Erik Van Den Berg Email & Phone Number

Den Haag, Zuid-Holland, Nederland

Den Haag, Zuid-Holland, Nederland

Rotterdam, Zuid-Holland, Nederland

Den Haag, Zuid-Holland, Nederland

Part of the team 'Translations', responsible for the timely validation of European Patents in The Netherlands.

Leiden

Internship title: The added value of FAIR data stewardship for discovering knowledge about human genetic diseasesIn this internship, the benefits as well as the efforts of making data FAIR have been described. This was achieved by:- Investigating the role of metabolism in Polycystic Kidney Disease- Using some of the data files to make them adhere more to the FAIR PrinciplesAlthough the results were inconclusive to make any statement regarding the role of metabolism in… Show more Internship title: The added value of FAIR data stewardship for discovering knowledge about human genetic diseasesIn this internship, the benefits as well as the efforts of making data FAIR have been described. This was achieved by:- Investigating the role of metabolism in Polycystic Kidney Disease- Using some of the data files to make them adhere more to the FAIR PrinciplesAlthough the results were inconclusive to make any statement regarding the role of metabolism in Polycystic Kidney Disease, the efforts of making data more FAIR were fairly successful. By rewriting the dataset into RDF (Resource Description Framework) language, the data has been made more FAIR, as it become more readable for machines and therefore, more findable. Show less

Leiden

Internship title: GPR120 deficiency increases fat mass and decreases brown adipose tissue activity in mice.During this internship, I assisted and performed research into the effects of GPR120 deficiency in high fat diet mice. GPR120 is a highly expressed receptor in white adipose tissue and brown adipose tissue, both of which play a large role in triglyceride metabolism. This internship focused on the effects of GPR120 deficiency on lipid metabolism. Many common lab techniques… Show more Internship title: GPR120 deficiency increases fat mass and decreases brown adipose tissue activity in mice.During this internship, I assisted and performed research into the effects of GPR120 deficiency in high fat diet mice. GPR120 is a highly expressed receptor in white adipose tissue and brown adipose tissue, both of which play a large role in triglyceride metabolism. This internship focused on the effects of GPR120 deficiency on lipid metabolism. Many common lab techniques were used during this internship, including:- RNA isolation- cDNA synthesis- qPCR- histologie- microscopy- Animal handling techniques (observed)- Common analysis techniques (SPSS analyses, Microsoft Excel, ImageJ)The overall results of the internship were that GPR120 deficiency .... Show less

Leiden

Internship title: Investigating the effects of ALK1 knockdown on muscle regeneration in dystrophic musclesThis project was a pilot study where we looked at the effects of an ALK1 knockdown in dystrophic mice muscles. This was done with an experimental antisense oligonucleotide that targeted ALK1 transcripts. Techniques that were used included:- RNA isolation- cDNA synthesis- qPCR- rtPCR- cell culture- light microscopy- immunofluoresent… Show more Internship title: Investigating the effects of ALK1 knockdown on muscle regeneration in dystrophic musclesThis project was a pilot study where we looked at the effects of an ALK1 knockdown in dystrophic mice muscles. This was done with an experimental antisense oligonucleotide that targeted ALK1 transcripts. Techniques that were used included:- RNA isolation- cDNA synthesis- qPCR- rtPCR- cell culture- light microscopy- immunofluoresent microscopyAdditionally, during this project, I tested a new software program that was used in the semi-automatic measuring of muscle fiber surface in immunofluoresent muscle cross-sections. I documented the use of the software program, and advised the research group on its use, its benefits and its limitations. Show less

Master Of Science - Ms, Biomedical Sciences, General

Bachelor Of Science (Bsc), Biomedische Wetenschappen (Biomedical Sciences)