Conduct advanced research into kidney disease pathophysiology, particularly Focal Segmental Glomerulosclerosis (FSGS), focusing on the regulation of the glomerular filtration barrier through various mechanisms. Employ sophisticated laboratory techniques such as cell and tissue culture, gene expression, biochemical markers, ELISA, knockdown experiments, and immunohistochemistry to investigate podocyte signaling pathways and implications in disease progression. Develop and test potential therapeutic interventions using animal models, enhancing understanding of glomerular diseases. Oversee laboratory operations and coordinate research activities, maintaining high standards of scientific inquiry and team productivity. Facilitate grant writing and submissions, securing essential research funding and supporting the institution's scientific endeavors.• Secured research funding to advance understanding of molecular mechanisms underlying FSGS development and progression. • Established in vivo animal research protocols, strengthening the institution's research capabilities.• Developed new laboratory techniques and protocols, optimizing research efficiency and output.• Explored the impact of circulating factors, including suPAR and TNF, on the permeability of the glomerular filtration barrier.• Collaborated with physicians and pharmaceutical companies to investigate potential therapies for FSGS patients.• Investigated the role of podocyte injury, inflammation, and fibrosis in FSGS progression using histopathological approaches.• Published multiple articles in peer-reviewed journals, disseminating significant findings to the scientific community.• Trained laboratory members, fostering a skilled and knowledgeable research team.

Designed and executed experiments to elucidate the function of BKCa and TRPC6 channels in podocytes, enhancing understanding of kidney disease mechanisms. Pioneered novel protein interaction studies using yeast two-hybrid screening, contributing to the field's knowledge base. • Investigated podocyte ion channel regulation, including insulin and glucose effects, NMDA receptor expression, and protein interactions, advancing kidney disease understanding.• Significantly contributed to the research team's efforts, resulting in the publication of multiple peer-reviewed articles.• Played a key role in drafting grant proposals and scientific manuscripts, demonstrating research acumen and commitment to advancing the scientific community's knowledge.• Enhanced laboratory protocols by introducing innovative molecular techniques such as, mutagenesis technique, protein-protein interaction, cellular imaging techniques, and electrophysiology, leading to more efficient and accurate experimentation.• Fostered collaborative relationships with other researchers and institutions, enriching the research and discovery process.

Conducted advanced molecular genetics research on lysosomal storage diseases, with a focus on therapeutic interventions in Gaucher disease mouse models. Developed gene and cell therapy techniques utilizing lentiviral vectors to advance scientific understanding. Mastered a broad range of laboratory techniques, including cell and tissue culture, isolation of mesenchymal stem cells (MSCs) from mice bone marrow, molecular and cellular biology, in vivo studies, and immunohistochemistry. Demonstrated proficiency in cell culture, with experience isolating and culturing a variety of cell lines, and excelled in animal handling for breeding, genotyping, and tissue harvesting. • Published findings in top-tier scientific journals, contributing to the body of knowledge in genetic disease research.• Led the development of innovative lentiviral vector approaches, enhancing gene and cell therapy techniques.• Optimized and standardized complex laboratory protocols, ensuring reproducibility and accuracy in research outcomes.• Spearheaded the introduction of novel in vivo study methods for disease modeling and therapeutic assessment.• Expertise in animal injection methods, including intravenous (IV) injection and intraportal injection, for gene and stem cell delivery and experimental manipulation.• Specialized in a suite of molecular biology protocols, including DNA/RNA extraction, PCR/RT-PCR, cloning, and protein assays, to support groundbreaking research findings.• Researched neuroprotective strategies and inflammatory processes in Gaucher disease, enhancing comprehension of disease pathology mechanism.