Analytical characterization and method development of viral particles for gene therapy. Analytical techniques include nuclear magnetic resonance, analytical ultracentrifugation, fluorescence, transmission electron microscopy, dynamic light scattering, and circular dichroism.

Development of dynamic nuclear polarization nuclear magnetic resonance instrumentation and experiments. Utilization of these methods for biomolecular structure determination; currently for drug development of Protein Kinase C activators.

Design and construction of an NMR apparatus for CO2 capture and sequestration experiments: a high-pressure manifold for gas mixtures (to simulate flue gases) was constructed, in conjunction with a high-pressure, high-temperature NMR probe to examine a range of materials for carbon capture (i.e., polymers, zeolites and MOFs), and mineralization of CO2 in conditions to mimic geologic storage (i.e., minerals, rock samples). This probe can detect solid, liquid, gas, and supercritical phases of 13C for in situ NMR studies.

Optically Pumped NMR and Polarized Photoluminescence on Semiconductors: constructed a low-temperature optically-accessible NMR probe for studies combining laser excitation of semiconductors with NMR detection, and simultaneous detection of polarized photoluminescence from the sample. Gained experience with optical pathway design and setup, care and alignment of Class IV lasers, high voltage radio-frequency electronics, and cryogenic design. Measurements focused primarily on GaAs/AlGaAs quantum wells to determine spin physics of optical pumping, but measurement on bulk GaAs were performed.