Eric Grazzini Email & Phone Number

Castanet-Tolosan, Fr

Seattle, Wa, Us

• Management and coordination of biosimilar projects with global CMC organization• Lead the implementation of Toulouse biosimilar development program

Hamburg, De

Montreal, Quebec, Ca

Montreal, Quebec, Ca

Ottawa, Ontario, Ca

Ottawa, Ontario, Ca

  Coordinated collaboration with Montreal investors and partners Delivered realistic budget plans and strategic perspectives Implemented strategy and led GPCR positive allosteric modulator projects  Initiated interaction with clients (pharmaceuticals and academic labs)

Cambridge, Cambridgeshire, Gb

 Led all biology (including experimental design), pharmacology, toxicology, Pharmacokinetic-Pharmacodynamic and biomarker identification activities related to small molecules candidate drug projects (up to clinical Phase II) Coordinated patent redaction in collaboration with AstraZeneca lawyers  Organized collaboration with other AstraZeneca therapeutic areas and external partner (CROs). Accelerated progression of Lead optimization project up to candidate drug nomination and phase I study. Successfully implemented and coordinated collaborations with MedImmune on two antibody drug discovery projects (pain and inflammation)  Implemented fruitful collaborations with key opinion leaders from McGill University, Montreal Neurological Institute, University of Montreal, Indiana University School of Medicine and Sherbrooke University Led the global CNS/Pain/inflammation “Target Validation Network” and in collaboration with other leaders delivered recommendations for improvement to all AstraZeneca therapeutic areas

Cambridge, Cambridgeshire, Gb

 Coordinated and managed two successful projects that transitioned to the next milestone (Investigational New Drug (IND) and lead generation). Project documents became a benchmark for the therapeutic area Coached and managed successfully a group of two Ph.D and four master scientists. Established clear challenging but achievable goals with section's input. Led the implementation of native cell assays and systematic label free technology utilization.

Cambridge, Cambridgeshire, Gb

 Headed a team of three Ph.D and four masters. Hired one master scientist. Participated to Molecular Science department re-organization.  Championed and provided strategic analysis of a new analgesia target that obtained best ranking. Designed and led successfully High Throughput Screening Campaign.

Cambridge, Cambridgeshire, Gb

 Proposed and led one new analgesia project that progressed from target validation to lead identification  As core team member, Molecular Science/pharmacology representative coordinated all the in-vitro assays related to one LO project and accelerated the transition to candidate drug (CD) nomination

Cambridge, Cambridgeshire, Gb

 Efficiently managed a team composed of four Ph.D and three masters Led the implementation of two ligand gated ion channels projects As core team member, provided pharmacology and molecular biology expertise to one LO project

Cambridge, Cambridgeshire, Gb

 Co-responsible of the establishment and the development of the Ligand Identification for orphan G Protein Coupled Receptors (GPCRs). Received the AstraZeneca R&D Global Scientific and Technical Achievement Award for the deorphanisation of 6 orphan GPCRs that produced four new projects in two different therapeutic areas, coordinated patent redaction in collaboration with AstraZeneca lawyers

Barrie, Ontario, Ca

Oxytocin and vasopressin receptors regulation

Doctor Of Philosophy (Ph.D.), Pharmacology, Biochemistry And Molecular Biology

Master'S Degree, Health And Biology