Esen Karol's clients and collaborators have included Arter Space for Art, Istanbul Foundation for Culture and Arts, Mavi, Yapı Kredi Publications, Vehbi Koç Foundation, Radikal (Doğan Media Group), Meşher and SALT. She received her master’s degree in communications design from Pratt Institute, New York, where she was a Fulbright Fellow. Her works are in the collection of Art Institute Chicago and her posters are in the collection of Museum für Gestaltung, Zurich. Her current focus is on projects relating to the online cultural criticism journal, Manifold, which she co-founded in 2016.