manitoba, Canada

- Conducted research on the effect of Hepatitis C Virus (HCV) proteins on cytokine stimulation, specifically IL-10 and IFN-γ, in Human Peripheral Blood Mononuclear Cells (PBMC).

Master Of Bioinformatics (With Distinction), Systems Biology And Mathematical Modeling

Research Title: Peculiar feed forward loop network motifs in Escherichia coli Research Summary: To investigate the role and significance.

Bachelor Of Science (B.Sc.), Microbiology, General