Eric Chatelain Email & Phone Number

Geneva, Ch

- Leader of the Translational Drug development platform building for COVID-19 (in vitro, ex vivo, in vivo models, PK modelling, PKPD relationships assessment): Generation of preclinical evidence in support of treatment arms of clinical trial- Joint-Leadership of DNDi entire Discovery/Lead Optimization effort- Responsible for the team that delivered pre-clinical candidates for Visceral Leishmaniasis (VL) as well as for their entire further preclinical development (regulatory IND-enabling studies)- Leadership role in translational research: Improve predictability of in vivo animal disease models, candidate compound PK/PD analysis and biomarkers identification and validation - Leader of DNDi Chagas Biomarkers strategy and its implementation- Definition with the Head of Clinical Program of the overall public health research strategy for Chagas disease at DNDi - Management and supervision of global project teams with partners from academia, pharmaceutical and biotechnology companies and contract research organizations

Geneva, Ch

- Responsible for all activities in Chagas disease portfolio, from discovery to clinical candidate nomination- Led the multinational team that delivered pre-clinical candidates for Chagas disease- Definition with the Head of Clinical Program of the overall public health research strategy for Chagas disease at DNDi

Geneva, Ch

- Responsible for all screening/early discovery activities for new drugs for neglected diseases (Human African Trypanosomiasis, Leishmaniasis, Chagas) in DNDi portfolio- Development and implementation of DNDi discovery strategy: transition from a project-based to a more strategic-oriented approach (portfolio) of DNDi screening/discovery activities; HTS in place for all 3 kinetoplastids, increased access to pharmaceutical compound libraries and strengthened ties with other Product Development Partnerships (GATB, MMV,DDU) and partners - Responsible for the development and application of High-Troughput/High-Content Screening assays with Insitut Pasteur Korea -for two parasites involved in DNDi core diseases- that significantly enhanced DNDi's capacity to consolidate its discovery pipeline and implement its discovery strategy

- Responsible for all preclinical research activities including the budgeting, planning and coordination with the other R&D departments and CROs, documentation and control- Active member of the R&D and Scientific Advisory Boards, acquainted with all processes, workflows and interfaces involved in project development and interacting with people of all disciplines at all levels- Involved in Innovation Management and Business Development activities with Head R&D: Work out ideas and proposals, develop concepts for new projects/products fitting with the company strategy; Evaluation –including Due Diligence- of possible collaborations opportunities with external partners such as university, industry/biotech and CRO and presentation to the company board- Biosafety Officer: Set-up and implementation of the company’s biosafety concept

- Planning, budgeting and set-up of two new laboratories. Set-up and use of new methods and models for formulation tolerance and efficacy assessment and topical delivery systems screening purposes- Participation together with Novartis, Pfizer, GSK and 3M at inter-laboratory pre-validation studies for the evaluation of the SkinEthic model as possible tool to assess the local tolerance of topical products

Basel, Bs, Ch

Gene therapy project: Generation of adenoviral constructs as carriers for molecular radiosensitisers under the control of tumor specific promoters. Goal: Increase the radiosensitivity of tumor cells.

London, Gb

Investigation of the role of mouse Fibroblast Growth Factor 3 using genetic strategies (specific and conditional knock-out of the fgf3 gene in the mouse involving the Cre-LoxP technology). Structure/function analysis of its specific receptors.

Diploma In Management Studies (Dms), Business Administration And Management, General

Doctor Of Philosophy (Ph.D.), Biochemistry And Molecular Biology

Diplôme D’Etudes Approfondies (D.E.A.), Biochemistry

Master'S Degree, Animal Physiology And Biochemistry