Erich Koller Email and Phone Number
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Erich Koller is a Senior Principal Scientist at F. Hoffmann-La Roche Ltd at Roche. They possess expertise in biotechnology, drug discovery, sequencing, lifesciences, in vitro and 45 more skills. They is proficient in French and Italian. Colleagues describe them as "Erich is a thorough investigator and an excellent scientist. He reported to me while I worked at Isis Pharmaceuticals. He has extensive knowledge of oncology pathways, particularly the cell cycle and apoptosis. His outstanding cell and molecular biology skills allowed him to make good progress on his projects. I know that since I left Isis he has also done excellent work to help begin to elucidate the mechanisms of antisense oligonucleotide uptake. Erich has a strong work ethic, good interpersonal skills and a driving scientific curiosity which makes him an effective worker either individually or as part of a team."
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Senior Principal ScientistF. Hoffmann-La Roche Ltd Jul 2020 - PresentBasel, Switzerland
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Pdm (Pharmacokinetics, Dynamics And Metabolism) Project Leader In Roche Innovation Center BaselRoche Jun 2016 - PresentBasel Area, Switzerland -
Principal Scientist Pharmaceutical SciencesRoche Feb 2014 - PresentBasel, Switzerland
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Assistant DirectorIonis Pharmaceuticals, Inc. May 2002 - Dec 2013• Characterized mechanisms of ASO uptake into cells and tissue. Identified several genes that are involved in ASO uptake into cells.• Led Kinase project with collaborate partner • Conducted preclinical studies with Eg5 inhibitor for cancer.• Conducted preclinical studies with Stat3 inhibitor for cancer.• Established a correlation between siRNA potency and ability to compete with other siRNAs.• Investigated the role of microRNA in cell cycle.• Supported Medicinal Chemistry project to increase in vivo activity of siRNA and PNA.• Screen small molecules using HCV-replicon assay -
Senior ScientistIonis Pharmaceuticals, Inc. Apr 1999 - Apr 2002Carlsbad, Ca• Led research collaboration with AstraZeneca for Cancer targets.• Led cancer project in GeneTrove, Functional Genomics Department
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Postdoctoral FellowIonis Pharmaceuticals, Inc. Apr 1997 - Apr 1999Carlsbad, Ca• Identified antisense oligonucleotides against TRAF2, TRAF6, NIK, IKKa, IKKb• Determined role of these proteins in JNK and NF-kB activation and apoptosis.• Identified mouse IKKb inhibitor. Characterized in vivo inhibition of mouse IKKb• Identified antisense oligonucleotides against G-alpha-i1, -i2 and i3• Characterized isotype specific role of Gai-isoforms in induction of cyclooxygenase-2 by LPA and IL-1b.
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Postdoctoral FellowSanford-Burnham Medical Research Institute Apr 1992 - Apr 1997La Jolla, CaStudy of cell-cell interactions by cadherins.• Established protein transport assay in epithelial cells.• Found that T-cadherin is transported directly to the apical surface and N-cadherin to the basolateral surface of MDCK cells.• Identified the T-cadherin carboxyl-terminal 76 amino acids containing the apical targeting signal as well as the signal for GPI-anchor attachment. • Constructed and purified an Ig-T-cadherin fusion protein.• Identified 45kD kinase that coprecipitates with T-cadherin. • Discovered an anoikis (apoptosis) resistant MDCK clone expressing a mutant N-cadherin.• Evaluate mechanism which leads to survival of mutant clone (an important process in tumorigenesis).
Erich Koller Skills
Erich Koller Education Details
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Biochemistry And Molecular Biology -
Biochemistry
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Gymnasium ImmenseeBaccalaureat
Frequently Asked Questions about Erich Koller
What company does Erich Koller work for?
Erich Koller works for Roche
What is Erich Koller's role at the current company?
Erich Koller's current role is Senior Principal Scientist at F. Hoffmann-La Roche Ltd.
What is Erich Koller's email address?
Erich Koller's email address is ek****@****sph.com
What is Erich Koller's direct phone number?
Erich Koller's direct phone number is +176060*****
What schools did Erich Koller attend?
Erich Koller attended Eidgenössische Technische Hochschule Zürich, Eth Zürich, Gymnasium Immensee.
What skills is Erich Koller known for?
Erich Koller has skills like Biotechnology, Drug Discovery, Sequencing, Lifesciences, In Vitro, Molecular Biology, In Vivo, Genomics, Biomarkers, Biochemistry, Qpcr, Cell Biology.
Who are Erich Koller's colleagues?
Erich Koller's colleagues are Akhona Ngcatshe, Dr. Mandy Merker, 稽智敏, András Tiszai, Evert-Jan Sneekes, Bartosz Garstka, Yingli Huang.
Not the Erich Koller you were looking for?
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1stadtluzern.ch -
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Erich Koller
Marketing Und Kommunikation, Digital Und Analog, Emba Smart Und Digital MarketingSt Gallen, Switzerland1diebotschafter.ch -
Erich Koller
What Do You Want Your Time Being Spent On? Shiny Reports Or Getting The Job Done?Zurich, Switzerland3hotmail.com, iagility.com, upc-cablecom.ch
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